Adenosine and Purinergic Signaling
Adenosine and Purinergic Signaling is a research topic within Physiology. Science Explorer counts 28k research works in it since 1950. 22.3% of them reached the world's top 10% most cited for their field and year.
This cluster of papers focuses on the molecular physiology and pharmacology of purinergic signalling, including the role of adenosine receptors, P2X receptors, and nucleotide signalling in immune suppression, inflammation, neuroprotection, and the tumor microenvironment. It explores the potential therapeutic targets related to purinergic signalling.
- Purinergic Signalling
- Adenosine Receptors
- P2X Receptors
- Nucleotide Signalling
- Immune Suppression
- Inflammation
- Neuroprotection
- Extracellular ATP
- Tumor Microenvironment
- Therapeutic Targets
- Research works
- 28k fractional, since 1950
- In the world top 10%
- 6.3k per year above
- Top-10% rate
- 22.3% share of its works in the world top 10%
- Growth, 2013–17 → 2018–22
- +10% the tick is no change
Which countries lead Adenosine and Purinergic Signaling research?
By volume, China and the United States publish the most (1k and 723 works in 2022–2025).
By volume, 2022–2025
- 1 China 1k works
- 2 United States 723 works
- 3 Japan 153 works
- 4 Germany 151 works
- 5 Italy 119 works
- 6 India 119 works
- 7 United Kingdom 107 works
- 8 Brazil 96 works
- 9 South Korea 83 works
- 10 France 74 works
How concentrated that is
The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.
Shares of the rows listed above, not of the whole node.
Which institutions lead Adenosine and Purinergic Signaling research?
By volume in 2022–2025, Sun Yat-sen University publishes the most Adenosine and Purinergic Signaling research, followed by Chinese Academy of Medical Sciences & Peking Union Medical College and Sichuan University.
By volume, 2022–2025
- 1 Sun Yat-sen UniversityChina 15 works
- 2 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 14 works
- 3 Sichuan UniversityChina 13 works
- 4 Nanchang UniversityChina 13 works
- 5 Universidade de São PauloBrazil 13 works
- 6 China Pharmaceutical UniversityChina 12 works
- 7 Shanghai Jiao Tong UniversityChina 12 works
- 8 Soochow UniversityChina 12 works
- 9 Chengdu University of Traditional Chinese MedicineChina 11 works
- 10 Central South UniversityChina 11 works
Who are the leading researchers in Adenosine and Purinergic Signaling?
The most-cited researchers publishing on Adenosine and Purinergic Signaling include Giuseppe Remuzzi and Guido Kroemer.
- 1 Giuseppe Remuzzi Italy 8.1k citations
- 2 Guido Kroemer France 4.2k citations
Ranked by citations received across their whole record, among researchers with at least three works on this topic.
Where is Adenosine and Purinergic Signaling research done?
The largest centres of Adenosine and Purinergic Signaling research in 2022–2025 are Beijing (China), Shanghai (China), Guangzhou (China) and Nanjing (China). Among places with at least 20 works in it, it is an unusually large share of all research in Bethesda and Nanchang.
Largest cities, 2022–2025
Where it is the local speciality
- BethesdaUS · 27.9 works6.8×
- NanchangCN · 27.0 works4.5×
Location quotient: how much more of its research is in Adenosine and Purinergic Signaling than the world average.
Where is the best place to study Adenosine and Purinergic Signaling?
Among universities, judged by research, University of Ferrara, China Pharmaceutical University and Nanchang University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.
One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.
| # | University | Score | Top 10% | Specialisation | Works | Growth |
|---|---|---|---|---|---|---|
| 1 | University of FerraraItaly | 74.7 | 52.3% | 18.6× | 11 | +21.3% |
| 2 | China Pharmaceutical UniversityChina | 74.3 | 42.1% | 16.9× | 12 | +140.2% |
| 3 | Nanchang UniversityChina | 62.2 | 35.1% | 8.1× | 13 | +57.1% |
| 4 | Southern Medical UniversityChina | 56.7 | 40.4% | 8.3× | 10 | +35.3% |
| 5 | Anhui Medical UniversityChina | 54.7 | 34.7% | 10.4× | 10 | -2.2% |
| 6 | Chengdu University of Traditional Chinese MedicineChina | 52.7 | 22.1% | 15.6× | 11 | — |
| 7 | Oregon Health & Science UniversityUnited States | 52.2 | 28.7% | 9.6× | 10 | +24.2% |
| 8 | Nanjing Medical UniversityChina | 52.0 | 28.1% | 6.3× | 11 | +139.4% |
| 9 | Soochow UniversityChina | 51.2 | 32.6% | 4.4× | 12 | +105.2% |
| 10 | Sun Yat-sen UniversityChina | 50.7 | 33.1% | 2.9× | 16 | +8.3% |
Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.
Is Adenosine and Purinergic Signaling research growing?
Output in 2018–2022 was 10% higher than in 2013–2017, peaking in 2025. The fastest-growing topics are Adenosine and Purinergic Signaling.
The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.
Which topics inside it are moving
Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.