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Most cited papers in Folate and B Vitamins Research

What are the most cited papers in Folate and B Vitamins Research?

The most cited paper in Folate and B Vitamins Research is "Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent" (Jozef Sedlak, Raymond H. Lindsay, 1968), with 8,107 citations. Next come "‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*" (6,495) and "A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase" (5,732).

Showing 50 of 100 papers. Every paper with more than 1,036 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent Jozef Sedlak, Raymond H. Lindsay · Analytical Biochemistry 1968 8,107
2 ‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?* George Davey Smith, Shah B J Ebrahim · International Journal of Epidemiology Feb 2003 6,495
3 A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase Phyllis Frosst, Henk J. Blom, Renate Milos et al. · Nature Genetics Open access May 1995 5,732
4 Mendelian randomization: genetic anchors for causal inference in epidemiological studies George Davey Smith, Gibran Hemani · Human Molecular Genetics Open access 4 Jul 2014 5,184
5 Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology Debbie A. Lawlor, Roger M. Harbord, Jonathan A C Sterne et al. · Statistics in Medicine 20 Sep 2007 5,071
6 Worldwide Epidemiology of Atrial Fibrillation Sumeet S. Chugh, Rasmus J. Havmoeller, Kumar Narayanan et al. · Circulation Open access 17 Dec 2013 4,597
7 Proteobacteria: microbial signature of dysbiosis in gut microbiota Na-Ri Shin, Tae Woong Whon, Jin‐Woo Bae · Trends in biotechnology Review 22 Jul 2015 4,155
8 Glutathione Metabolism and Its Implications for Health Guoyao Wu, Joanne R. Lupton, Nancy D. Turner et al. · Journal of Nutrition Open access Mar 2004 3,876
9 The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association Naga Chalasani, Zobair M. Younossi, Joel E. Lavine et al. · Hepatology 6 Apr 2012 3,843
10 A Quantitative Assessment of Plasma Homocysteine as a Risk Factor for Vascular Disease Carol J. Boushey · JAMA 4 Oct 1995 3,609
11 Robbins and Cotran Pathologic Basis of Disease Syed A. Hoda, Raza S. Hoda · American Journal of Clinical Pathology 13 Aug 2020 3,387
12 Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk W.H. Wilson Tang, Zeneng Wang, Bruce S. Levison et al. · New England Journal of Medicine Open access 24 Apr 2013 3,386
13 Plasma Homocysteine as a Risk Factor for Dementia and Alzheimer's Disease Sudha S. Seshadri, Alexa S. Beiser, Jacob Selhub et al. · New England Journal of Medicine Open access 14 Feb 2002 3,250
14 Prevention of the First Occurrence of Neural-Tube Defects by Periconceptional Vitamin Supplementation Andrew E. Czeizel, István Dudás · New England Journal of Medicine 24 Dec 1992 3,220
15 Independent risk factors for atrial fibrillation in a population-based cohort. The Framingham Heart Study Emelia J. Benjamin · JAMA 16 Mar 1994 2,929
16 RECOGNITION OF THE FETAL ALCOHOL SYNDROME IN EARLY INFANCY KennethL. Jones, DavidW. Smith · The Lancet Nov 1973 2,796
17 Worldwide prevalence of anaemia, WHO Vitamin and Mineral Nutrition Information System, 1993–2005 Erin McLean, Mary E. Cogswell, Ines M. Egli et al. · Public Health Nutrition Open access 23 May 2008 2,766
18 Mendelian Randomization as an Approach to Assess Causality Using Observational Data Peggy Sekula, Fabiola Del Greco M, Cristian Pattaro et al. · Journal of the American Society of Nephrology Open access 2 Aug 2016 2,507
19 One-Carbon Metabolism in Health and Disease Gregory S. Ducker, Joshua D. Rabinowitz · Cell Metabolism Open access 15 Sep 2016 2,353
20 Sensitivity Analyses for Robust Causal Inference from Mendelian Randomization Analyses with Multiple Genetic Variants Stephen Burgess, Jack Bowden, Tove Fall et al. · Epidemiology Open access 4 Oct 2016 2,191
21 Homocysteine and Cardiovascular Disease Helga Refsum, Per Magne Ueland, Ottar Kjell Nygard et al. · Annual Review of Medicine Review Feb 1998 2,182
22 Hyperhomocysteinemia: An Independent Risk Factor for Vascular Disease Robert Clarke, Leslie Daly, Killian Robinson et al. · New England Journal of Medicine Open access 25 Apr 1991 2,180
23 Association Mapping in Structured Populations Jonathan K. Pritchard, Matthew Stephens, Noah A. Rosenberg et al. · The American Journal of Human Genetics Open access Jul 2000 2,122
24 Homocysteine and Risk of Ischemic Heart Disease and Stroke Homocysteine Studies Collaboration · JAMA Open access 23 Oct 2002 2,077
25 Hepatic encephalopathy—Definition, nomenclature, diagnosis, and quantification: Final report of the Working Party at the 11th World Congresses of Gastroenterology, Vienna, 1998 Péter Ferenci, Alan H. Lockwood, Kevin D. Mullen et al. · Hepatology Open access Mar 2002 2,048
26 Homocysteine and Atherothrombosis George N. Welch, Joseph Loscalzo · New England Journal of Medicine 9 Apr 1998 2,017
27 The importance of glutathione in human disease Danyelle M. Townsend, Kenneth D. Tew, Haïm Tapiero · Biomedicine & Pharmacotherapy Open access May 2003 2,015
28 Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study Jan Heeringa, Deirdre A.M. van der Kuip, Albert Hofman et al. · European Heart Journal 9 Mar 2006 1,963
29 Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis David S Wald, Malcolm Law, Joan K Morris · BMJ ReviewOpen access 21 Nov 2002 1,954
30 Vitamin Status and Intake as Primary Determinants of Homocysteinemia in an Elderly Population Jacob Selhub · JAMA 8 Dec 1993 1,923
31 Updated national birth prevalence estimates for selected birth defects in the United States, 2004–2006 Samantha E. Parker, Cara T. Mai, Mark A. Canfield et al. · Birth Defects Research Part A Clinical and Molecular Teratology 28 Sep 2010 1,908
32 Oxidative Damage Is the Earliest Event in Alzheimer Disease Akihiko Nunomura, George Perry, Gjumrakch Aliev et al. · Journal of Neuropathology & Experimental Neurology Open access Aug 2001 1,894
33 Plasma Homocysteine Levels and Mortality in Patients with Coronary Artery Disease Ottar Kjell Nygard, Jan Erik Nordrehaug, Helga Refsum et al. · New England Journal of Medicine Open access 24 Jul 1997 1,776
34 Maternal Pesticide Exposure from Multiple Sources and Selected Congenital Anomalies Gary M. Shaw, Cathy R. Wasserman, Cynthia D. O’Malley et al. · Epidemiology 1999 1,771
35 Nutrition Intervention Trials in Linxian, China: Supplementation With Specific Vitamin/Mineral Combinations, Cancer Incidence, and Disease-Specific Mortality in the General Population William J. Blot, Jingyuan Li, Phil R. Taylor et al. · JNCI Journal of the National Cancer Institute 15 Sep 1993 1,767
36 Plasma homocysteine as a risk factor for vascular disease. The European Concerted Action Project. Ian M. Graham et al. · PubMed 11 Jun 1997 1,757
37 Oxidative Nucleobase Modifications Leading to Strand Scission Cynthia J. Burrows, James G. Muller · Chemical Reviews Review Apr 1998 1,745
38 Homocysteine Lowering with Folic Acid and B Vitamins in Vascular Disease The Heart Outcomes Prevention Evaluation (HOPE) 2 Investigators · New England Journal of Medicine Open access 12 Mar 2006 1,736
39 A Prospective Study of Plasma Homocyst(e)ine and Risk of Myocardial Infarction in US Physicians Meir J. Stampfer · JAMA 19 Aug 1992 1,681
40 Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies Wei Zhou, Jonas Bille Nielsen, Lars G. Fritsche et al. · Nature Genetics Open access 8 Aug 2018 1,619
41 Bacteria as vitamin suppliers to their host: a gut microbiota perspective Jean Guy LeBlanc, Christian Milani, Graciela Savoy de Giori et al. · Current Opinion in Biotechnology ReviewOpen access 30 Aug 2012 1,613
42 Management of Sickle Cell Disease Barbara P. Yawn, George R. Buchanan, Araba Afenyi‐Annan et al. · JAMA 9 Sep 2014 1,608
43 A Common Allele on Chromosome 9 Associated with Coronary Heart Disease Ruth McPherson, Alexander Pertsemlidis, Nihan Kavaslar et al. · Science Open access 3 May 2007 1,593
44 A Second Common Mutation in the Methylenetetrahydrofolate Reductase Gene: An Additional Risk Factor for Neural-Tube Defects? Nathalie M. J. van der Put, Fons Gabreëls, E M Stevens et al. · The American Journal of Human Genetics Open access May 1998 1,564
45 Review on iron and its importance for human health. Nazanin Abbaspour, Richard Hurrell, Roya Kelishadi · PubMed Open access Feb 2014 1,492
46 Causal Knowledge as a Prerequisite for Confounding Evaluation: An Application to Birth Defects Epidemiology Miguel Ángel Hernán · American Journal of Epidemiology 15 Jan 2002 1,489
47 Global epidemiology of atrial fibrillation: An increasing epidemic and public health challenge Giuseppe Lippi, Fabián Sanchis‐Gomar, Gianfranco Cervellin · International Journal of Stroke 19 Jan 2020 1,483
48 AHA Dietary Guidelines Ronald M. Krauss, Robert H. Eckel, Barbara V. Howard et al. · Circulation Open access 31 Oct 2000 1,462
49 Homocysteine Lowering and Cardiovascular Events after Acute Myocardial Infarction Kaare Harald Bønaa, Inger Njølstad, Per Magne Ueland et al. · New England Journal of Medicine Open access 12 Mar 2006 1,459
50 Projections on the number of individuals with atrial fibrillation in the European Union, from 2000 to 2060 B. P. Krijthe, Anton Eduard Kunst, Emelia J. Benjamin et al. · European Heart Journal Open access 30 Jul 2013 1,452

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.