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Topic · Hepatology

Liver Disease and Transplantation

Liver Disease and Transplantation is a research topic within Hepatology. Science Explorer counts 62k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the management, prognosis, and complications of liver cirrhosis, including topics such as hepatic encephalopathy, portal hypertension, ascites, hepatorenal syndrome, variceal hemorrhage, MELD score, transjugular intrahepatic portosystemic shunt (TIPS), acute-on-chronic liver failure, and coagulopathy.

  • Liver Cirrhosis
  • Hepatic Encephalopathy
  • Portal Hypertension
  • Ascites
  • Hepatorenal Syndrome
  • Variceal Hemorrhage
  • MELD Score
  • Transjugular Intrahepatic Portosystemic Shunt
  • Acute-on-Chronic Liver Failure
  • Coagulopathy
Research works
62k
fractional, since 1950
In the world top 10%
6.1k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+18%
the tick is no change
Largest producer
United States
32% of the 10 largest, 2022-now
Liver Disease and Transplantation

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Liver Disease and Transplantation research?

By volume, the United States and China publish the most (3k and 2.1k works in 2022-now).

By volume, 2022-now

  1. 1 United States 3k works
  2. 2 China 2.1k works
  3. 3 India 1k works
  4. 4 Japan 635 works
  5. 5 Italy 507 works
  6. 6 United Kingdom 506 works
  7. 7 Germany 466 works
  8. 8 South Korea 402 works
  9. 9 Spain 365 works
  10. 10 France 310 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 32.4%China: 22.6%India: 10.8%Japan: 6.8%6 others listed: 27.3%32%largest
United States3,032 · 32.4%China2,117 · 22.6%India1,009 · 10.8%Japan635 · 6.8%6 others listed2,556 · 27.3%

Shares of the rows listed above, not of the whole node.

Which institutions lead Liver Disease and Transplantation research?

By volume in 2022-now, Mayo Clinic publishes the most Liver Disease and Transplantation research, followed by Capital Medical University and Harvard University.

By volume, 2022-now

  1. 1 Mayo ClinicUnited States 100 works
  2. 2 Capital Medical UniversityChina 97 works
  3. 3 Harvard UniversityUnited States 88 works
  4. 4 Sun Yat-sen UniversityChina 79 works
  5. 5 All India Institute of Medical SciencesIndia 77 works
  6. 6 Sichuan UniversityChina 74 works
  7. 7 Institute of Liver and Biliary SciencesIndia 73 works
  8. 8 Zhejiang UniversityChina 65 works
  9. 9 Stanford UniversityUnited States 58 works
  10. 10 Post Graduate Institute of Medical Education and ResearchIndia 55 works

Who are the leading researchers in Liver Disease and Transplantation?

The most-cited researchers publishing on Liver Disease and Transplantation include Douglas G. Altman, Zhong Lin Wang and Ali H. Mokdad.

  1. 1 Douglas G. Altman United Kingdom 862k citations
  2. 2 Zhong Lin Wang United States 491k citations
  3. 3 Ali H. Mokdad United States 429k citations
  4. 4 Peer Bork Germany 396k citations
  5. 5 Zulfiqar Ahmed Bhutta Pakistan 371k citations
  6. 6 John J.V. McMurray United Kingdom 349k citations
  7. 7 Emelia J. Benjamin United States 341k citations
  8. 8 Jun Wang China 340k citations
  9. 9 Giuseppe Remuzzi Italy 328k citations
  10. 10 Mika Kivimäki United Kingdom 318k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Liver Disease and Transplantation?

The most cited paper in Liver Disease and Transplantation is "Transection of the oesophagus for bleeding oesophageal varices" (R. N. H. Pugh, I M Murray-Lyon, J L Dawson et al., 1973), with 8,027 citations. Next come "The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases" (7,419) and "Changes of Intestinal Functions in Liver Cirrhosis" (6,814).

Most cited papers
#PaperReleasedCitations
1 Transection of the oesophagus for bleeding oesophageal varices R. N. H. Pugh, I M Murray-Lyon, J L Dawson et al. · British journal of surgery Aug 1973 8,027
2 The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases Naga Chalasani, Zobair M. Younossi, Joel E. Lavine et al. · Hepatology Open access 17 Jul 2017 7,419
3 Changes of Intestinal Functions in Liver Cirrhosis Hiroshi Fukui, Reiner Wiest · Inflammatory Intestinal Diseases Open access 2016 6,814
4 Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention Zobair M. Younossi, Quentin Mark Anstee, Milena Marietti et al. · Nature Reviews Gastroenterology & Hepatology ReviewOpen access 20 Sep 2017 5,362
5 A Model to Predict Survival in Patients With End–Stage Liver Disease Patrick S. Kamath, Russell H. Wiesner, Michael Malinchoc et al. · Hepatology Feb 2001 5,005
All 99 most cited papers, with filters and sorting

Where is Liver Disease and Transplantation research done?

The largest centres of Liver Disease and Transplantation research in 2022-now are Beijing (China), Seoul (South Korea), New Delhi (India) and London (United Kingdom). Among places with at least 20 works in it, it is an unusually large share of all research in Shibīn al Kawm.

Largest cities, 2022-now

  1. 1 BeijingChina 288 works
  2. 2 SeoulSouth Korea 230 works
  3. 3 New DelhiIndia 178 works
  4. 4 LondonUnited Kingdom 169 works
  5. 5 ShanghaiChina 157 works
  6. 6 GuangzhouChina 152 works
  7. 7 TokyoJapan 138 works
  8. 8 New YorkUnited States 122 works
  9. 9 ParisFrance 118 works
  10. 10 ChengduChina 109 works

Where it is the local speciality

  1. Shibīn al KawmEG · 39.7 works14×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Liver Disease and Transplantation than the world average.

See Liver Disease and Transplantation on the map

Where is the best place to study Liver Disease and Transplantation?

Among universities, judged by research, University of California San Diego, Medical University of Vienna and Virginia Commonwealth University score highest, combining citation excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 19.61%fractional works in this field (log) →share of work in the world top 10% →University of Califo…Virginia Commonwealt…Medical University o…Harvard University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Citation excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1University of California San DiegoUnited States 74.629.4%2.8×30 +26.1%
2Medical University of ViennaAustria 71.316.9%13.5×49 +23.6%
3Virginia Commonwealth UniversityUnited States 70.421.0%11.2×43 -3.1%
4Harvard UniversityUnited States 66.514.7%2.5×88 +1.3%
5University of PennsylvaniaUnited States 65.716.8%4.2×50 +22.7%
6Karolinska InstitutetSweden 65.626.7%3.2×20 +17.7%
7Stanford UniversityUnited States 65.316.7%3.5×58 +47.8%
8University of MichiganUnited States 62.715.7%2.7×46 +31.9%
9University College LondonUnited Kingdom 61.520.1%2.4×44 -13.5%
10Yonsei UniversitySouth Korea 60.518.1%4.4×46 +14.6%

Universities only. The score blends citation excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Liver Disease and Transplantation, country by country

Is Liver Disease and Transplantation research growing?

Output in 2022-2025 was 18% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Liver Disease and Transplantation.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Liver Disease and Transplantation as a percentage of every work published that year, 0.054% in 2024.

still counting0.050%0.10%Liver Disease and Transplantation0.055% in 202519801990200020102020

Fractional works of Liver Disease and Transplantation over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Liver Disease and Transplantation9.8% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

Discussion

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