Topic · Pharmacology
Inflammatory mediators and NSAID effects
Inflammatory mediators and NSAID effects is a research topic within Pharmacology. Science Explorer counts 42k research works in it since 1950. 10.1% of them reached the world's top 10% most cited for their field and year.
This cluster of papers focuses on the use of cyclooxygenase-2 (COX-2) inhibitors, such as rofecoxib, celecoxib, and naproxen, in the context of inflammation and cancer. It explores the gastrointestinal and cardiovascular toxicity, chemopreventive effects, and potential risks associated with these drugs. The cluster also delves into the molecular biology of prostaglandins, particularly prostaglandin E2, and their role in modulating immune responses and promoting cancer growth.
- Cyclooxygenase-2 Inhibitors
- Inflammation
- Cancer
- Prostaglandins
- NSAIDs
- Cardiovascular Risk
- Colorectal Cancer
- Chemoprevention
- Prostaglandin E2
- COX-2
- Research works
- 42k fractional, since 1950
- In the world top 10%
- 4.3k per year above
- Top-10% rate
- 10.1% share of its works in the world top 10%
- Growth, 2018-21 → 2022-25
- -14% the tick is no change
- Largest producer
China
32% of the 10 largest, 2022-now
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