Most cited papers in Enzyme Production and Characterization
What are the most cited papers in Enzyme Production and Characterization?
The most cited paper in Enzyme Production and Characterization is "Solvent content of protein crystals" (Brian W. Matthews, 1968), with 7,987 citations. Next come "The carbohydrate-active enzymes database (CAZy) in 2013" (6,637) and "The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics" (6,110).
Showing 50 of 100 papers. Every paper with more than 953 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Solvent content of protein crystals Brian W. Matthews · Journal of Molecular Biology | Apr 1968 | 7,987 |
| 2 | The carbohydrate-active enzymes database (CAZy) in 2013 Vincent Lombard, Hemalatha Golaconda Ramulu, Élodie Drula et al. · Nucleic Acids Research | 21 Nov 2013 | 6,637 |
| 3 | The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics Brandi L. Cantarel, P. M. Coutinho, Corinne Rancurel et al. · Nucleic Acids Research | 6 Oct 2008 | 6,110 |
| 4 | A MEDIUM FOR THE CULTIVATION OF LACTOBACILLI J. C. de Man, Morrison Rogosa, M. Elisabeth Sharpe · Journal of Applied Bacteriology | Apr 1960 | 5,358 |
| 5 | Microbial Cellulose Utilization: Fundamentals and Biotechnology Lee Rybeck Lynd, Paul J. Weimer, Willem Heber van Zyl et al. · Microbiology and Molecular Biology Reviews | Sep 2002 | 4,736 |
| 6 | Biomass Recalcitrance: Engineering Plants and Enzymes for Biofuels Production Michael E. Himmel, Shi-You Ding, David K. Johnson et al. · Science | 8 Feb 2007 | 4,628 |
| 7 | Phylogenetic structure of the prokaryotic domain: The primary kingdoms Carl R. Woese, George E. Fox · Proceedings of the National Academy of Sciences | Nov 1977 | 4,135 |
| 8 | Collagen Structure and Stability Matthew D. Shoulders, Ronald T. Raines · Annual Review of Biochemistry | 3 Apr 2009 | 3,926 |
| 9 | Inositol trisphosphate and diacylglycerol as second messengers Michael John Berridge · Biochemical Journal | Jun 1984 | 3,535 |
| 10 | A classification of glycosyl hydrolases based on amino acid sequence similarities Bernard Henrissat · Biochemical Journal | Dec 1991 | 3,202 |
| 11 | Biological interactions between polysaccharides and divalent cations: The egg‐box model Gregor T. Grant, Edwin R. Morris, David Allan Rees et al. · FEBS Letters | 15 May 1973 | 2,893 |
| 12 | Glycobiology: Toward Understanding the Function of Sugars Raymond Allen Dwek · Chemical Reviews | 1996 | 2,806 |
| 13 | Engineering the third wave of biocatalysis Uwe T. Bornscheuer, Gjalt W. Huisman, Romas J. Kazlauskas et al. · Nature | May 2012 | 2,648 |
| 14 | The carbohydrate-active enzyme database: functions and literature Élodie Drula, Marie-Line Garron, Suzan Doğan et al. · Nucleic Acids Research | 15 Oct 2021 | 2,603 |
| 15 | Plasminogen Activators, Tissue Degradation, and Cancer Keld Danø, P.A. Andreasen, Jan Grøndahl-Hansen et al. · Advances in cancer research | 1985 | 2,563 |
| 16 | dbCAN2: a meta server for automated carbohydrate-active enzyme annotation Han Zhang, Tanner Yohe, Le Huang et al. · Nucleic Acids Research | 4 May 2018 | 2,550 |
| 17 | Interlaboratory testing of methods for assay of xylanase activity Michael Bailey, Peter Biely, Kaisa S Poutanen · Journal of Biotechnology | May 1992 | 2,469 |
| 18 | Molecular and Biotechnological Aspects of Microbial Proteases Mala B. Rao, Aparna M. Tanksale, Mohini S. Ghatge et al. · Microbiology and Molecular Biology Reviews | Sep 1998 | 2,283 |
| 19 | Chemical Coupling of Peptides and Proteins to Polysaccharides by Means of Cyanogen Halides Rolf Axén, Jerker O. Porath, Sverker Ernback · Nature | Jun 1967 | 2,162 |
| 20 | Pretreatment of lignocellulose: Formation of inhibitory by-products and strategies for minimizing their effects Leif J. Jönsson, Carlos Martı́n · Bioresource Technology | 21 Oct 2015 | 2,150 |
| 21 | Plasminogen: Purification from Human Plasma by Affinity Chromatography Dale G. Deutsch, Edwin T. Mertz · Science | 4 Dec 1970 | 2,146 |
| 22 | The α / β hydrolase fold David L. Ollis, Eong Cheah, Mirosław Cygler et al. · Protein Engineering Design and Selection | 1992 | 2,124 |
| 23 | Method for assay of intestinal disaccharidases Arne Dahlqvist · Analytical Biochemistry | 1964 | 2,059 |
| 24 | Structures and mechanisms of glycosyl hydrolases G.J. Davies, Bernard Henrissat · Structure | Sep 1995 | 2,030 |
| 25 | New families in the classification of glycosyl hydrolases based on amino acid sequence similarities Bernard Henrissat, Amos Bairoch · Biochemical Journal | Aug 1993 | 1,989 |
| 26 | dbCAN: a web resource for automated carbohydrate-active enzyme annotation Yanbin Yin, Xizeng Mao, Jincai Yang et al. · Nucleic Acids Research | 29 May 2012 | 1,982 |
| 27 | Serine Protease Mechanism and Specificity Lizbeth Hedstrom · Chemical Reviews | 23 Nov 2002 | 1,841 |
| 28 | Glutaraldehyde: Behavior in Aqueous Solution, Reaction with Proteins, and Application to Enzyme Crosslinking Isabelle Migneault, Catherine Dartiguenave, Michel J. Bertrand et al. · BioTechniques | Nov 2004 | 1,821 |
| 29 | Xylanases, xylanase families and extremophilic xylanases Tony Collins, Charles Gerday, Georges Feller · FEMS Microbiology Reviews | 22 Jul 2004 | 1,751 |
| 30 | THE TAXONOMIC SIGNIFICANCE OF FERMENTATIVE VERSUS OXIDATIVE METABOLISM OF CARBOHYDRATES BY VARIOUS GRAM NEGATIVE BACTERIA Rudolph Hugh, Einar Leifson · Journal of Bacteriology | Jul 1953 | 1,670 |
| 31 | Structural and sequence-based classification of glycoside hydrolases Bernard Henrissat, G.J. Davies · Current Opinion in Structural Biology | Oct 1997 | 1,662 |
| 32 | Microbiological precipitation of CaCO3 Shannon Stocks-Fischer, Johnna K. Galinat, Sookie S. Bang · Soil Biology and Biochemistry | Oct 1999 | 1,622 |
| 33 | Bacterial alkaline proteases: molecular approaches and industrial applications Rani Gupta, Beg Q., Philipp Lorenz · Applied Microbiology and Biotechnology | Jun 2002 | 1,611 |
| 34 | MEROPS: the database of proteolytic enzymes, their substrates and inhibitors Neil David Rawlings, A. John Barrett, Alex Bateman · Nucleic Acids Research | 15 Nov 2011 | 1,572 |
| 35 | Chemistry and uses of pectin — A review B. R. Thakur, Rakesh Kumar Singh, Avtar K. Handa et al. · Critical Reviews in Food Science and Nutrition | Feb 1997 | 1,564 |
| 36 | Dali: a network tool for protein structure comparison Liisa U. Holm, Chris Sander · Trends in Biochemical Sciences | Nov 1995 | 1,492 |
| 37 | The molecular structures of starch components and their contribution to the architecture of starch granules: A comprehensive review Serge Pérez, Eric Bertoft · Starch - Stärke | 6 Jul 2010 | 1,474 |
| 38 | Industrial enzyme applications Ole Kirk, Torben Vedel Borchert, Claus Crone Fuglsang · Current Opinion in Biotechnology | Aug 2002 | 1,465 |
| 39 | Enzyme immobilization: an overview on techniques and support materials Sumitra Datta, Lowrence Rene Christena, Yamuna Rani Sriramulu Rajaram · 3 Biotech | 5 Jun 2012 | 1,421 |
| 40 | Carrageenans: Biological properties, chemical modifications and structural analysis – A review Vanessa Leiria Campo, Daniel Fábio Kawano, Dílson Braz da Silva et al. · Carbohydrate Polymers | Feb 2009 | 1,406 |
| 41 | Biology of Moderately Halophilic Aerobic Bacteria António Ventosa, Joaquı́n J. Nieto, Aharon Oren · Microbiology and Molecular Biology Reviews | Jun 1998 | 1,404 |
| 42 | Bioconversion of lignocellulose: inhibitors and detoxification Leif J. Jönsson, Björn Alriksson, Nils‐Olof Nilvebrant · Biotechnology for Biofuels | 28 Jan 2013 | 1,401 |
| 43 | Cellulases and related enzymes in biotechnology M. K. Bhat · Biotechnology Advances | Aug 2000 | 1,388 |
| 44 | Proteases and biological control A. H. Gordon · Nature | 18 Nov 1976 | 1,382 |
| 45 | Microbial xylanases and their industrial applications: a review Qasim Khalil Beg, Mukesh Kapoor, L. Mahajan et al. · Applied Microbiology and Biotechnology | Aug 2001 | 1,377 |
| 46 | Food proteins and their applications Patrick F. Fox · International Dairy Journal | Jun 1997 | 1,374 |
| 47 | An Oxidative Enzyme Boosting the Enzymatic Conversion of Recalcitrant Polysaccharides Gustav Vaaje‐Kolstad, Bjørge Westereng, Svein Jarle Horn et al. · Science | 7 Oct 2010 | 1,367 |
| 48 | Metagenomic Discovery of Biomass-Degrading Genes and Genomes from Cow Rumen Matthias Hess, Alexander Sczyrba, Rob S Egan et al. · Science | 27 Jan 2011 | 1,367 |
| 49 | Properties and applications of starch-converting enzymes of the α-amylase family Marc J. E. C. van der Maarel, Bart van der Veen, Joost C.M. Uitdehaag et al. · Journal of Biotechnology | Mar 2002 | 1,366 |
| 50 | Updating the sequence-based classification of glycosyl hydrolases Bernard Henrissat, Amos Bairoch · Biochemical Journal | Jun 1996 | 1,362 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.