Most cited papers in Paraoxonase enzyme and polymorphisms
What are the most cited papers in Paraoxonase enzyme and polymorphisms?
The most cited paper in Paraoxonase enzyme and polymorphisms is "C-Reactive Protein and Other Markers of Inflammation in the Prediction of Cardiovascular Disease in Women" (Paul M. Ridker, Charles H. Hennekens, Julie E. Buring et al., 2000), with 5,889 citations. Next come "Vitamin E Consumption and the Risk of Coronary Heart Disease in Men" (2,365) and "Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)" (2,158).
Showing 50 of 100 papers. Every paper with more than 400 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | C-Reactive Protein and Other Markers of Inflammation in the Prediction of Cardiovascular Disease in Women Paul M. Ridker, Charles H. Hennekens, Julie E. Buring et al. · New England Journal of Medicine | 23 Mar 2000 | 5,889 |
| 2 | Vitamin E Consumption and the Risk of Coronary Heart Disease in Men Eric B. Rimm, Meir J. Stampfer, Alberto Ascherio et al. · New England Journal of Medicine | 20 May 1993 | 2,365 |
| 3 | Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS) Nigel G. Stephens, A Parsons, Matthew A. Brown et al. · The Lancet | Mar 1996 | 2,158 |
| 4 | Vitamin E Consumption and the Risk of Coronary Disease in Women Meir J. Stampfer, Charles H. Hennekens, JoAnn E. Manson et al. · New England Journal of Medicine | 20 May 1993 | 2,119 |
| 5 | Homocysteine and Risk of Ischemic Heart Disease and Stroke Homocysteine Studies Collaboration · JAMA | 23 Oct 2002 | 2,077 |
| 6 | Method for the measurement of antioxidant activity in human fluids D Koraćević, G Koracevic, V Djordjevic et al. · Journal of Clinical Pathology | May 2001 | 1,984 |
| 7 | Vitamin E Supplementation and Cardiovascular Events in High-Risk Patients The Heart Outcomes Prevention Evaluation Study Investigators · New England Journal of Medicine | 20 Jan 2000 | 1,964 |
| 8 | Inhibition of nitrite formation from hydroxylammoniumchloride: A simple assay for superoxide dismutase Erich F. Elstner, Adelheid Heupel · Analytical Biochemistry | Feb 1976 | 1,911 |
| 9 | Homocysteine Lowering and Cardiovascular Events after Acute Myocardial Infarction Kaare Harald Bønaa, Inger Njølstad, Per Magne Ueland et al. · New England Journal of Medicine | 12 Mar 2006 | 1,459 |
| 10 | Antiinflammatory Properties of HDL Philip J. Barter, Stephen James Nicholls, Kerry-Anne Rye et al. · Circulation Research | 14 Oct 2004 | 1,387 |
| 11 | High apolipoprotein B, low apolipoprotein A-I, and improvement in the prediction of fatal myocardial infarction (AMORIS study): a prospective study Göran Walldius, Ingmar Jungner, Ingar Holme et al. · The Lancet | Dec 2001 | 1,246 |
| 12 | Current Perspectives on Arterial Stiffness and Pulse Pressure in Hypertension and Cardiovascular Diseases Michel E. Safar, Bernard I Levy, Harry A.J. Struijker-Boudier · Circulation | 9 Jun 2003 | 1,205 |
| 13 | Does the Interdependence between Oxidative Stress and Inflammation Explain the Antioxidant Paradox? Subrata Kumar Biswas · Oxidative Medicine and Cellular Longevity | 2016 | 1,180 |
| 14 | Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase. M Aviram, Mira Rosenblat, C L Bisgaier et al. · Journal of Clinical Investigation | 15 Apr 1998 | 1,174 |
| 15 | Protective effect of high density lipoprotein associated paraoxonase. Inhibition of the biological activity of minimally oxidized low density lipoprotein. A. D. Watson, J A Berliner, Susan Y. Hama et al. · Journal of Clinical Investigation | Dec 1995 | 1,164 |
| 16 | Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis Diana M. Shih, Lingjie Gu, Yu-Rong Xia et al. · Nature | Jul 1998 | 1,091 |
| 17 | Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomised trials Deepak P. Vivekananthan, Marc S. Penn, Shelly K Sapp et al. · The Lancet | Jun 2003 | 1,086 |
| 18 | Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): randomised placebo-controlled trial Mona Boaz, Shmuel S. Smetana, Talia Weinstein et al. · The Lancet | Oct 2000 | 1,030 |
| 19 | Paraoxonase prevents accumulation of lipoperoxides in low‐density lipoprotein Michael I. Mackness, Sharon Arrol, Paul N. Durrington · FEBS Letters | 29 Jul 1991 | 981 |
| 20 | Dietary Antioxidant Vitamins and Death from Coronary Heart Disease in Postmenopausal Women Lawrence H. Kushi, Aaron R. Folsom, Ronald J. Prineas et al. · New England Journal of Medicine | 2 May 1996 | 965 |
| 21 | Coronary Heart Disease Prediction From Lipoprotein Cholesterol Levels, Triglycerides, Lipoprotein(a), Apolipoproteins A-I and B, and HDL Density Subfractions A. Richey Sharrett, Christie Mitchell Ballantyne, Sean A. Coady et al. · Circulation | 4 Sep 2001 | 943 |
| 22 | MTHFR 677C→T Polymorphism and Risk of Coronary Heart Disease Mariska Klerk, Petra Verhoef, Robert Clarke et al. · JAMA | 23 Oct 2002 | 939 |
| 23 | The Role of Selenium in Inflammation and Immunity: From Molecular Mechanisms to Therapeutic Opportunities Zhi Huang, Aaron H. Rose, Peter R. Hoffmann · Antioxidants and Redox Signaling | 28 Sep 2011 | 918 |
| 24 | Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases Goran Bjelaković, Dimitrinka Nikolova, Lise Lotte Gluud et al. · Cochrane Database of Systematic Reviews | 9 Mar 2012 | 915 |
| 25 | POTENTIATION OF THE T-LYMPHOCYTE RESPONSE TO MITOGENS Igal Gery, Richard K. Gershon, Byron H. Waksman · The Journal of Experimental Medicine | Jul 1972 | 912 |
| 26 | Vitamins E and C in the Prevention of Cardiovascular Disease in Men Howard D. Sesso · JAMA | 9 Nov 2008 | 910 |
| 27 | Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E–deficient mice Michael Aviram, Leslie Dornfeld, Mira Rosenblat et al. · American Journal of Clinical Nutrition | May 2000 | 867 |
| 28 | Anti-inflammatory HDL becomes pro-inflammatory during the acute phase response. Loss of protective effect of HDL against LDL oxidation in aortic wall cell cocultures. Brian J. Van Lenten, Susan Y. Hama, Frederick C. de Beer et al. · Journal of Clinical Investigation | Dec 1995 | 846 |
| 29 | Paraoxonase and Atherosclerosis Paul N. Durrington, Bharti Mackness, Mike Mackness · Arteriosclerosis Thrombosis and Vascular Biology | Apr 2001 | 820 |
| 30 | Protection of low-density lipoprotein against oxidative modification by high-density lipoprotein associated paraoxonase M MACKNESS, Sharon Arrol, Caroline A. Abbott et al. · Atherosclerosis | Dec 1993 | 816 |
| 31 | Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease Bengt ÖBerg, Elizabeth McMenamin, Frances Lee Lucas et al. · Kidney International | 13 Feb 2004 | 785 |
| 32 | Nitric oxide and oxidative stress in vascular disease Ulrich Förstermann · Pflügers Archiv - European Journal of Physiology | 20 Mar 2010 | 784 |
| 33 | High-Density Lipoprotein Subfractions - What the Clinicians Need to Know Angela Pirillo, Giuseppe Danilo Norata, Alberico Luigi Catapano · Cardiology | 2013 | 747 |
| 34 | The human serum paraoxonase/arylesterase polymorphism. H W Eckerson, C M Wyte, Bert N. La Du · PubMed | Nov 1983 | 732 |
| 35 | Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities Dragomir Ivanov Draganov, John F. Teiber, Audrey Speelman et al. · Journal of Lipid Research | 17 Mar 2005 | 716 |
| 36 | Inverse correlation between plasma vitamin E and mortality from ischemic heart disease in cross-cultural epidemiology KF Gey, Pekka Puska, Pamela Jordan et al. · American Journal of Clinical Nutrition | 1991 | 714 |
| 37 | The Yin and Yang of Oxidation in the Development of the Fatty Streak Mohamad Navab, Judith A. Berliner, Andrew D. Watson et al. · Arteriosclerosis Thrombosis and Vascular Biology | Jul 1996 | 694 |
| 38 | The Human Serum Paraoxonase/Arylesterase Gene (PON1) Is One Member of a Multigene Family Sergio L. Primo-Parmo, Robert C. Sorenson, John F. Teiber et al. · Genomics | May 1996 | 678 |
| 39 | Vascular oxidative stress, nitric oxide and atherosclerosis Huige Li, Sven Horke, Ulrich Förstermann · Atherosclerosis | 9 Sep 2014 | 661 |
| 40 | Selenium and selenoproteins: it’s role in regulation of inflammation Sneha Hariharan, S. Selvakumar · Inflammopharmacology | 6 Mar 2020 | 659 |
| 41 | Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes Michal Harel, Amir Aharoni, Leonid Gaidukov et al. · Nature Structural & Molecular Biology | 18 Apr 2004 | 649 |
| 42 | Clinical usefulness of lipid ratios, visceral adiposity indicators, and the triglycerides and glucose index as risk markers of insulin resistance Tingting Du, Gang Yuan, Muxun Zhang et al. · Cardiovascular Diabetology | 18 Oct 2014 | 642 |
| 43 | Mechanical stress mechanisms and the cell. An endothelial paradigm. Peter Francis Davies, S. C. Tripathi · Circulation Research | Feb 1993 | 633 |
| 44 | Mammalian lignan production from various foods Lilian U. Thompson, Paul A. Robb, MARIA R. SERRAINO et al. · Nutrition and Cancer | 1991 | 632 |
| 45 | Lipid Oxidation Products Have Opposite Effects on Calcifying Vascular Cell and Bone Cell Differentiation Farhad Parhami, Andrew D. Morrow, Jennifer P. Balucan et al. · Arteriosclerosis Thrombosis and Vascular Biology | Apr 1997 | 621 |
| 46 | Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: step 1 Mohamad Navab, Susan Y. Hama, C. Justin Cooke et al. · Journal of Lipid Research | Sep 2000 | 611 |
| 47 | HDL and arteriosclerosis: beyond reverse cholesterol transport Jerzy–Roch Nofer, Beate E. Kehrel, Manfred Fobker et al. · Atherosclerosis | Mar 2002 | 603 |
| 48 | The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin Holly G. Davies, Rebecca J. Richter, Matthew Keifer et al. · Nature Genetics | Nov 1996 | 602 |
| 49 | Human serum paraoxonase (PON 1) is inactivated by oxidized low density lipoprotein and preserved by antioxidants Michael Aviram, Mira Rosenblat, Scott S. Billecke et al. · Free Radical Biology and Medicine | Apr 1999 | 601 |
| 50 | Purification of human serum paraoxonase/arylesterase. Evidence for one esterase catalyzing both activities. K Gan, Andrew Smolen, Harry W. Eckerson et al. · Drug Metabolism and Disposition | 1991 | 598 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.