Cholinesterase and Neurodegenerative Diseases
Cholinesterase and Neurodegenerative Diseases is a research topic within Pharmacology. Science Explorer counts 31k research works in it since 1950. 24.2% of them reached the world's top 10% most cited for their field and year.
This cluster of papers focuses on the pharmacology and toxicology of cholinesterase inhibitors, particularly acetylcholinesterase and butyrylcholinesterase, in the context of neurodegenerative diseases such as Alzheimer's. It explores the development of multi-target-directed ligands, novel drug therapies, and the implications for cognitive deficits. The research also delves into the structure, function, and regulation of cholinesterases, as well as their potential roles in neuroprotection and neurorestoration.
- Cholinesterase Inhibitors
- Acetylcholinesterase
- Butyrylcholinesterase
- Alzheimer's Disease
- Neurodegenerative Diseases
- Multi-Target-Directed Ligands
- Pharmacology
- Toxicology
- Drug Development
- Cognitive Deficits
- Research works
- 31k fractional, since 1950
- In the world top 10%
- 7.6k per year above
- Top-10% rate
- 24.2% share of its works in the world top 10%
- Growth, 2013–17 → 2018–22
- +22% the tick is no change
This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.
Which countries lead Cholinesterase and Neurodegenerative Diseases research?
By volume, China and India publish the most (733 and 705 works in 2022–2025).
By volume, 2022–2025
- 1 China 733 works
- 2 India 705 works
- 3 United States 593 works
- 4 Türkiye 247 works
- 5 Italy 143 works
- 6 Brazil 133 works
- 7 Iran 115 works
- 8 South Korea 115 works
- 9 Russia 114 works
- 10 Pakistan 106 works
How concentrated that is
The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.
Shares of the rows listed above, not of the whole node.
Which institutions lead Cholinesterase and Neurodegenerative Diseases research?
By volume in 2022–2025, University of Florence publishes the most Cholinesterase and Neurodegenerative Diseases research, followed by King Saud University and Cairo University.
By volume, 2022–2025
- 1 University of FlorenceItaly 17 works
- 2 King Saud UniversitySaudi Arabia 17 works
- 3 Cairo UniversityEgypt 16 works
- 4 Banaras Hindu UniversityIndia 15 works
- 5 Shenyang Pharmaceutical UniversityChina 14 works
- 6 Atatürk UniversityTürkiye 14 works
- 7 China Pharmaceutical UniversityChina 12 works
- 8 Chinese Academy of SciencesChina 12 works
- 9 Chitkara UniversityIndia 11 works
- 10 Central University of PunjabIndia 11 works
Who are the leading researchers in Cholinesterase and Neurodegenerative Diseases?
The most-cited researchers publishing on Cholinesterase and Neurodegenerative Diseases include John Hardy, Ronald C. Petersen and Kaj Blennow.
- 1 John Hardy United Kingdom 4k citations
- 2 Ronald C. Petersen United States 4k citations
- 3 Kaj Blennow Sweden 3.4k citations
- 4 J. Andrew McCammon United States 3.4k citations
- 5 K. Barry Sharpless United States 3.3k citations
Ranked by citations received across their whole record, among researchers with at least three works on this topic.
Where is Cholinesterase and Neurodegenerative Diseases research done?
The largest centres of Cholinesterase and Neurodegenerative Diseases research in 2022–2025 are Beijing (China), New Delhi (India), Seoul (South Korea) and Tehran (Iran).
Where is the best place to study Cholinesterase and Neurodegenerative Diseases?
Among universities, judged by research, Central University of Punjab, Atatürk University and Shenyang Pharmaceutical University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.
One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.
| # | University | Score | Top 10% | Specialisation | Works | Growth |
|---|---|---|---|---|---|---|
| 1 | Central University of PunjabIndia | 70.4 | 50.8% | 31.2× | 11 | — |
| 2 | Atatürk UniversityTürkiye | 68.5 | 39.7% | 8.4× | 14 | +148.1% |
| 3 | Shenyang Pharmaceutical UniversityChina | 67.0 | 26.8% | 24.3× | 14 | +199.5% |
| 4 | Banaras Hindu UniversityIndia | 66.2 | 42.3% | 7.1× | 15 | +86.5% |
| 5 | China Pharmaceutical UniversityChina | 65.0 | 39.0% | 12.8× | 12 | +72.1% |
| 6 | King Saud UniversitySaudi Arabia | 61.6 | 32.8% | 4.1× | 17 | +71.5% |
| 7 | University of FlorenceItaly | 60.7 | 24.1% | 7.6× | 18 | +86.3% |
| 8 | GLA UniversityIndia | 57.4 | 33.5% | 12.4× | 10 | — |
| 9 | Cairo UniversityEgypt | 57.0 | 33.3% | 4.6× | 16 | +88.5% |
| 10 | JSS Academy of Higher Education and ResearchIndia | 49.4 | 35.0% | 16.0× | 8 | -5.5% |
Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.
Is Cholinesterase and Neurodegenerative Diseases research growing?
Output in 2018–2022 was 22% higher than in 2013–2017, peaking in 2023. The fastest-growing topics are Cholinesterase and Neurodegenerative Diseases.
The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.
Which topics inside it are moving
Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.