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Ubiquitin and proteasome pathways

Ubiquitin and proteasome pathways is a research topic within Molecular Biology. Science Explorer counts 44k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the Ubiquitin-Proteasome Proteolytic Pathway, exploring mechanisms of protein degradation, regulation of E3 Ubiquitin Ligases, roles of Deubiquitinating Enzymes, and the impact of SUMOylation. It also delves into the development of proteasome inhibitors for cancer therapy and the involvement of this pathway in NF-?B activation.

  • Ubiquitin
  • Proteasome
  • Deubiquitinating Enzymes
  • E3 Ubiquitin Ligases
  • SUMOylation
  • Protein Degradation
  • Polyubiquitin Chains
  • Proteasome Inhibitors
  • NF-?B Activation
  • Cancer Therapy
Research works
44k
fractional, since 1950
In the world top 10%
4.4k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+13%
the tick is no change
Largest producer
China
44% of the 10 largest, 2022-now
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