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Most cited papers in Stress Responses and Cortisol

What are the most cited papers in Stress Responses and Cortisol?

The most cited paper in Stress Responses and Cortisol is "Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults" (Vincent J. Felitti, Robert F. Anda, Dale F. Nordenberg et al., 1998), with 18,997 citations. Next come "Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies" (8,499) and "Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene" (8,164).

Showing 50 of 99 papers. Every paper with more than 2,134 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults Vincent J. Felitti, Robert F. Anda, Dale F. Nordenberg et al. · American Journal of Preventive Medicine Open access May 1998 18,997
2 Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies Undine Emmi Lang, Stefan Borgwardt · Cellular Physiology and Biochemistry Open access 2013 8,499
3 Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene Avshalom Caspi, Karen Sugden, Terrie E. Moffitt et al. · Science 17 Jul 2003 8,164
4 From inflammation to sickness and depression: when the immune system subjugates the brain Robert Dantzer, Jason C. O’Connor, Gregory G. Freund et al. · Nature reviews. Neuroscience ReviewOpen access 12 Dec 2007 7,434
5 Protective and Damaging Effects of Stress Mediators Bruce S. McEwen · New England Journal of Medicine 15 Jan 1998 6,716
6 How Do Glucocorticoids Influence Stress Responses? Integrating Permissive, Suppressive, Stimulatory, and Preparative Actions* Robert Morris Sapolsky, L. Michael Romero, Allan U. Munck · Endocrine Reviews Feb 2000 6,620
7 Effects of stress throughout the lifespan on the brain, behaviour and cognition SONIA J. LUPIEN, Bruce S. McEwen, Megan R. Gunnar et al. · Nature reviews. Neuroscience Review 29 Apr 2009 6,297
8 Epigenetic programming by maternal behavior Ian C.G. Weaver, Nadia Cervoni, Frances A. Champagne et al. · Nature Neuroscience 27 Jun 2004 6,205
9 The ‘Trier Social Stress Test’ – A Tool for Investigating Psychobiological Stress Responses in a Laboratory Setting Clemens Kirschbaum, Karl‐Martin Pirke, Dirk Helmut Hellhammer · Neuropsychobiology 22 Feb 2008 6,194
10 Acute Stressors and Cortisol Responses: A Theoretical Integration and Synthesis of Laboratory Research. Sally S. Dickerson, Margaret E. Kemeny · Psychological Bulletin 2004 5,904
11 Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat Sharon Pellow, Philippe Chopin, Sandra E. File et al. · Journal of Neuroscience Methods Aug 1985 5,844
12 The adolescent brain and age-related behavioral manifestations LINDA PATIA SPEAR · Neuroscience & Biobehavioral Reviews Jun 2000 5,518
13 A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia Kenneth Hargreaves, Ronald A. Dubner, Frederick J. Brown et al. · Pain 1988 5,230
14 Stress, Adaptation, and Disease: Allostasis and Allostatic Load Bruce S. McEwen · Annals of the New York Academy of Sciences May 1998 5,076
15 Physiology and Neurobiology of Stress and Adaptation: Central Role of the Brain Bruce S. McEwen · Physiological Reviews Review Jul 2007 4,968
16 Role of Genotype in the Cycle of Violence in Maltreated Children Avshalom Caspi, Joseph L. McClay, Terrie E. Moffitt et al. · Science 2 Aug 2002 4,873
17 A Meta-Analysis of Cytokines in Major Depression Yekta Dowlati, Nathan Herrmann, Walter Swardfager et al. · Biological Psychiatry Review 17 Dec 2009 4,780
18 Stress and the brain: from adaptation to disease E. R. de Kloet, Marian Joëls, Florian Holsboer · Nature reviews. Neuroscience Review 13 May 2005 4,657
19 The enduring effects of abuse and related adverse experiences in childhood Robert F. Anda, Vincent J. Felitti, J. Douglas Bremner et al. · European Archives of Psychiatry and Clinical Neuroscience Open access 26 Nov 2005 4,308
20 Stress and the Individual Bruce S. McEwen · Archives of Internal Medicine 27 Sep 1993 4,058
21 Characterization of a 41-Residue Ovine Hypothalamic Peptide That Stimulates Secretion of Corticotropin and β-Endorphin Wylie Vale, Joachim Spiess, CATHERINE L. RIVIER et al. · Science 18 Sep 1981 3,979
22 The role of inflammation in depression: from evolutionary imperative to modern treatment target Andrew H. Miller, Charles L. Raison · Nature reviews. Immunology ReviewOpen access 29 Dec 2015 3,963
23 Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression Andrew H. Miller, Vladimir Maletic, Charles L. Raison · Biological Psychiatry Open access 16 Jan 2009 3,889
24 Fitness Effects on the Cognitive Function of Older Adults Stanley J. Colcombe, Arthur F. Kramer · Psychological Science Mar 2003 3,799
25 Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats Joseph Altman, Gopal D. Das · The Journal of Comparative Neurology Jun 1965 3,588
26 The Neuroendocrinology of Stress: A Never Ending Story Stafford Louis Lightman · Journal of Neuroendocrinology Jun 2008 3,574
27 The tail suspension test: A new method for screening antidepressants in mice Lucien Stéru, Raymond Chermat, Bernard Thierry et al. · Psychopharmacology Mar 1985 3,563
28 Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse Patrick O. McGowan, Aya Sasaki, Ana C. D’Alessio et al. · Nature Neuroscience Open access 22 Feb 2009 3,539
29 Are the Dorsal and Ventral Hippocampus Functionally Distinct Structures? Michael S. Fanselow, Hong‐Wei Dong · Neuron Open access 2010 3,475
30 Neural regulation of endocrine and autonomic stress responses Yvonne M. Ulrich‐Lai, James P. Herman · Nature reviews. Neuroscience ReviewOpen access 13 May 2009 3,354
31 Psychological Stress and the Human Immune System: A Meta-Analytic Study of 30 Years of Inquiry. Suzanne C. Segerstrom, Gregory E. Miller · Psychological Bulletin Open access 2004 3,353
32 Biobehavioral responses to stress in females: Tend-and-befriend, not fight-or-flight. Shelley E. Taylor, Laura Cousino Klein, Brian P. Lewis et al. · Psychological Review 2000 3,319
33 The concept of allostasis in biology and biomedicine Bruce S. McEwen, John C. Wingfield · Hormones and Behavior 2003 3,310
34 Stress signalling pathways that impair prefrontal cortex structure and function Amy F.T. Arnsten · Nature reviews. Neuroscience ReviewOpen access 20 May 2009 3,306
35 A meta-analysis of heart rate variability and neuroimaging studies: Implications for heart rate variability as a marker of stress and health Julian Francis Thayer, Fredrik Åhs, Mats G. Fredrikson et al. · Neuroscience & Biobehavioral Reviews Review 11 Dec 2011 3,272
36 Contributions of the Amygdala to Emotion Processing: From Animal Models to Human Behavior Elizabeth A. Phelps, Joseph E. LeDoux · Neuron Open access Oct 2005 3,256
37 Stress and disorders of the stress system George Panagiotis Chrousos · Nature Reviews Endocrinology Review 2 Jun 2009 3,226
38 Autonomic nervous system activity in emotion: A review Sylvia D. Kreibig · Biological Psychology 5 Apr 2010 3,218
39 Neurobiology of Depression Eric J. Nestler, Michel Barrot, Ralph Dileone et al. · Neuron Open access Mar 2002 3,204
40 Psychological Stress and Disease Sheldon Cohen, Denise Janicki‐Deverts, Gregory E. Miller · JAMA 9 Oct 2007 3,195
41 Maternal Care, Hippocampal Glucocorticoid Receptors, and Hypothalamic-Pituitary-Adrenal Responses to Stress Dong Liu, Josie C. Diorio, Beth M. Tannenbaum et al. · Science 12 Sep 1997 3,185
42 Comparison of two modes of stress measurement: Daily hassles and uplifts versus major life events Allen D. Kanner, James C. Coyne, Catherine A. Schaefer et al. · Journal of Behavioral Medicine Mar 1981 3,155
43 Fears, phobias, and preparedness: Toward an evolved module of fear and fear learning. Arne Öhman, Susan Mineka · Psychological Review 2001 3,146
44 Emotional processing in anterior cingulate and medial prefrontal cortex Amit Etkin, Tobias Egner, Raffaël Kalisch · Trends in Cognitive Sciences ReviewOpen access 17 Dec 2010 3,108
45 The use of the elevated plus maze as an assay of anxiety-related behavior in rodents Alicia A. Walf, Cheryl Anne Frye · Nature Protocols Open access Feb 2007 3,106
46 Effect of Treatment With Low Doses of Hydrocortisone and Fludrocortisone on Mortality in Patients With Septic Shock Djillali Annane · JAMA 21 Aug 2002 3,104
47 Physiological Functions of Glucocorticoids in Stress and Their Relation to Pharmacological Actions* Allan U. Munck, Paul M. Guyre, Nikki J. Holbrook · Endocrine Reviews 1984 3,104
48 Beyond diathesis stress: Differential susceptibility to environmental influences. Jay Belsky, Michael Pluess · Psychological Bulletin 2009 3,062
49 Cytokines sing the blues: inflammation and the pathogenesis of depression Charles L. Raison, Lucile Capuron, Andrew H. Miller · Trends in Immunology ReviewOpen access 29 Nov 2005 3,023
50 Rapid Systematic Review: The Impact of Social Isolation and Loneliness on the Mental Health of Children and Adolescents in the Context of COVID-19 Maria Elizabeth Loades, Eleanor Chatburn, Nina Higson‐Sweeney et al. · Journal of the American Academy of Child & Adolescent Psychiatry ReviewOpen access 3 Jun 2020 3,011

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.