Cytokine Signaling Pathways and Interactions
Cytokine Signaling Pathways and Interactions is a research topic within Oncology. Science Explorer counts 36k research works in it since 1950. 21.8% of them reached the world's top 10% most cited for their field and year.
This cluster of papers focuses on the role of STAT3 in cancer inflammation and immunity, with a particular emphasis on its involvement in cytokine signaling, regulation of the JAK/STAT pathway, modulation of the immune response, and its impact on the tumor microenvironment. The cluster also explores the interplay between STAT3, IL-6, and SOCS proteins in transcriptional control, inflammation, and cancer progression.
- STAT3
- IL-6
- JAK/STAT pathway
- inflammation
- cancer
- cytokine signaling
- immune response
- SOCS proteins
- tumor microenvironment
- transcriptional control
- Research works
- 36k fractional, since 1950
- In the world top 10%
- 7.9k per year above
- Top-10% rate
- 21.8% share of its works in the world top 10%
- Growth, 2013–17 → 2018–22
- -8% the tick is no change
This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.
Which countries lead Cytokine Signaling Pathways and Interactions research?
By volume, China and the United States publish the most (1.5k and 881 works in 2022–2025).
By volume, 2022–2025
- 1 China 1.5k works
- 2 United States 881 works
- 3 Japan 183 works
- 4 India 180 works
- 5 Germany 168 works
- 6 United Kingdom 125 works
- 7 South Korea 123 works
- 8 Italy 113 works
- 9 Egypt 104 works
- 10 Russia 101 works
How concentrated that is
The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.
Shares of the rows listed above, not of the whole node.
Which institutions lead Cytokine Signaling Pathways and Interactions research?
By volume in 2022–2025, Chinese Academy of Medical Sciences & Peking Union Medical College publishes the most Cytokine Signaling Pathways and Interactions research, followed by Nanjing Medical University and The University of Texas MD Anderson Cancer Center.
By volume, 2022–2025
- 1 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 29 works
- 2 Nanjing Medical UniversityChina 19 works
- 3 The University of Texas MD Anderson Cancer CenterUnited States 18 works
- 4 Sun Yat-sen UniversityChina 17 works
- 5 University of North Carolina at Chapel HillUnited States 16 works
- 6 Sichuan UniversityChina 16 works
- 7 Central South UniversityChina 16 works
- 8 Anhui Medical UniversityChina 15 works
- 9 University of BaghdadIraq 14 works
- 10 Cairo UniversityEgypt 14 works
Who are the leading researchers in Cytokine Signaling Pathways and Interactions?
The most-cited researchers publishing on Cytokine Signaling Pathways and Interactions include Alberto Ortíz, Guido Kroemer and Bharat B. Aggarwal.
- 1 Alberto Ortíz Spain 5.9k citations
- 2 Guido Kroemer France 4.2k citations
- 3 Bharat B. Aggarwal United States 4.2k citations
- 4 Michael Karin United States 4k citations
Ranked by citations received across their whole record, among researchers with at least three works on this topic.
Where is Cytokine Signaling Pathways and Interactions research done?
The largest centres of Cytokine Signaling Pathways and Interactions research in 2022–2025 are Beijing (China), Shanghai (China), Guangzhou (China) and Nanjing (China). Among places with at least 20 works in it, it is an unusually large share of all research in Wenzhou.
Largest cities, 2022–2025
Where it is the local speciality
- WenzhouCN · 21.5 works5.5×
Location quotient: how much more of its research is in Cytokine Signaling Pathways and Interactions than the world average.
Where is the best place to study Cytokine Signaling Pathways and Interactions?
Among universities, judged by research, China Pharmaceutical University, Chinese Academy of Medical Sciences & Peking Union Medical College and Zhejiang Chinese Medical University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.
One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.
| # | University | Score | Top 10% | Specialisation | Works | Growth |
|---|---|---|---|---|---|---|
| 1 | China Pharmaceutical UniversityChina | 70.4 | 42.6% | 10.1× | 10 | +145.7% |
| 2 | Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina | 58.9 | 22.8% | 6.7× | 29 | +33.1% |
| 3 | Zhejiang Chinese Medical UniversityChina | 58.7 | 31.2% | 10.7× | 12 | +36.8% |
| 4 | Chengdu University of Traditional Chinese MedicineChina | 56.8 | 30.8% | 10.5× | 10 | — |
| 5 | Guangzhou University of Chinese MedicineChina | 55.9 | 26.5% | 12.2× | 10 | +80.0% |
| 6 | China Medical UniversityChina | 55.7 | 36.4% | 8.5× | 12 | -17.6% |
| 7 | Beijing University of Chinese MedicineChina | 55.4 | 32.4% | 10.7× | 8 | +61.2% |
| 8 | Nanjing University of Chinese MedicineChina | 53.9 | 20.9% | 8.6× | 10 | +263.6% |
| 9 | Anhui Medical UniversityChina | 53.2 | 24.0% | 11.2× | 15 | -31.6% |
| 10 | Wenzhou Medical UniversityChina | 52.9 | 29.0% | 8.0× | 12 | +37.8% |
Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.
Is Cytokine Signaling Pathways and Interactions research growing?
Output in 2018–2022 was 8% lower than in 2013–2017, peaking in 2015. The fastest-growing topics are Cytokine Signaling Pathways and Interactions.
The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.
Which topics inside it are moving
Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.