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Nephrotoxicity and Medicinal Plants

Nephrotoxicity and Medicinal Plants is a research topic within Radiology, Nuclear Medicine and Imaging. Science Explorer counts 7.3k research works in it since 1950. 10.2% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the health effects associated with aristolochic acid, a compound found in certain Chinese herbs, and its link to nephropathy, urothelial carcinoma, and acute interstitial nephritis. It explores the renal toxicity, mutation signatures, DNA adduct formation, and the potential carcinogenicity of aristolochic acid in herbal remedies.

  • Aristolochic Acid
  • Nephropathy
  • Urothelial Carcinoma
  • Chinese Herb
  • Acute Interstitial Nephritis
  • Renal Toxicity
  • Mutation Signature
  • Environmental Carcinogen
  • DNA Adducts
  • Herbal Remedies
Research works
7.3k
fractional, since 1950
In the world top 10%
740
per year above
Top-10% rate
10.2%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+24%
the tick is no change
Largest producer
China
39% of the 10 largest, 2022-now
Nephrotoxicity and Medicinal Plants

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Nephrotoxicity and Medicinal Plants research?

By volume, China and the United States publish the most (386 and 209 works in 2022-now).

By volume, 2022-now

  1. 1 China 386 works
  2. 2 United States 209 works
  3. 3 India 118 works
  4. 4 Japan 82 works
  5. 5 South Korea 42 works
  6. 6 Germany 34 works
  7. 7 France 31 works
  8. 8 Türkiye 29 works
  9. 9 Spain 28 works
  10. 10 United Kingdom 27 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 39.2%United States: 21.2%India: 11.9%Japan: 8.3%6 others listed: 19.4%39%largest
China386 · 39.2%United States209 · 21.2%India118 · 11.9%Japan82 · 8.3%6 others listed191 · 19.4%

Shares of the rows listed above, not of the whole node.

Which institutions lead Nephrotoxicity and Medicinal Plants research?

By volume in 2022-now, Shanghai University of Traditional Chinese Medicine publishes the most Nephrotoxicity and Medicinal Plants research, followed by Chinese Academy of Medical Sciences & Peking Union Medical College and Yale University.

Who are the leading researchers in Nephrotoxicity and Medicinal Plants?

The most-cited researchers publishing on Nephrotoxicity and Medicinal Plants include Bert Vogelstein, Jun Wang and Giuseppe Remuzzi.

  1. 1 Bert Vogelstein United States 373k citations
  2. 2 Jun Wang China 340k citations
  3. 3 Giuseppe Remuzzi Italy 328k citations
  4. 4 Amirhossein Sahebkar Iran 258k citations
  5. 5 Kenneth W. Kinzler United States 253k citations
  6. 6 Juan Jesús Carrero Sweden 222k citations
  7. 7 Alberto Arduan Ortiz Spain 219k citations
  8. 8 Michael R. Stratton United Kingdom 203k citations
  9. 9 Michael Phillips Australia 199k citations
  10. 10 Rinaldo Bellomo Australia 182k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Nephrotoxicity and Medicinal Plants?

The most cited paper in Nephrotoxicity and Medicinal Plants is "The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety" (Martins Ekor, 2014), with 3,903 citations. Next come "Cisplatin Nephrotoxicity: A Review" (1,259) and "Rapidly progressive interstitial renal fibrosis in young women: association with slimming regimen including Chinese herbs" (1,078).

Most cited papers
#PaperReleasedCitations
1 The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety Martins Ekor · Frontiers in Pharmacology Open access 2014 3,903
2 Cisplatin Nephrotoxicity: A Review Xin Yao, Kessarin Panichpisal, Neil A. Kurtzman et al. · The American Journal of the Medical Sciences Aug 2007 1,259
3 Rapidly progressive interstitial renal fibrosis in young women: association with slimming regimen including Chinese herbs J L Vanherweghem, Christian L. Tielemans, Daniel A. Abramowicz et al. · The Lancet Feb 1993 1,078
4 Tubulointerstitial Changes as a Major Determinant in the Progression of Renal Damage Karl A. Nath · American Journal of Kidney Diseases Jul 1992 984
5 Urothelial Carcinoma Associated with the Use of a Chinese Herb (Aristolochia fangchi) Joëlle Nortier, Marie-Carmen Muniz Martinez, Heinz H. Schmeiser et al. · New England Journal of Medicine Open access 8 Jun 2000 983
All 100 most cited papers, with filters and sorting

Where is Nephrotoxicity and Medicinal Plants research done?

The largest centres of Nephrotoxicity and Medicinal Plants research in 2022-now are Beijing (China), Shanghai (China), Tokyo (Japan) and Guangzhou (China).

Largest cities, 2022-now

  1. 1 BeijingChina 57 works
  2. 2 ShanghaiChina 32 works
  3. 3 TokyoJapan 23 works
  4. 4 GuangzhouChina 23 works
  5. 5 NanjingChina 17 works
  6. 6 SeoulSouth Korea 16 works
  7. 7 ChengduChina 15 works
  8. 8 HangzhouChina 13 works
  9. 9 New YorkUnited States 12 works
  10. 10 ParisFrance 12 works
See Nephrotoxicity and Medicinal Plants on the map

Where is the best place to study Nephrotoxicity and Medicinal Plants?

Among universities, judged by research, Shanghai University of Traditional Chinese Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College and Yale University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Shanghai University of Traditional Chinese MedicineChina 81.620.6%37.6×13 +123.7%
2Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 77.622.1%9.2×12 +32.0%
3Yale UniversityUnited States 20.04.4%8.3×11 +484.2%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Nephrotoxicity and Medicinal Plants, country by country

Is Nephrotoxicity and Medicinal Plants research growing?

Output in 2022-2025 was 24% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Nephrotoxicity and Medicinal Plants.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Nephrotoxicity and Medicinal Plants as a percentage of every work published that year, 0.0062% in 2024.

still counting0.0050%0.010%0.015%Nephrotoxicity and Medicinal Plants0.0060% in 202519801990200020102020

Fractional works of Nephrotoxicity and Medicinal Plants over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Nephrotoxicity and Medicinal Plants10.2% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

Discussion

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