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Topic · Cell Biology

Calpain Protease Function and Regulation

Calpain Protease Function and Regulation is a research topic within Cell Biology. Science Explorer counts 7.3k research works in it since 1950. 10.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the role of calpain, a calcium-dependent protease, in regulating various cellular processes such as cell migration, neurodegeneration, apoptosis, and its involvement in diseases including diabetes, cancer, and cardiovascular remodeling. The papers also discuss the structure, activation, and inhibition of calpain as a potential therapeutic target.

  • Calpain
  • Cell Migration
  • Neurodegeneration
  • Proteolytic System
  • Apoptosis
  • Diabetes
  • Cancer
  • Mitochondria
  • Inhibitors
  • Cardiovascular Remodeling
Research works
7.3k
fractional, since 1950
In the world top 10%
732
per year above
Top-10% rate
10.0%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-16%
the tick is no change
Largest producer
China
43% of the 10 largest, 2022-now
Calpain Protease Function and Regulation

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