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Topic · Pharmaceutical Science

Chemical Reactions and Isotopes

Chemical Reactions and Isotopes is a research topic within Pharmaceutical Science. Science Explorer counts 27k research works in it since 1950. 12.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the use of deuterium and tritium labeling, hydrogen isotope exchange, and catalysis in drug discovery and development. It explores applications in medicinal chemistry, metabolism studies, and the incorporation of deuterium into pharmaceutical compounds. The research also highlights the use of iridium-catalyzed reactions and the impact of deuterium substitution on drug pharmacokinetics.

  • Deuterium
  • Drug Discovery
  • Isotope Chemistry
  • Medicinal Chemistry
  • Catalysis
  • Pharmaceutical Compounds
  • Tritium Labeling
  • Hydrogen Isotope Exchange
  • Metabolism Studies
  • Iridium-Catalyzed Reactions
Research works
27k
fractional, since 1950
In the world top 10%
3.5k
per year above
Top-10% rate
12.9%
share of its works in the world top 10%
Growth, 2013–17 → 2018–22
+8%
the tick is no change

Which countries lead Chemical Reactions and Isotopes research?

By volume, the United States and China publish the most (444 and 428 works in 2022–2025).

By volume, 2022–2025

  1. 1 United States 444 works
  2. 2 China 428 works
  3. 3 Russia 229 works
  4. 4 India 126 works
  5. 5 Germany 122 works
  6. 6 Japan 104 works
  7. 7 France 81 works
  8. 8 United Kingdom 70 works
  9. 9 Ukraine 65 works
  10. 10 Poland 44 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 25.9%China: 25.0%Russia: 13.4%India: 7.4%6 others listed: 28.4%26%largest
United States444 · 25.9%China428 · 25.0%Russia229 · 13.4%India126 · 7.4%6 others listed486 · 28.4%

Shares of the rows listed above, not of the whole node.

Which institutions lead Chemical Reactions and Isotopes research?

By volume in 2022–2025, Chinese Academy of Sciences publishes the most Chemical Reactions and Isotopes research, followed by University of North Carolina at Chapel Hill and Evalueserve (India).

By volume, 2022–2025

  1. 1 Chinese Academy of SciencesChina 12 works
  2. 2 University of North Carolina at Chapel HillUnited States 10 works
  3. 3 Evalueserve (India)India 10 works
  4. 4 Lomonosov Moscow State UniversityRussia 9 works
  5. 5 Kurchatov InstituteRussia 8 works
  6. 6 Nankai UniversityChina 8 works
  7. 7 Centre National de la Recherche ScientifiqueFrance 8 works
  8. 8 Weatherford CollegeUnited States 8 works
  9. 9 University of Chinese Academy of SciencesChina 7 works
  10. 10 Russian Academy of SciencesRussia 7 works

Who are the leading researchers in Chemical Reactions and Isotopes?

The most-cited researchers publishing on Chemical Reactions and Isotopes include Donald G. Truhlar, George M. Whitesides and Michael J. S. Dewar.

  1. 1 Donald G. Truhlar United States 8.4k citations
  2. 2 George M. Whitesides United States 4.8k citations
  3. 3 Michael J. S. Dewar United States 4.3k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

Where is Chemical Reactions and Isotopes research done?

The largest centres of Chemical Reactions and Isotopes research in 2022–2025 are Moscow (Russia), Beijing (China), Shanghai (China) and Kyiv (Ukraine). Among places with at least 20 works in it, it is an unusually large share of all research in Kyiv.

Largest cities, 2022–2025

  1. 1 Moscow Russia 100 works
  2. 2 Beijing China 67 works
  3. 3 Shanghai China 41 works
  4. 4 Kyiv Ukraine 29 works
  5. 5 Tokyo Japan 28 works
  6. 6 Nanjing China 25 works
  7. 7 Paris France 24 works
  8. 8 Tianjin China 24 works
  9. 9 Hangzhou China 23 works
  10. 10 Saint Petersburg Russia 21 works

Where it is the local speciality

  1. KyivUA · 28.7 works4.4×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Chemical Reactions and Isotopes than the world average.

See Chemical Reactions and Isotopes on the map

Where is the best place to study Chemical Reactions and Isotopes?

Among universities, judged by research, Nankai University, University of North Carolina at Chapel Hill and Lomonosov Moscow State University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

#UniversityScoreTop 10%SpecialisationWorksGrowth
1 Nankai UniversityChina 43.627.8%5.5×8 -34.9%
2 University of North Carolina at Chapel HillUnited States 33.64.0%2.6×10 +208.4%
3 Lomonosov Moscow State UniversityRussia 31.93.6%4.7×9 +10.6%

Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.

Is Chemical Reactions and Isotopes research growing?

Output in 2018–2022 was 8% higher than in 2013–2017, peaking in 2025. The fastest-growing topics are Chemical Reactions and Isotopes.

19801990200020102020
grewheldshrank

The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.