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Topic · Physiology

Lysosomal Storage Disorders Research

Lysosomal Storage Disorders Research is a research topic within Physiology. Science Explorer counts 22k research works in it since 1950. 17.8% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the diverse aspects of lysosomal storage disorders, including enzyme replacement therapy, genetic mutations, and the impact on various diseases such as Gaucher disease, Fabry disease, Niemann-Pick disease, and Parkinson's disease. It also delves into the underlying mechanisms related to cholesterol metabolism and neuronal ceroid lipofuscinoses.

  • Lysosomal Storage Disorders
  • Enzyme Replacement Therapy
  • Gaucher Disease
  • Fabry Disease
  • Niemann-Pick Disease
  • Parkinson's Disease
  • Glucocerebrosidase Mutations
  • Cholesterol Metabolism
  • Neuronal Ceroid Lipofuscinoses
  • Mucopolysaccharidoses
Research works
22k
fractional, since 1950
In the world top 10%
3.8k
per year above
Top-10% rate
17.8%
share of its works in the world top 10%
Growth, 2013–17 → 2018–22
+13%
the tick is no change

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Lysosomal Storage Disorders Research research?

By volume, the United States and China publish the most (735 and 268 works in 2022–2025).

By volume, 2022–2025

  1. 1 United States 735 works
  2. 2 China 268 works
  3. 3 Italy 215 works
  4. 4 United Kingdom 182 works
  5. 5 Japan 167 works
  6. 6 Brazil 166 works
  7. 7 Germany 153 works
  8. 8 India 128 works
  9. 9 France 111 works
  10. 10 Spain 105 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 33.0%China: 12.0%Italy: 9.6%United Kingdom: 8.2%6 others listed: 37.2%33%largest
United States735 · 33.0%China268 · 12.0%Italy215 · 9.6%United Kingdom182 · 8.2%6 others listed830 · 37.2%

Shares of the rows listed above, not of the whole node.

Which institutions lead Lysosomal Storage Disorders Research research?

By volume in 2022–2025, University College London publishes the most Lysosomal Storage Disorders Research research, followed by Sanofi (United States) and University of Florida.

By volume, 2022–2025

  1. 1 University College LondonUnited Kingdom 22 works
  2. 2 Sanofi (United States)United States 15 works
  3. 3 University of FloridaUnited States 13 works
  4. 4 National Institutes of HealthUnited States 12 works
  5. 5 Universidade Federal do Rio Grande do SulBrazil 12 works
  6. 6 Erasmus MCNetherlands 12 works
  7. 7 University of MinnesotaUnited States 12 works
  8. 8 University of PaduaItaly 11 works
  9. 9 University of MilanItaly 11 works
  10. 10 Duke UniversityUnited States 10 works

Who are the leading researchers in Lysosomal Storage Disorders Research?

The most-cited researchers publishing on Lysosomal Storage Disorders Research include Alberto Ortíz and John Hardy.

  1. 1 Alberto Ortíz Spain 5.9k citations
  2. 2 John Hardy United Kingdom 4k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

Where is Lysosomal Storage Disorders Research research done?

The largest centres of Lysosomal Storage Disorders Research research in 2022–2025 are London (United Kingdom), Paris (France), Beijing (China) and Tokyo (Japan). Among places with at least 20 works in it, it is an unusually large share of all research in Bethesda, Porto Alegre and Durham.

Largest cities, 2022–2025

  1. 1 London United Kingdom 65 works
  2. 2 Paris France 52 works
  3. 3 Beijing China 46 works
  4. 4 Tokyo Japan 45 works
  5. 5 Rome Italy 38 works
  6. 6 Bethesda United States 34 works
  7. 7 São Paulo Brazil 33 works
  8. 8 New York United States 30 works
  9. 9 Madrid Spain 30 works
  10. 10 Milan Italy 28 works

Where it is the local speciality

  1. BethesdaUS · 34.1 works9.1×
  2. Porto AlegreBR · 26.7 works7.8×
  3. DurhamUS · 27.3 works7.4×
← less than its size predictsmore →

Location quotient: how much more of its research is in Lysosomal Storage Disorders Research than the world average.

See Lysosomal Storage Disorders Research on the map

Where is the best place to study Lysosomal Storage Disorders Research?

Among universities, judged by research, University College London, University of Gdańsk and University of Milan score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 15.44%fractional works in this node (log) →share in the world top 10% →University College London: 22, 23.6%University of Gdańsk: 9, 29.3%University of Milan: 11, 18.0%University of Padua: 11, 20.4%Universität Hamburg: 9, 12.9%University of California, Irvine: 9, 6.4%Washington University in St. Louis: 10, 18.7%Duke University: 10, 9.3%Universidade Federal do Rio Grande do Sul: 12, 7.8%University of Florida: 12, 8.0%University of GdańskUniversity College L…University of PaduaUniversity of Milan
above the meannear itbelow it

One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.

#UniversityScoreTop 10%SpecialisationWorksGrowth
1 University College LondonUnited Kingdom 65.423.6%5.2×22 +50.8%
2 University of GdańskPoland 57.929.3%13.2×9 -37.6%
3 University of MilanItaly 44.618.0%5.5×11 +84.9%
4 University of PaduaItaly 40.120.4%4.6×11 -10.3%
5 Universität HamburgGermany 34.612.9%5.4×9 +68.5%
6 University of California, IrvineUnited States 33.96.4%5.4×9 +283.9%
7 Washington University in St. LouisUnited States 33.018.7%4.6×10 -11.4%
8 Duke UniversityUnited States 31.89.3%4.9×10 +100.2%
9 Universidade Federal do Rio Grande do SulBrazil 29.87.8%5.4×12 +32.4%
10 University of FloridaUnited States 29.08.0%4.0×12 +71.4%

Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.

Is Lysosomal Storage Disorders Research research growing?

Output in 2018–2022 was 13% higher than in 2013–2017, peaking in 2025. The fastest-growing topics are Lysosomal Storage Disorders Research.

19801990200020102020
grewheldshrank

The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.