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Topic · Hepatology

Hepatitis C virus research

Hepatitis C virus research is a research topic within Hepatology. Science Explorer counts 58k research works in it since 1950. 10.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the epidemiology, treatment, and outcomes of hepatitis C virus infection. It covers topics such as antiviral therapy, genetic variation in viral clearance, global epidemiology, liver-related mortality, immune responses, and the impact of comorbidities like HIV and diabetes.

  • Hepatitis C Virus
  • Treatment
  • Ribavirin
  • Interferon
  • Viral Clearance
  • Genetic Variation
  • Epidemiology
  • Liver Disease
  • Immune Response
  • Antiviral Therapy
Research works
58k
fractional, since 1950
In the world top 10%
5.8k
per year above
Top-10% rate
10.0%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-16%
the tick is no change
Largest producer
United States
31% of the 10 largest, 2022-now
Hepatitis C virus research

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Hepatitis C virus research research?

By volume, the United States and China publish the most (1.5k and 1.3k works in 2022-now).

By volume, 2022-now

  1. 1 United States 1.5k works
  2. 2 China 1.3k works
  3. 3 India 456 works
  4. 4 United Kingdom 299 works
  5. 5 Egypt 279 works
  6. 6 Japan 272 works
  7. 7 Italy 268 works
  8. 8 Pakistan 240 works
  9. 9 France 220 works
  10. 10 Spain 214 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 30.6%China: 24.8%India: 9.0%United Kingdom: 5.9%6 others listed: 29.6%31%largest
United States1,546 · 30.6%China1,253 · 24.8%India456 · 9.0%United Kingdom299 · 5.9%6 others listed1,493 · 29.6%

Shares of the rows listed above, not of the whole node.

Which institutions lead Hepatitis C virus research research?

By volume in 2022-now, Capital Medical University publishes the most Hepatitis C virus research research, followed by University of North Carolina at Chapel Hill and Sun Yat-sen University.

By volume, 2022-now

  1. 1 Capital Medical UniversityChina 47 works
  2. 2 University of North Carolina at Chapel HillUnited States 45 works
  3. 3 Sun Yat-sen UniversityChina 44 works
  4. 4 Johns Hopkins UniversityUnited States 42 works
  5. 5 Harvard UniversityUnited States 41 works
  6. 6 Peking UniversityChina 40 works
  7. 7 Ain Shams UniversityEgypt 39 works
  8. 8 InsermFrance 36 works
  9. 9 Sichuan UniversityChina 31 works
  10. 10 Fudan UniversityChina 30 works

Who are the leading researchers in Hepatitis C virus research?

The most-cited researchers publishing on Hepatitis C virus research include Ahmedin Jemal, Christopher J L Murray and Freddie Bray.

  1. 1 Ahmedin Jemal United States 761k citations
  2. 2 Christopher J L Murray United States 583k citations
  3. 3 Freddie Bray France 550k citations
  4. 4 Theo Vos United States 439k citations
  5. 5 Ali H. Mokdad United States 429k citations
  6. 6 Mark J. Daly United States 403k citations
  7. 7 Shizuo Akira Japan 342k citations
  8. 8 Cyrus Cooper United Kingdom 342k citations
  9. 9 Jun Wang China 340k citations
  10. 10 Giuseppe Remuzzi Italy 328k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Hepatitis C virus research?

The most cited paper in Hepatitis C virus research is "Hepatocellular carcinoma" (Josep Maria Llovet, Robin Kate Kelley, Augusto García Villanueva et al., 2021), with 6,733 citations. Next come "Peginterferon Alfa-2a plus Ribavirin for Chronic Hepatitis C Virus Infection" (6,410) and "Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial" (6,056).

Most cited papers
#PaperReleasedCitations
1 Hepatocellular carcinoma Josep Maria Llovet, Robin Kate Kelley, Augusto García Villanueva et al. · Nature Reviews Disease Primers ReviewOpen access 21 Jan 2021 6,733
2 Peginterferon Alfa-2a plus Ribavirin for Chronic Hepatitis C Virus Infection Michael Fried, Mitchell L. Shiffman, K. Rajender Reddy et al. · New England Journal of Medicine 25 Sep 2002 6,410
3 Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial Michael Peter Manns, John G. McHutchison, Stuart C. Gordon et al. · The Lancet Sep 2001 6,056
4 EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection Pietro Lampertico, Kosh Agarwal, Thomas Berg et al. · Journal of Hepatology 18 Apr 2017 5,528
5 Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection†‡ Richard K. Sterling, Eduardo Lissen, Nathan Clumeck et al. · Hepatology Open access 25 May 2006 4,995
All 100 most cited papers, with filters and sorting

Where is Hepatitis C virus research research done?

The largest centres of Hepatitis C virus research research in 2022-now are Beijing (China), London (United Kingdom), Guangzhou (China) and Paris (France). Among places with at least 20 works in it, it is an unusually large share of all research in Kaohsiung City.

Largest cities, 2022-now

  1. 1 BeijingChina 199 works
  2. 2 LondonUnited Kingdom 117 works
  3. 3 GuangzhouChina 104 works
  4. 4 ParisFrance 99 works
  5. 5 SeoulSouth Korea 94 works
  6. 6 ShanghaiChina 89 works
  7. 7 CairoEgypt 88 works
  8. 8 New YorkUnited States 82 works
  9. 9 TaipeiTaiwan 80 works
  10. 10 MadridSpain 70 works

Where it is the local speciality

  1. Kaohsiung CityTW · 37.7 works8.3×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Hepatitis C virus research than the world average.

See Hepatitis C virus research on the map

Where is the best place to study Hepatitis C virus research?

Among universities, judged by research, Chinese University of Hong Kong, Harvard University and National Taiwan University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%30%mean 18.3%fractional works in this field (log) →share of work in the world top 10% →Chinese University o…National Taiwan Univ…Harvard UniversityJohns Hopkins Univer…
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Chinese University of Hong KongChina 71.121.6%4.0×20 +9.7%
2Harvard UniversityUnited States 64.917.0%1.9×41 -29.2%
3National Taiwan UniversityTaiwan 63.519.5%6.5×29 -9.8%
4Johns Hopkins UniversityUnited States 61.510.8%4.0×42 -14.1%
5Capital Medical UniversityChina 61.412.1%6.3×46 +12.6%
6University of Hong KongChina 61.325.3%2.1×14 -16.3%
7University of BristolUnited Kingdom 61.226.9%2.6×10 +12.8%
8Stanford UniversityUnited States 60.420.2%2.7×28 -25.9%
9UNSW SydneyAustralia 60.112.4%4.8×30 -8.1%
10Medizinische Hochschule HannoverGermany 56.317.2%11.7×21 +5.4%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Hepatitis C virus research, country by country

Is Hepatitis C virus research research growing?

Output in 2022-2025 was 16% lower than in 2018-2021, peaking in 2015.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Hepatitis C virus research as a percentage of every work published that year, 0.033% in 2024.

still counting0.050%0.10%Hepatitis C virus research0.031% in 202519801990200020102020

Fractional works of Hepatitis C virus research over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Hepatitis C virus research10.3% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

Questions people ask

Who is researching a cure for hepatitis C?

By volume in 2022-now, Capital Medical University publishes the most Hepatitis C virus research research, followed by University of North Carolina at Chapel Hill and Sun Yat-sen University. By volume, the United States and China publish the most (1.5k and 1.3k works in 2022-now).

All 1,273 questions in the Question Catalogue

Discussion

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