Liver physiology and pathology
Liver physiology and pathology is a research topic within Hepatology. Science Explorer counts 28k research works in it since 1950. 20.8% of them reached the world's top 10% most cited for their field and year.
This cluster of papers explores the mechanisms, cellular players, and therapeutic targets related to liver fibrosis. It covers topics such as the role of hepatic stellate cells, liver regeneration, TGF-ß signaling, macrophage involvement, MET signaling, oxidative stress, angiogenesis, hepatocyte growth factor, and inflammation in the pathogenesis and treatment of liver fibrosis.
- Hepatic Stellate Cells
- Liver Regeneration
- TGF-ß Signaling
- Macrophages
- MET Signaling
- Fibrogenesis
- Oxidative Stress
- Angiogenesis
- Hepatocyte Growth Factor
- Inflammation
- Research works
- 28k fractional, since 1950
- In the world top 10%
- 5.8k per year above
- Top-10% rate
- 20.8% share of its works in the world top 10%
- Growth, 2013–17 → 2018–22
- -5% the tick is no change
This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.
Which countries lead Liver physiology and pathology research?
By volume, China and the United States publish the most (1.4k and 517 works in 2022–2025).
By volume, 2022–2025
- 1 China 1.4k works
- 2 United States 517 works
- 3 Japan 219 works
- 4 Germany 153 works
- 5 South Korea 132 works
- 6 India 108 works
- 7 Egypt 91 works
- 8 Italy 90 works
- 9 United Kingdom 82 works
- 10 France 66 works
How concentrated that is
The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.
Shares of the rows listed above, not of the whole node.
Which institutions lead Liver physiology and pathology research?
By volume in 2022–2025, Chinese Academy of Medical Sciences & Peking Union Medical College publishes the most Liver physiology and pathology research, followed by Sun Yat-sen University and Nanjing University of Chinese Medicine.
By volume, 2022–2025
- 1 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 23 works
- 2 Sun Yat-sen UniversityChina 23 works
- 3 Nanjing University of Chinese MedicineChina 19 works
- 4 Chengdu University of Traditional Chinese MedicineChina 18 works
- 5 China Pharmaceutical UniversityChina 17 works
- 6 Shanghai University of Traditional Chinese MedicineChina 17 works
- 7 Sichuan UniversityChina 17 works
- 8 Anhui Medical UniversityChina 16 works
- 9 Shanghai Jiao Tong UniversityChina 15 works
- 10 University of PittsburghUnited States 14 works
Who are the leading researchers in Liver physiology and pathology?
The most-cited researchers publishing on Liver physiology and pathology include Michael Karin, Jordi Bruix and Josep M. Llovet.
- 1 Michael Karin United States 4k citations
- 2 Jordi Bruix Spain 3.7k citations
- 3 Josep M. Llovet United States 3.3k citations
- 4 Peter R. Galle Germany 3.3k citations
- 5 Vincenzo Mazzaferro Italy 3k citations
Ranked by citations received across their whole record, among researchers with at least three works on this topic.
Where is Liver physiology and pathology research done?
The largest centres of Liver physiology and pathology research in 2022–2025 are Beijing (China), Shanghai (China), Guangzhou (China) and Nanjing (China). Among places with at least 20 works in it, it is an unusually large share of all research in Nanning.
Largest cities, 2022–2025
Where it is the local speciality
- NanningCN · 21.9 works5.0×
Location quotient: how much more of its research is in Liver physiology and pathology than the world average.
Where is the best place to study Liver physiology and pathology?
Among universities, judged by research, Chengdu University of Traditional Chinese Medicine, Nanjing University of Chinese Medicine and China Pharmaceutical University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.
One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.
| # | University | Score | Top 10% | Specialisation | Works | Growth |
|---|---|---|---|---|---|---|
| 1 | Chengdu University of Traditional Chinese MedicineChina | 74.8 | 57.3% | 23.6× | 18 | +21.1% |
| 2 | Nanjing University of Chinese MedicineChina | 66.2 | 44.3% | 22.3× | 19 | +6.3% |
| 3 | China Pharmaceutical UniversityChina | 60.9 | 35.8% | 23.0× | 17 | +41.0% |
| 4 | Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina | 59.6 | 33.9% | 6.9× | 23 | +60.6% |
| 5 | Anhui Medical UniversityChina | 56.0 | 35.0% | 16.2× | 16 | -14.6% |
| 6 | Zhejiang Chinese Medical UniversityChina | 54.3 | 44.7% | 13.9× | 12 | -45.0% |
| 7 | Southern Medical UniversityChina | 53.6 | 40.5% | 9.4× | 12 | +1.8% |
| 8 | Shanghai University of Traditional Chinese MedicineChina | 52.2 | 29.2% | 25.2× | 17 | -11.5% |
| 9 | Wenzhou Medical UniversityChina | 48.6 | 35.1% | 9.4× | 11 | +9.2% |
| 10 | Mansoura UniversityEgypt | 48.1 | 25.0% | 6.3× | 10 | +182.0% |
Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.
Is Liver physiology and pathology research growing?
Output in 2018–2022 was 5% lower than in 2013–2017, peaking in 2025. The fastest-growing topics are Liver physiology and pathology.
The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.
Which topics inside it are moving
Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.