Inflammatory mediators and NSAID effects
Inflammatory mediators and NSAID effects is a research topic within Pharmacology. Science Explorer counts 42k research works in it since 1950. 20.7% of them reached the world's top 10% most cited for their field and year.
This cluster of papers focuses on the use of cyclooxygenase-2 (COX-2) inhibitors, such as rofecoxib, celecoxib, and naproxen, in the context of inflammation and cancer. It explores the gastrointestinal and cardiovascular toxicity, chemopreventive effects, and potential risks associated with these drugs. The cluster also delves into the molecular biology of prostaglandins, particularly prostaglandin E2, and their role in modulating immune responses and promoting cancer growth.
- Cyclooxygenase-2 Inhibitors
- Inflammation
- Cancer
- Prostaglandins
- NSAIDs
- Cardiovascular Risk
- Colorectal Cancer
- Chemoprevention
- Prostaglandin E2
- COX-2
- Research works
- 42k fractional, since 1950
- In the world top 10%
- 8.8k per year above
- Top-10% rate
- 20.7% share of its works in the world top 10%
- Growth, 2013–17 → 2018–22
- -11% the tick is no change
This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.
Which countries lead Inflammatory mediators and NSAID effects research?
By volume, China and the United States publish the most (756 and 627 works in 2022–2025).
By volume, 2022–2025
- 1 China 756 works
- 2 United States 627 works
- 3 India 250 works
- 4 Japan 148 works
- 5 South Korea 127 works
- 6 United Kingdom 92 works
- 7 Italy 89 works
- 8 Germany 88 works
- 9 Egypt 86 works
- 10 Russia 85 works
How concentrated that is
The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.
Shares of the rows listed above, not of the whole node.
Which institutions lead Inflammatory mediators and NSAID effects research?
By volume in 2022–2025, Cairo University publishes the most Inflammatory mediators and NSAID effects research, followed by University of North Carolina at Chapel Hill and Chinese Academy of Medical Sciences & Peking Union Medical College.
By volume, 2022–2025
- 1 Cairo UniversityEgypt 15 works
- 2 University of North Carolina at Chapel HillUnited States 12 works
- 3 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 11 works
- 4 Sun Yat-sen UniversityChina 10 works
- 5 Sichuan UniversityChina 10 works
- 6 Harvard UniversityUnited States 9 works
- 7 Huazhong University of Science and TechnologyChina 8 works
- 8 Jagiellonian UniversityPoland 7 works
- 9 Peking UniversityChina 7 works
- 10 University of MichiganUnited States 7 works
Who are the leading researchers in Inflammatory mediators and NSAID effects?
The most-cited researchers publishing on Inflammatory mediators and NSAID effects include Giuseppe Remuzzi, Cyrus Cooper and Hermann Brenner.
- 1 Giuseppe Remuzzi Italy 8.1k citations
- 2 Cyrus Cooper United Kingdom 7.2k citations
- 3 Hermann Brenner Germany 5.8k citations
- 4 George Davey Smith United Kingdom 4.9k citations
- 5 Harlan M. Krumholz United States 4.7k citations
- 6 André G. Uitterlinden Netherlands 4.4k citations
Ranked by citations received across their whole record, among researchers with at least three works on this topic.
Where is Inflammatory mediators and NSAID effects research done?
The largest centres of Inflammatory mediators and NSAID effects research in 2022–2025 are Beijing (China), Shanghai (China), Guangzhou (China) and Seoul (South Korea). Among places with at least 20 works in it, it is an unusually large share of all research in Giza.
Largest cities, 2022–2025
Where it is the local speciality
- GizaEG · 20.9 works4.2×
Location quotient: how much more of its research is in Inflammatory mediators and NSAID effects than the world average.
Where is the best place to study Inflammatory mediators and NSAID effects?
Among universities, judged by research, Cairo University, Chinese Academy of Medical Sciences & Peking Union Medical College and Harvard University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.
One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.
| # | University | Score | Top 10% | Specialisation | Works | Growth |
|---|---|---|---|---|---|---|
| 1 | Cairo UniversityEgypt | 81.4 | 23.4% | 5.6× | 15 | +20.6% |
| 2 | Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina | 49.1 | 25.8% | 3.4× | 11 | -9.6% |
| 3 | Harvard UniversityUnited States | 43.0 | 30.3% | 2.1× | 9 | -19.1% |
| 4 | Sichuan UniversityChina | 39.0 | 25.8% | 1.7× | 10 | +25.7% |
| 5 | University of North Carolina at Chapel HillUnited States | 31.7 | 4.5% | 2.2× | 12 | +54.9% |
| 6 | Sun Yat-sen UniversityChina | 28.9 | 20.0% | 1.9× | 10 | -21.6% |
Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.
Is Inflammatory mediators and NSAID effects research growing?
Output in 2018–2022 was 11% lower than in 2013–2017, peaking in 2012.
The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.
Which topics inside it are moving
Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.