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Topic · Pharmaceutical Science

Drug Solubulity and Delivery Systems

Drug Solubulity and Delivery Systems is a research topic within Pharmaceutical Science. Science Explorer counts 26k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the advances in drug delivery systems, including the use of cyclodextrins, solid dispersions, nanosuspensions, and lipid-based formulations to improve drug solubility and enhance oral delivery. It also explores the application of the Biopharmaceutics Classification System and the development of amorphous pharmaceuticals for improved drug absorption. The research covers a wide range of topics related to pharmaceutical materials and gastrointestinal drug absorption.

  • Cyclodextrins
  • Solid Dispersions
  • Nanosuspensions
  • Lipid-Based Formulations
  • Drug Solubility
  • Oral Delivery
  • Biopharmaceutics Classification System
  • Amorphous Pharmaceuticals
  • Polymeric Materials
  • Gastrointestinal Drug Absorption
Research works
26k
fractional, since 1950
In the world top 10%
2.5k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+2%
the tick is no change
Largest producer
India
46% of the 10 largest, 2022-now
Drug Solubulity and Delivery Systems

Which countries lead Drug Solubulity and Delivery Systems research?

By volume, India and the United States publish the most (1.6k and 477 works in 2022-now).

By volume, 2022-now

  1. 1 India 1.6k works
  2. 2 United States 477 works
  3. 3 China 472 works
  4. 4 Indonesia 168 works
  5. 5 Japan 146 works
  6. 6 United Kingdom 131 works
  7. 7 Germany 122 works
  8. 8 Pakistan 115 works
  9. 9 Saudi Arabia 107 works
  10. 10 Egypt 105 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

India: 45.8%United States: 14.0%China: 13.9%Indonesia: 4.9%6 others listed: 21.3%46%largest
India1,558 · 45.8%United States477 · 14.0%China472 · 13.9%Indonesia168 · 4.9%6 others listed725 · 21.3%

Shares of the rows listed above, not of the whole node.

Which institutions lead Drug Solubulity and Delivery Systems research?

By volume in 2022-now, Hindu College of Pharmacy publishes the most Drug Solubulity and Delivery Systems research, followed by King Saud University and Russian Academy of Sciences.

By volume, 2022-now

  1. 1 Hindu College of PharmacyIndia 75 works
  2. 2 King Saud UniversitySaudi Arabia 28 works
  3. 3 Russian Academy of SciencesRussia 27 works
  4. 4 Purdue University West LafayetteUnited States 25 works
  5. 5 Shenyang Pharmaceutical UniversityChina 24 works
  6. 6 Shri Vile Parle Kelavani MandalIndia 24 works
  7. 7 University of BaghdadIraq 22 works
  8. 8 Savitribai Phule Pune UniversityIndia 22 works
  9. 9 United States Food and Drug AdministrationUnited States 22 works
  10. 10 GITAM UniversityIndia 21 works

Who are the leading researchers in Drug Solubulity and Delivery Systems?

The most-cited researchers publishing on Drug Solubulity and Delivery Systems include Róbert Langer, Amirhossein Sahebkar and George M. Sheldrick.

  1. 1 Róbert Langer United States 303k citations
  2. 2 Amirhossein Sahebkar Iran 258k citations
  3. 3 George M. Sheldrick Germany 220k citations
  4. 4 Hua Zhang Singapore 196k citations
  5. 5 David Julian McClements United States 185k citations
  6. 6 Qiang Zhang China 184k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Drug Solubulity and Delivery Systems?

The most cited paper in Drug Solubulity and Delivery Systems is "Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1" (Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al., 2001), with 18,154 citations. Next come "Molecular Properties That Influence the Oral Bioavailability of Drug Candidates" (8,390) and "Modeling and comparison of dissolution profiles" (5,484).

Most cited papers
#PaperReleasedCitations
1 Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1 Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews Review Mar 2001 18,154
2 Molecular Properties That Influence the Oral Bioavailability of Drug Candidates Daniel F. Veber, Stephen R. Johnson, Hung‐Yuan Cheng et al. · Journal of Medicinal Chemistry 11 May 2002 8,390
3 Modeling and comparison of dissolution profiles Paulo C. Costa, José Manuel Sousa Lobo · European Journal of Pharmaceutical Sciences May 2001 5,484
4 A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability Gordon L. Amidon, Hans Lennernäs, Vinod P. Shah et al. · Pharmaceutical Research Mar 1995 5,389
5 Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices Tsunehiko Higuchi · Journal of Pharmaceutical Sciences Dec 1963 4,890
All 99 most cited papers, with filters and sorting

Where is Drug Solubulity and Delivery Systems research done?

The largest centres of Drug Solubulity and Delivery Systems research in 2022-now are Mumbai (India), Sonīpat (India), Hyderabad (India) and Pune (India). Among places with at least 20 works in it, it is an unusually large share of all research in Sonīpat.

Largest cities, 2022-now

  1. 1 MumbaiIndia 86 works
  2. 2 SonīpatIndia 76 works
  3. 3 HyderabadIndia 71 works
  4. 4 PuneIndia 65 works
  5. 5 AhmedabadIndia 56 works
  6. 6 ChennaiIndia 54 works
  7. 7 BeijingChina 52 works
  8. 8 MoscowRussia 44 works
  9. 9 BaghdadIraq 44 works
  10. 10 RiyadhSaudi Arabia 42 works

Where it is the local speciality

  1. SonīpatIN · 76.4 works35×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Drug Solubulity and Delivery Systems than the world average.

See Drug Solubulity and Delivery Systems on the map

Where is the best place to study Drug Solubulity and Delivery Systems?

Among universities, judged by research, Universität Innsbruck, King Saud University and University of Southern Denmark score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 21.03%fractional works in this field (log) →share of work in the world top 10% →Universität InnsbruckPurdue University We…University of Southe…King Saud University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Universität InnsbruckAustria 67.540.8%8.5×10 +13.2%
2King Saud UniversitySaudi Arabia 56.612.4%6.4×28 +29.6%
3University of Southern DenmarkDenmark 53.918.4%7.5×13 +127.2%
4Purdue University West LafayetteUnited States 52.521.1%6.0×25 -17.0%
5University of MississippiUnited States 52.420.6%13.4×12 +8.6%
6Poznan University of Medical SciencesPoland 47.624.7%13.0×10 +85.1%
7Chitkara UniversityIndia 46.920.1%7.4×13 +27.7%
8Hindu College of PharmacyIndia 46.40.0%164.7×75 -5.5%
9University of CoimbraPortugal 46.033.5%4.1×9 -1.9%
10China Pharmaceutical UniversityChina 42.918.7%16.5×16 +2.4%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Drug Solubulity and Delivery Systems, country by country

Is Drug Solubulity and Delivery Systems research growing?

Output in 2022-2025 was 2% higher than in 2018-2021, peaking in 2022. The fastest-growing topics are Drug Solubulity and Delivery Systems.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Drug Solubulity and Delivery Systems as a percentage of every work published that year, 0.018% in 2024.

still counting0.010%0.020%0.030%Drug Solubulity and Delivery Systems0.020% in 202519801990200020102020

Fractional works of Drug Solubulity and Delivery Systems over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Drug Solubulity and Delivery Systems10.1% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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