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Company · Redwood City · United States

Guardant (United States)

In research, Guardant (United States) stands highest in Health Sciences (#6,327 of 9,902 worldwide), Medicine (#6,887 of 8,541 worldwide) and Biochemistry, Genetics and Molecular Biology (#2,485 of 2,964 worldwide), 2022-now. Relative to its size it is most specialised in Cancer Research, Oncology and Pulmonary and Respiratory Medicine (Cancer Research is 59.8× its share of world research).

guardanthealth.comROR OpenAlex
World rank, 2022-now
#19,936
of 22,385 · #21,711 all time
Rank in United States
#2,956
of 3,332
Research works
371
▲ 10% vs 2018-21
Citations
5.3k
14.2 per fractional work
Top-10% rate
15.0%
all institutions 10.0%
vs its own fields
0.90×
1.00× is exactly expected
Open access
28%
world 40%
International
19%
world 18%
Guardant (United States)

What is Guardant (United States) known for in research?

The fields where it stands highest, 2022-now, ranked among every institution above the floor in each field.

FieldWorld rankWhere that sitsTop-10% rateWorksAll time
Health SciencesDomain #6,327 of 9,902 15.1%78 #5460
MedicineField #6,887 of 8,541 15.2%78 #6521
Biochemistry, Genetics and Molecular BiologyField #2,485 of 2,964 14.7%62 #3913
Life SciencesDomain #5,756 of 6,403 14.6%63 #7140

Each strip is that field's whole ranked pool, with the notch where Guardant (United States) sits in it, in the colour of the band that rank falls in. The track under the rate is the rate itself: it carries no average mark, because the average differs by field (from about 6% in Dentistry to 21% in Economics).

Which of those standings moved

The same fields on both windows: where it stood over the whole record, and where it stands in 2022-now. The distance is the story, and it is the one thing the two rank columns above cannot show.

  1. Health Sciences#5,460 #6,327
  2. Medicine#6,521 #6,887
  3. Biochemistry, Genetics and Molecular Biology#3,913 #2,485
  4. Life Sciences#7,140 #5,756
all time2022-now, better2022-now, worse

A dot further right is a better standing. Fields it was not ranked in over the whole record are left out.

Which fields of science does Guardant (United States) work in?

In 2022-now, 53% of research at Guardant (United States) is in Health Sciences, 43% in Life Sciences. Its largest fields are Medicine (53%), Biochemistry, Genetics and Molecular Biology (42%), Computer Science (2%). It does 3.0× the world's share of Life Sciences.

Health Sciences: 98 fractional works · 52.9% of its workMedicine: 97 fractional works · 52.8% of its workOncology: 36 fractional works · 19.4% of its workPulmonary and Respiratory Medicine: 31 fractional works · 16.7% of its workPathology and Forensic Medicine: 9 fractional works · 4.9% of its workRadiology, Nuclear Medicine and Imaging: 7 fractional works · 3.8% of its workSurgery: 4 fractional works · 2.0% of its workEpidemiology: 3 fractional works · 1.5% of its workCardiology and Cardiovascular Medicine: 2 fractional works · 1.0% of its workOtorhinolaryngology: 1 fractional works · 0.8% of its workGenetics: 1 fractional works · 0.5% of its workPhysiology: 1 fractional works · 0.4% of its workDermatology: 0 fractional works · 0.3% of its workNeurology: 0 fractional works · 0.2% of its workGastroenterology: 0 fractional works · 0.2% of its workSmaller subfields together: 2 fractional works · 1.1% of its workHealth Professions: 0 fractional works · 0.1% of its workDentistry: 0 fractional works · 0.0% of its workLife Sciences: 80 fractional works · 43.3% of its workBiochemistry, Genetics and Molecular Biology: 78 fractional works · 42.4% of its workCancer Research: 48 fractional works · 26.0% of its workMolecular Biology: 24 fractional works · 12.9% of its workGenetics: 6 fractional works · 3.1% of its workBiotechnology: 1 fractional works · 0.4% of its workImmunology and Microbiology: 1 fractional works · 0.5% of its workImmunology: 1 fractional works · 0.5% of its workAgricultural and Biological Sciences: 1 fractional works · 0.3% of its workPlant Science: 1 fractional works · 0.3% of its workNeuroscience: 0 fractional works · 0.1% of its workPhysical Sciences: 6 fractional works · 3.0% of its workComputer Science: 3 fractional works · 1.5% of its workArtificial Intelligence: 2 fractional works · 1.0% of its workComputer Networks and Communications: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.3% of its workMathematics: 1 fractional works · 0.7% of its workStatistics and Probability: 1 fractional works · 0.6% of its workSmaller subfields together: 0 fractional works · 0.1% of its workEngineering: 1 fractional works · 0.4% of its workBiomedical Engineering: 1 fractional works · 0.4% of its workSmaller subfields together: 0 fractional works · 0.0% of its workEnvironmental Science: 0 fractional works · 0.3% of its workHealth, Toxicology and Mutagenesis: 0 fractional works · 0.3% of its workPhysics and Astronomy: 0 fractional works · 0.1% of its workSocial Sciences: 1 fractional works · 0.8% of its workDecision Sciences: 1 fractional works · 0.4% of its workEconomics, Econometrics and Finance: 1 fractional works · 0.4% of its workEconomics and Econometrics: 1 fractional works · 0.4% of its workPsychology: 0 fractional works · 0.1% of its workALL ITS WORKGuardant (UnitedStates)184fractional works, 2022-now
Life Sciences43%Physical Sciences3%Health Sciences53%Social Sciences1%

Each ring splits the one inside it: the four domains of science, their fields, their subfields. Size is fractional works in 2022-now. Every slice is a page; the interactive view zooms down to single topics and colours each by how much more of it this institution does than the world.

Its 4 domains and 15 fields, with their numbers
    1. Medicine9752.8%
    2. Health Professions00.1%
    3. Dentistry00.0%
    1. Biochemistry, Genetics and Molecular Biology7842.4%
    2. Immunology and Microbiology10.5%
    3. Agricultural and Biological Sciences10.3%
    4. Neuroscience00.1%
    1. Computer Science31.5%
    2. Mathematics10.7%
    3. Engineering10.4%
    4. Environmental Science00.3%
    5. Physics and Astronomy00.1%
    1. Decision Sciences10.4%
    2. Economics, Econometrics and Finance10.4%
    3. Psychology00.1%
All of science, and how each field's share has moved since 1950: the Science domain explorer

What does Guardant (United States) specialise in?

Where its research is concentrated relative to its size: Cancer Research takes 59.8× the share of its output that it takes of world research.

  1. Cancer ResearchSubfield · 47.9 works60×
  2. OncologySubfield · 35.8 works17×
  3. Pulmonary and Respiratory MedicineSubfield · 30.9 works11×
  4. Biochemistry, Genetics and Molecular BiologyField · 78.2 works8.0×
  5. Molecular BiologySubfield · 23.7 works4.3×
← less than its size predicts1×more →

Location quotient, a volume reading rather than an impact one. It surfaces small, lopsided specialities.

Field profile

Location quotient across every field it publishes in: outside the ring is more than an institution of this size would be expected to publish, inside it is less.

Agricultural and Biological Sciences: 0.06× its world share, 0 worksAgricultural and Bio…Biochemistry, Genetics and Molecular Biology: 7.95× its world share, 78 worksBiochemistry, Geneti…Immunology and Microbiology: 0.52× its world share, 1 worksImmunology and Micro…Neuroscience: 0.04× its world share, 0 worksNeuroscienceComputer Science: 0.20× its world share, 3 worksComputer ScienceEngineering: 0.03× its world share, 1 worksEngineeringEnvironmental Science: 0.05× its world share, 0 worksEnvironmental ScienceMathematics: 0.61× its world share, 1 worksMathematicsPhysics and Astronomy: 0.03× its world share, 0 worksPhysics and AstronomyDentistry: 0.06× its world share, 0 worksDentistryHealth Professions: 0.03× its world share, 0 worksHealth ProfessionsMedicine: 2.75× its world share, 97 worksMedicineDecision Sciences: 0.38× its world share, 1 worksDecision SciencesEconomics, Econometrics and Finance: 0.17× its world share, 1 worksEconomics, Econometr…Psychology: 0.03× its world share, 0 worksPsychology1×world share
more than its size predictsabout as predictedless

Rings at 0.5×, 1× and 2×. Widest outward: Biochemistry, Genetics and Molecular Biology, 8.0×. Every wedge is a field page.

All 15 fields, with their numbers
  1. Biochemistry, Genetics and Molecular Biology7.95×78 works
  2. Medicine2.75×97 works
  3. Mathematics0.61×1 works
  4. Immunology and Microbiology0.52×1 works
  5. Decision Sciences0.38×1 works
  6. Computer Science0.20×3 works
  7. Economics, Econometrics and Finance0.17×1 works
  8. Agricultural and Biological Sciences0.06×0 works
  9. Dentistry0.06×0 works
  10. Environmental Science0.05×0 works
  11. Neuroscience0.04×0 works
  12. Engineering0.03×1 works
  13. Physics and Astronomy0.03×0 works
  14. Health Professions0.03×0 works
  15. Psychology0.03×0 works

Who are the top researchers at Guardant (United States)?

Ranked on the quality score, Richard Burnham Lanman, Rebecca J. Nagy and Kimberly C. Banks lead among researchers whose main affiliation is Guardant (United States).

  1. 1 Richard Burnham Lanman United States · #8,390 worldwide 17k citations · 615 works
  2. 2 Rebecca J. Nagy United States · #15,111 worldwide 8k citations · 524 works
  3. 3 Kimberly C. Banks United States · #32,896 worldwide 7.4k citations · 290 works
  4. 4 Justin Iver Odegaard United States · #43,288 worldwide 18k citations · 251 works
  5. 5 Stephen R. Fairclough United States · #78,194 worldwide 4.9k citations · 96 works
  6. 6 AmirAli H. Talasaz United States · #82,583 worldwide 8.7k citations · 279 works
  7. 7 Victoria M. Raymond United States · #106,564 worldwide 9.8k citations · 321 works
  8. 8 Jiemin Liao United States · #152,740 worldwide 4.7k citations · 108 works
  9. 9 Cátálin Bárbácioru United States · #158,025 worldwide 12k citations · 101 works
  10. 10 Oliver A. Zill United States · #162,916 worldwide 3.1k citations · 89 works
All ranked researchers at Guardant (United States)

What are the most cited papers from Guardant (United States)?

The most cited paper from Guardant (United States) is "Comprehensive molecular characterization of clinical responses to PD-1 inhibition in metastatic gastric cancer" (Seung Tae Kim et al., 2018), with 1,755 citations. Next come "Analytical and Clinical Validation of a Digital Sequencing Panel for Quantitative, Highly Accurate Evaluation of Cell-Free Circulating Tumor DNA" (721) and "Clinical Utility of Comprehensive Cell-free DNA Analysis to Identify Genomic Biomarkers in Patients with Newly Diagnosed Metastatic Non–small Cell Lung Cancer" (612).

Most cited papers
#PaperReleasedCitations
1 Comprehensive molecular characterization of clinical responses to PD-1 inhibition in metastatic gastric cancer Seung Tae Kim et al. · Nature Medicine 13 Jul 2018 1,755
2 Analytical and Clinical Validation of a Digital Sequencing Panel for Quantitative, Highly Accurate Evaluation of Cell-Free Circulating Tumor DNA Richard Burnham Lanman, Stefanie Mortimer, Oliver A. Zill et al. · PLoS ONE Open access 16 Oct 2015 721
3 Clinical Utility of Comprehensive Cell-free DNA Analysis to Identify Genomic Biomarkers in Patients with Newly Diagnosed Metastatic Non–small Cell Lung Cancer Natasha B. Leighl, Ray D. Page, Victoria M. Raymond et al. · Clinical Cancer Research 15 Apr 2019 612
4 Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers Collin Michael Blakely et al. · Nature Genetics Open access 6 Nov 2017 597
5 Clinical Acquired Resistance to KRASG12C Inhibition through a Novel KRAS Switch-II Pocket Mutation and Polyclonal Alterations Converging on RAS–MAPK Reactivation Noritaka Tanaka, Jessica J. Lin, Chendi Li et al. · Cancer Discovery Open access 6 Apr 2021 535
All 60 most cited papers, with filters and sorting

Which keywords describe research at Guardant (United States)?

By fractional works in 2022-now, weighted toward what it does more of than the world: Targeted Therapy, Genomic Instability, Somatic Mutations, Cell-Free DNA, Cancer Genomics, Mutational Signatures, Chemotherapy and Clinical Trials.

▲ more of its work than of the world's◆ about the world's share▼ less than the world's

Size is fractional works in 2022-now in the topics tagged with each word; colour is the word's share of this institution's work against its share of the world's. The 40 words are chosen for being large and distinctive. Each links to the topic it comes from most.

All 40 words, with their numbers
  1. Targeted Therapy61▲ 149×4 topics
  2. Genomic Instability45▲ 215×2 topics
  3. Somatic Mutations44▲ 287×2 topics
  4. Cancer Genomics43▲ 328×1 topic
  5. Cell-Free DNA43▲ 242×2 topics
  6. Mutational Signatures43▲ 328×1 topic
  7. Chemotherapy20▲ 16×15 topics
  8. Clinical Trials20▲ 16×6 topics
  9. Genomic Profiling16▲ 87×2 topics
  10. Precision Medicine15▲ 16×5 topics
  11. ALK Inhibitors14▲ 121×1 topic
  12. EGFR Mutations14▲ 121×1 topic
  13. Immunotherapy11▲ 8.1×14 topics
  14. Molecular Characterization11▲ 33×4 topics
  15. Cancer Risk10▲ 25×2 topics
  16. Genetic Testing10▲ 48×2 topics
  17. Cancer10▲ 4.0×17 topics
  18. Breast Cancer10▲ 21×6 topics
  19. Tumor Microenvironment9▲ 11×7 topics
  20. Gene Expression9▲ 7.8×7 topics
  21. Biomarkers8▲ 6.5×7 topics
  22. Adjuvant Chemotherapy8▲ 65×2 topics
  23. Hereditary Syndromes8▲ 140×1 topic
  24. Microsatellite Instability8▲ 140×1 topic
  25. Cell Death7▲ 16×2 topics
  26. Cetuximab7▲ 47×2 topics
  27. Metastasis7▲ 12×7 topics
  28. Molecular Subtypes7▲ 46×3 topics
  29. Prognostic Factors7▲ 8.8×9 topics
  30. Cancer Therapy6▲ 6.2×7 topics
  31. DNA Methylation6▲ 30×1 topic
  32. Histone Modification6▲ 50×1 topic
  33. Predictive Modeling6▲ 12×2 topics
  34. Radiotherapy6▲ 8.5×7 topics
  35. BRAF Mutation6▲ 46×2 topics
  36. Homologous Recombination6▲ 68×2 topics
  37. Fluorouracil6▲ 100×1 topic
  38. KRAS Mutations6▲ 100×1 topic
  39. Metastatic Breast Cancer6▲ 54×2 topics
  40. Quantitative Analysis5▲ 14×1 topic

Which research topics does Guardant (United States) publish most on?

By volume in 2022-now: Cancer Genomics and Diagnostics, Lung Cancer Treatments and Mutations, Genetic factors in colorectal cancer and Epigenetics and DNA Methylation.

Cancer Genomics and Diag…43Cancer Genomics and Diagnostics: 43 fractional worksLung Cancer Treatments and Mutations: 14 fractional worksGenetic factors in colorectal cancer: 8 fractional worksEpigenetics and DNA Methylation: 6 fractional worksColorectal Cancer Treatments and Studies: 6 fractional worksRadiomics and Machine Learning in Medical Imaging: 5 fractional worksAdvanced Breast Cancer Therapies: 5 fractional worksPARP inhibition in cancer therapy: 5 fractional worksCancer Immunotherapy and Biomarkers: 4 fractional worksCancer Diagnosis and Treatment: 3 fractional works
Cancer ResearchPulmonary and Respiratory MedicinePathology and Forensic MedicineMolecular Biology2 others

Area is fractional works; colour is the subfield each topic belongs to.

  1. 1 Cancer Genomics and Diagnostics Cancer Research 43 works
  2. 2 Lung Cancer Treatments and Mutations Pulmonary and Respiratory Medicine 14 works
  3. 3 Genetic factors in colorectal cancer Pathology and Forensic Medicine 8 works
  4. 4 Epigenetics and DNA Methylation Molecular Biology 6 works
  5. 5 Colorectal Cancer Treatments and Studies Oncology 6 works
  6. 6 Radiomics and Machine Learning in Medical Imaging Radiology, Nuclear Medicine and Imaging 5 works
  7. 7 Advanced Breast Cancer Therapies Pulmonary and Respiratory Medicine 5 works
  8. 8 PARP inhibition in cancer therapy Oncology 5 works
  9. 9 Cancer Immunotherapy and Biomarkers Oncology 4 works
  10. 10 Cancer Diagnosis and Treatment Oncology 3 works

How open and international is its research?

Against the world's own shares: the tick on each track. Both are shares of its output, so they sit on one scale and can be read against each other as well as against the world.

openly available27.8%not open72.2%

World: 40% of research is openly available.

with international co-authors19.0%domestic only81.0%

World: 18% is written across borders.

How has Guardant (United States)'s research output changed?

Output in 2022-2025 was 10% higher than in 2018-2021.

still counting200020052010201520202025
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Guardant (United States) as a percentage of every work published that year, 0.00063% in 2024.

still counting0.00050%0.0010%Guardant (United States)0.00082% in 2025200020102020

Fractional works of Guardant (United States) over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year, against all institutions in the same year.

still counting20%40%Guardant (United States)17.3% in 2025all institutions10.0% in 20252020

Of each year's output, the share that reached the world's 10% most cited for its field and year. Peak 30.3% in 2021.

Other research institutions in Redwood City

All research institutions in Redwood City

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Guardant (United States) on Science Explorer

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