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Most cited papers in Heterotopic Ossification and Related Conditions

Heterotopic Ossification and Related Conditions

What are the most cited papers in Heterotopic Ossification and Related Conditions?

The most cited paper in Heterotopic Ossification and Related Conditions is "Ectopic Ossification Following Total Hip Replacement" (Andrew F. Brooker, Jack W. Bowerman, Robert Anthony Robinson et al., 1973), with 2,819 citations. Next come "Ectopic Ossification Following Total Hip Replacement: Incidence and a Method of Classification" (2,548) and "SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7" (1,670).

Showing 50 of 98 papers. Every paper with more than 347 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Ectopic Ossification Following Total Hip Replacement Andrew F. Brooker, Jack W. Bowerman, Robert Anthony Robinson et al. · Journal of Bone and Joint Surgery Dec 1973 2,819
2 Ectopic Ossification Following Total Hip Replacement: Incidence and a Method of Classification Paul A. Banaszkiewicz Book chapter 7 Dec 2013 2,548
3 SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7 Gareth J. Inman, Francisco José Nicolás, James F. Callahan et al. · Molecular Pharmacology Jul 2002 1,670
4 TGF-β and BMP signaling in osteoblast, skeletal development, and bone formation, homeostasis and disease Mengrui Wu, Guiqian Chen, Yiping Li · Bone Research Open access 26 Apr 2016 1,642
5 Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism Takashi Shimada, Makoto Kakitani, Y. Yamazaki et al. · Journal of Clinical Investigation Open access 15 Feb 2004 1,377
6 Gout Nicola Dalbeth, Anna L. Gosling, Angelo Gaffo et al. · The Lancet 30 Mar 2021 1,346
7 A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva Eileen Malko Shore, Meiqi Xu, George J. Feldman et al. · Nature Genetics 23 Apr 2006 1,243
8 A Controlled Trial of High-Dose Intravenous Immune Globulin Infusions as Treatment for Dermatomyositis Marinos C. Dalakas, Isabel Illa, James M. Dambrosia et al. · New England Journal of Medicine Open access 30 Dec 1993 1,140
9 Bone Morphogenetic Protein (BMP) signaling in development and human diseases Richard N. Wang, Jordan J. Green, Zhongliang Wang et al. · Genes & Diseases Open access 27 Jul 2014 1,077
10 Vascular Calcification Linda L. Demer, Yin Tintut · Circulation Open access 2 Jun 2008 1,076
11 Bone morphogenetic protein receptors and signal transduction Kohei Miyazono, Yuji Kamiya, Masato Morikawa · The Journal of Biochemistry 17 Sep 2009 1,008
12 Polymyositis, Dermatomyositis, and Inclusion-Body Myositis Marinos C. Dalakas · New England Journal of Medicine 21 Nov 1991 948
13 Vascular Calcification Rebecca C. Johnson, Jane A. Leopold, Joseph Loscalzo · Circulation Research 9 Nov 2006 941
14 Alkaline phosphatase: Structure, expression and its function in bone mineralization Selvaraj Vimalraj · Gene 6 Jun 2020 917
15 Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways Giorgio Lagna, Akiko Hata, Ali Hemmati‐Brivanlou et al. · Nature Oct 1996 915
16 The serum protein α2–Heremans-Schmid glycoprotein/fetuin-A is a systemically acting inhibitor of ectopic calcification Cora Schäfer, Alexander Heiss, Anke Schwarz et al. · Journal of Clinical Investigation Open access Aug 2003 914
17 Alkaline Phosphatase: An Overview Ujjawal Sharma, Deeksha Pal, Rajendra Prasad · Indian Journal of Clinical Biochemistry Open access 25 Nov 2013 910
18 Ectopic ossification following total hip replacement. Incidence and a method of classification. Andrew F. Brooker, Jack W. Bowerman, Robert Anthony Robinson et al. · PubMed Dec 1973 899
19 BMP signalling in skeletal development, disease and repair Valerie S Salazar, Laura W. Gamer, Vicki Rosen · Nature Reviews Endocrinology Review 19 Feb 2016 898
20 Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization Lovisa Hessle, Kristen A. Johnson, H. Clarke Anderson et al. · Proceedings of the National Academy of Sciences Open access 24 Jun 2002 866
21 Intracortical remodelling and porosity in the distal radius and post-mortem femurs of women: a cross-sectional study Roger Zebaze, Ali Ghasemzadeh, Ann Bohte et al. · The Lancet May 2010 860
22 The role of alkaline phosphatase in mineralization Ellis E. Golub, Kathleen Boesze‐Battaglia · Current Opinion in Orthopedics 14 Aug 2007 835
23 Smooth Muscle Cell Phenotypic Transition Associated With Calcification Susie A. Steitz, Mei Y. Speer, Gabrielle Curinga et al. · Circulation Research 7 Dec 2001 823
24 Bone formation by three-dimensional stromal osteoblast culture in biodegradable polymer scaffolds Susan L. Ishaug, Genevieve M. Crane, Michael J. Miller et al. · Journal of Biomedical Materials Research Jul 1997 817
25 Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4. Peter ten Dijke, Hidetoshi Yamashita, T. Kuber Sampath et al. · Journal of Biological Chemistry Open access Jun 1994 738
26 Bone Morphogenetic Proteins: A critical review Beth C. Bragdon, Oleksandra Moseychuk, Sven Saldanha et al. · Cellular Signalling 17 Oct 2010 723
27 The Mechanism of Mineralization and the Role of Alkaline Phosphatase in Health and Disease Hideo Orimo · Journal of Nippon Medical School Open access 2010 717
28 Effects of Mechanical Factors on the Fracture Healing Process L. Claes, Christa A. Heigele, Cornelia Neidlinger‐Wilke et al. · Clinical Orthopaedics and Related Research Oct 1998 716
29 ANTERIOR FEMORO-ACETABULAR IMPINGEMENT DUE TO ACETABULAR RETROVERSION Klaus Arno Siebenrock, Ralf Schoeniger, Reinhold Ganz · Journal of Bone and Joint Surgery Feb 2003 715
30 Conversion of vascular endothelial cells into multipotent stem-like cells Damian Medici, Eileen Malko Shore, Vitali Y. Lounev et al. · Nature Medicine Open access 21 Nov 2010 675
31 Treatment of primary osteoarthritis of the hip. A comparison of total joint and surface replacement arthroplasty. H C Amstutz, Brandon J. Thomas, Riyaz H. Jinnah et al. · Journal of Bone and Joint Surgery Feb 1984 653
32 Prospective analysis of hip arthroscopy with 2‐year follow‐up J. W. Thomas Byrd, Kay S. Jones · Arthroscopy The Journal of Arthroscopic and Related Surgery Sep 2000 647
33 BMP type I receptor inhibition reduces heterotopic ossification Paul B. Yu, Donna Y. Deng, Carol S. C. Lai et al. · Nature Medicine Open access 24 Nov 2008 642
34 Osteoblast Differentiation at a Glance Arkady Rutkovskiy, Kåre‐Olav Stensløkken, Ingvar Jarle Vaage · Medical science monitor basic research/Medical science monitor. Basic research Open access 26 Sep 2016 638
35 A clinician's guide to X-linked hypophosphatemia Thomas O. Carpenter, Erik Allen Imel, Ingrid A. Holm et al. · Journal of Bone and Mineral Research Open access 2 May 2011 623
36 Mean 20-year Followup of Bernese Periacetabular Osteotomy Simon Damian Steppacher, Moritz Tannast, Reinhold Ganz et al. · Clinical Orthopaedics and Related Research Open access 30 Apr 2008 617
37 Human Type II Receptor for Bone Morphogenic Proteins (BMPs): Extension of the Two-Kinase Receptor Model to the BMPs Fang Liu, Francesc Ventura, Jacqueline F. Doody et al. · Molecular and Cellular Biology Open access Jul 1995 602
38 TGF-β/BMP signaling and other molecular events: regulation of osteoblastogenesis and bone formation Md Shaifur Rahman, Naznin Akhtar, Hossen Mohammad Jamil et al. · Bone Research Open access 14 Apr 2015 592
39 Safety and efficacy of denosumab for adults and skeletally mature adolescents with giant cell tumour of bone: interim analysis of an open-label, parallel-group, phase 2 study Sant P. Chawla, Robert Mikael Henshaw, Leanne L. Seeger et al. · The Lancet Oncology 15 Jul 2013 589
40 INCLUSION BODY MYOSITIS Barend P. Lotz, Andrew G. Engel, H Nishino et al. · Brain 1989 577
41 The Mode of Bone Morphogenetic Protein (BMP) Receptor Oligomerization Determines Different BMP-2 Signaling Pathways Anja Nohe, Sylke Haßel, Marcelo Ehrlich et al. · Journal of Biological Chemistry Open access Feb 2002 564
42 Vascular Calcification Masahide Mizobuchi, Dwight A. Towler, Eduardo Slatopolsky · Journal of the American Society of Nephrology 28 May 2009 554
43 Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient mice Despina Sitara, Mohammed Shawkat Razzaque, Martina Hesse et al. · Matrix Biology Open access Nov 2004 544
44 Bone Morphogenetic Proteins Takenobu Katagiri, Tetsuro Watabe · Cold Spring Harbor Perspectives in Biology Open access Jun 2016 542
45 BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis Marion Scharpfenecker, Maarten van Dinther, Zhen Liu et al. · Journal of Cell Science 20 Feb 2007 542
46 Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma Kathryn R. Taylor et al. · Nature Genetics Open access 6 Apr 2014 537
47 Hypophosphatasia — aetiology, nosology, pathogenesis, diagnosis and treatment Michael P. Whyte · Nature Reviews Endocrinology Review 19 Feb 2016 515
48 Heterotopic Ossification: A Comprehensive Review Carolyn Ann Meyers, Jeffrey L. Lisiecki, Sarah Miller et al. · JBMR Plus Open access 29 Jan 2019 512
49 An FGF23 missense mutation causes familial tumoral calcinosis with hyperphosphatemia Anna Benet‐Pagès, Peter Orlik, Tim Matthias Strom et al. · Human Molecular Genetics 8 Dec 2004 509
50 Transgenic Mice Expressing Fibroblast Growth Factor 23 under the Control of the α1(I) Collagen Promoter Exhibit Growth Retardation, Osteomalacia, and Disturbed Phosphate Homeostasis Tobias E. Larsson, Richard Marsell, Ernestina Schipani et al. · Endocrinology Mar 2004 503

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.