Most cited papers in Calpain Protease Function and Regulation
What are the most cited papers in Calpain Protease Function and Regulation?
The most cited paper in Calpain Protease Function and Regulation is "Artemisinin Resistance in Plasmodium falciparum Malaria" (Arjen M. Dondorp et al., 2009), with 3,505 citations. Next come "Apoptosis, oncosis, and necrosis. An overview of cell death." (3,335) and "Ischemic Cell Death in Brain Neurons" (3,056).
Showing 50 of 100 papers. Every paper with more than 464 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Artemisinin Resistance in Plasmodium falciparum Malaria Arjen M. Dondorp et al. · New England Journal of Medicine | 29 Jul 2009 | 3,505 |
| 2 | Apoptosis, oncosis, and necrosis. An overview of cell death. Guido Majno, I Joris · PubMed | 1995 | 3,335 |
| 3 | Ischemic Cell Death in Brain Neurons Peter Lipton · Physiological Reviews | 10 Jan 1999 | 3,056 |
| 4 | Regulation of cell death: the calcium–apoptosis link Sten Orrenius, Boris Zhivotovsky, Pierluigi Nicotera · Nature Reviews Molecular Cell Biology | Jul 2003 | 3,018 |
| 5 | The Calpain System Darrel E. Goll, Valery F. Thompson, Hongqi Li et al. · Physiological Reviews | Jul 2003 | 2,837 |
| 6 | Involvement of MACH, a Novel MORT1/FADD-Interacting Protease, in Fas/APO-1- and TNF Receptor–Induced Cell Death Mark Boldin, Tanya M Goncharov, Yury V Goltseve et al. · Cell | Jun 1996 | 2,314 |
| 7 | Spread of Artemisinin Resistance in Plasmodium falciparum Malaria Elizabeth A. Ashley et al. · New England Journal of Medicine | 30 Jul 2014 | 2,295 |
| 8 | Transcriptional regulation by calcium, calcineurin, and NFAT Patrick G. Hogan, Lin Chen, Julie Nardone et al. · Genes & Development | 15 Sep 2003 | 2,019 |
| 9 | Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates Christa Heussen, Eugene B. Dowdle · Analytical Biochemistry | Feb 1980 | 1,987 |
| 10 | cDNA sequence of human apolipoprotein(a) is homologous to plasminogen John W. McLean, James E. Tomlinson, Wun-Jing Kuang et al. · Nature | Nov 1987 | 1,898 |
| 11 | Four deaths and a funeral: from caspases to alternative mechanisms Marcel Leist, Marja Jäättelä · Nature Reviews Molecular Cell Biology | Aug 2001 | 1,599 |
| 12 | Ca2+ Influx Regulates BDNF Transcription by a CREB Family Transcription Factor-Dependent Mechanism Tao Xu, Steven M. Finkbeiner, Donald B. Arnold et al. · Neuron | Apr 1998 | 1,575 |
| 13 | Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus Yukio Horikawa et al. · Nature Genetics | Oct 2000 | 1,478 |
| 14 | The expanding superfamily of phospholipase A2 enzymes: classification and characterization David A. Six, Edward A. Dennis · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | Oct 2000 | 1,357 |
| 15 | Protease activation during apoptosis: Death by a thousand cuts? Séamus J. Martin, Douglas R. Green · Cell | Aug 1995 | 1,331 |
| 16 | Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I Mathew L. Coleman, Erik A. Sahai, Margaret Yeo et al. · Nature Cell Biology | 6 Mar 2001 | 1,309 |
| 17 | Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis Shída Yousefi, Remo Perozzo, Inès Schmid et al. · Nature Cell Biology | 24 Sep 2006 | 1,301 |
| 18 | Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats. Joshua B. Bederson, Lawrence H. Pitts, Isabelle M. Germano et al. · Stroke | Nov 1986 | 1,294 |
| 19 | Caspase Family Proteases and Apoptosis Ting‐Jun Fan, Lihui Han, Ri-Shan Cong et al. · Acta Biochimica et Biophysica Sinica | Nov 2005 | 1,256 |
| 20 | Chaperone Suppression of α-Synuclein Toxicity in a Drosophila Model for Parkinson's Disease Pavan Kumar Auluck, Ho Yin Edwin Chan, John Q. Trojanowski et al. · Science | Feb 2002 | 1,243 |
| 21 | Serpin Structure, Mechanism, and Function Peter G.W. Gettins · Chemical Reviews | 8 Nov 2002 | 1,236 |
| 22 | Nitrogen-Containing Bisphosphonates Inhibit the Mevalonate Pathway and Prevent Post-Translational Prenylation of GTP-Binding Proteins, Including Ras Steven Paul Luckman, David Emlyn Hughes, Fraser P. Coxon et al. · Journal of Bone and Mineral Research | Apr 1998 | 1,193 |
| 23 | Cross-Talk between Two Cysteine Protease Families Toshiyuki Nakagawa, Junying Yuan · The Journal of Cell Biology | 21 Aug 2000 | 1,162 |
| 24 | Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids. Yoshimi Takai, Akira Kishimoto, Yasushi Iwasa et al. · Journal of Biological Chemistry | May 1979 | 1,145 |
| 25 | Cleavage of proBDNF by tPA/Plasmin Is Essential for Long-Term Hippocampal Plasticity Petti T. Pang, Henry K. Teng, Eugene N. Zaitsev et al. · Science | 14 Oct 2004 | 1,141 |
| 26 | Structure of a serpin–protease complex shows inhibition by deformation James A. Huntington, Randy J. Read, Robin W. Carrell · Nature | Oct 2000 | 1,110 |
| 27 | Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial Arjen Dondorp · The Lancet | Aug 2005 | 1,077 |
| 28 | Neurotoxicity induces cleavage of p35 to p25 by calpain Mingsum S Lee, Young T. Kwon, Mingwei Li et al. · Nature | May 2000 | 1,075 |
| 29 | Calcium-activated, phospholipid-dependent protein kinase from rat brain. Subcellular distribution, purification, and properties. Ushio Kikkawa, Yoshimi Takai, Ryoji Minakuchi et al. · Journal of Biological Chemistry | Nov 1982 | 1,009 |
| 30 | Mutations in the proteolytic enzyme calpain 3 cause limb-girdle muscular dystrophy type 2A Isabelle Richard, Odile Broux, Valéerie Allamand et al. · Cell | Apr 1995 | 1,004 |
| 31 | Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate. Hiroyuki Nakanishi, Kim Brewer, John H. Exton · Journal of Biological Chemistry | 1993 | 971 |
| 32 | Human and mouse proteases: a comparative genomic approach Xosé S. Puente, Luis Sánchez‐Pulido, Christopher M. Overall et al. · Nature Reviews Genetics | Jul 2003 | 947 |
| 33 | Enhanced expression of PAI–1 in visceral fat: Possible contributor to vascular disease in obeisty Iichiro Shimomura, Tohru Funahasm, Masahiko Takahashi et al. · Nature Medicine | Jul 1996 | 897 |
| 34 | Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease Chunlong Ma, Michael Dominic Sacco, Brett L. Hurst et al. · Cell Research | 15 Jun 2020 | 893 |
| 35 | Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calcium-dependent protease from rat brain. Masatoshi Inoue, Akira Kishimoto, Yoshimi Takai et al. · Journal of Biological Chemistry | Nov 1977 | 865 |
| 36 | Calcium-activated neutral protease (calpain) system: structure, function, and regulation. Dorothy E. Croall, George Demartino · Physiological Reviews | Jul 1991 | 834 |
| 37 | Cell death modalities: classification and pathophysiological implications Lorenzo Galluzzi, Maria Chiara Maiuri, Ilio Vitale et al. · Cell Death and Differentiation | 13 Apr 2007 | 833 |
| 38 | Daxx, a Novel Fas-Binding Protein That Activates JNK and Apoptosis Xiaolu Yang, Roya Khosravi‐Far, Howard Y. Chang et al. · Cell | Jun 1997 | 832 |
| 39 | Calcium in Ischemic Cell Death Tibor Kristián, Bo K. Siesjö · Stroke | Mar 1998 | 832 |
| 40 | FUNCTIONS OF COATED VESICLES DURING PROTEIN ABSORPTION IN THE RAT VAS DEFERENS Daniel S. Friend, Marilyn G. Farquhar · The Journal of Cell Biology | Nov 1967 | 821 |
| 41 | Brain ischemia and reperfusion: molecular mechanisms of neuronal injury Blaine C. White, Jonathon M. Sullivan, Donald J. DeGracia et al. · Journal of the Neurological Sciences | Oct 2000 | 799 |
| 42 | Novel targets for Huntington's disease in an mTOR-independent autophagy pathway Andrea J. Williams, Sovan Sarkar, Paul A. Cuddon et al. · Nature Chemical Biology | 23 Mar 2008 | 797 |
| 43 | EMERGING ROLES FOR CYSTEINE PROTEASES IN HUMAN BIOLOGY Harold A. Chapman, Richard J. Riese, Guo‐Ping Shi · Annual Review of Physiology | Oct 1997 | 791 |
| 44 | Biochemistry of postmortem muscle — Lessons on mechanisms of meat tenderization Elisabeth Huff Lonergan, Wangang Zhang, Steven Michael Lonergan · Meat Science | 21 May 2010 | 784 |
| 45 | Cell Death in the Pathogenesis of Heart Disease: Mechanisms and Significance Russell S. Whelan, Vladimir Kaplinskiy, Richard N. Kitsis · Annual Review of Physiology | 11 Feb 2010 | 769 |
| 46 | THE PROTEIN KINASE C FAMILY: HETEROGENEITY AND ITS IMPLICATIONS Ushio Kikkawa, Akira Kishimoto, Yasutomi Nishizuka · Annual Review of Biochemistry | Jun 1989 | 741 |
| 47 | Unsaturated diacylglycerol as a possible messenger for the activation of calcium-activated, phospholipid-dependent protein kinase system Yoshimi Takai, Akira Kishimoto, Ushio Kikkawa et al. · Biochemical and Biophysical Research Communications | Dec 1979 | 735 |
| 48 | An overview of the serpin superfamily. Ruby H. P. Law, Qingwei Zhang, Sheena McGowan et al. · Genome biology | 2006 | 724 |
| 49 | Molecular targets in cerebral ischemia for developing novel therapeutics Suresh L. Mehta, Namratta Manhas, Ram Raghubir · Brain Research Reviews | 16 Jan 2007 | 717 |
| 50 | Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2 Bjoern Schwer, Jakob Bunkenborg, Regis O. Verdin et al. · Proceedings of the National Academy of Sciences | 20 Jun 2006 | 713 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.