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Phosphodiesterase function and regulation

Phosphodiesterase function and regulation is a research topic within Molecular Biology. Science Explorer counts 10k research works in it since 1952. 10.2% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the molecular regulation and clinical applications of cyclic nucleotide phosphodiesterases (PDEs), particularly in the context of cAMP signaling, schizophrenia genetics, neuronal development, therapeutic targeting, compartmentalized signaling, Alzheimer's disease treatment, cardiac function regulation, and the development of phosphodiesterase inhibitors.

  • Cyclic Nucleotide Phosphodiesterases
  • cAMP Signaling
  • Schizophrenia Genetics
  • Neuronal Development
  • Therapeutic Targets
  • Compartmentalized Signaling
  • Alzheimer's Disease Treatment
  • Cardiac Function Regulation
  • Phosphodiesterase Inhibitors
  • G Protein-Coupled Receptors
Research works
10k
fractional, since 1952
In the world top 10%
1k
per year above
Top-10% rate
10.2%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+17%
the tick is no change
Largest producer
United States
31% of the 10 largest, 2022-now
Phosphodiesterase function and regulation
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