Calcium signaling and nucleotide metabolism
Calcium signaling and nucleotide metabolism is a research topic within Physiology. Science Explorer counts 12k research works in it since 1950. 30.3% of them reached the world's top 10% most cited for their field and year.
This cluster of papers explores the evolution, function, and dysregulation of lysosomal calcium signaling, focusing on the role of two-pore channels, NAADP, TRPML1, and cyclic ADP-ribose in intracellular calcium release and endolysosomal trafficking. It also investigates the implications of these mechanisms in diseases such as mucolipidosis type IV and lysosomal storage disorders.
- Lysosomal Calcium Signaling
- Two-pore Channels
- NAADP
- TRPML1
- Endolysosomal Trafficking
- Cyclic ADP-Ribose
- Mucolipidosis Type IV
- Intracellular Calcium Release
- Nicotinic Acid Adenine Dinucleotide Phosphate
- Lysosomal Storage Diseases
- Research works
- 12k fractional, since 1950
- In the world top 10%
- 3.5k per year above
- Top-10% rate
- 30.3% share of its works in the world top 10%
- Growth, 2013–17 → 2018–22
- +16% the tick is no change
Which countries lead Calcium signaling and nucleotide metabolism research?
By volume, China and the United States publish the most (483 and 403 works in 2022–2025).
By volume, 2022–2025
- 1 China 483 works
- 2 United States 403 works
- 3 Germany 92 works
- 4 Japan 85 works
- 5 Italy 67 works
- 6 United Kingdom 67 works
- 7 India 64 works
- 8 South Korea 44 works
- 9 France 43 works
- 10 Canada 36 works
How concentrated that is
The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.
Shares of the rows listed above, not of the whole node.
Which institutions lead Calcium signaling and nucleotide metabolism research?
By volume in 2022–2025, Chinese Academy of Medical Sciences & Peking Union Medical College publishes the most Calcium signaling and nucleotide metabolism research, followed by The University of Texas Southwestern Medical Center and University of Michigan.
By volume, 2022–2025
- 1 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 9 works
- 2 The University of Texas Southwestern Medical CenterUnited States 8 works
- 3 University of MichiganUnited States 8 works
- 4 Ludwig-Maximilians-Universität MünchenGermany 8 works
- 5 University of PennsylvaniaUnited States 7 works
- 6 Harvard UniversityUnited States 7 works
- 7 Universität HamburgGermany 6 works
- 8 University of OxfordUnited Kingdom 6 works
- 9 University Medical Center Hamburg-EppendorfGermany 6 works
- 10 National Institutes of HealthUnited States 6 works
Who are the leading researchers in Calcium signaling and nucleotide metabolism?
The most-cited researchers publishing on Calcium signaling and nucleotide metabolism include Guido Kroemer.
- 1 Guido Kroemer France 4.2k citations
Ranked by citations received across their whole record, among researchers with at least three works on this topic.
Where is Calcium signaling and nucleotide metabolism research done?
The largest centres of Calcium signaling and nucleotide metabolism research in 2022–2025 are Beijing (China), Shanghai (China), Guangzhou (China) and Hangzhou (China).
Where is the best place to study Calcium signaling and nucleotide metabolism?
Among universities, judged by research, Chinese Academy of Medical Sciences & Peking Union Medical College and University of Michigan score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.
| # | University | Score | Top 10% | Specialisation | Works | Growth |
|---|---|---|---|---|---|---|
| 1 | Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina | 41.8 | 30.2% | 5.3× | 9 | +55.6% |
| 2 | University of MichiganUnited States | 34.6 | 43.0% | 3.5× | 8 | +12.6% |
Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.
Is Calcium signaling and nucleotide metabolism research growing?
Output in 2018–2022 was 16% higher than in 2013–2017, peaking in 2020. The fastest-growing topics are Calcium signaling and nucleotide metabolism.
The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.
Which topics inside it are moving
Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.