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Topic · Physiology

Syphilis Diagnosis and Treatment

Syphilis Diagnosis and Treatment is a research topic within Physiology. Science Explorer counts 18k research works in it since 1950. 10.3% of them reached the world's top 10% most cited for their field and year.

This cluster of papers covers the biological basis, clinical manifestations, management, and epidemiology of syphilis. It includes topics such as neurosyphilis, syphilis-HIV coinfection, adverse pregnancy outcomes, antibiotic resistance, global epidemiology, point-of-care testing, maternal transmission, ocular manifestations, and immunopathogenesis.

  • Syphilis
  • Neurosyphilis
  • HIV Coinfection
  • Pregnancy Outcomes
  • Antibiotic Resistance
  • Global Epidemiology
  • Point-of-Care Testing
  • Maternal Transmission
  • Ocular Manifestations
  • Immunopathogenesis
Research works
18k
fractional, since 1950
In the world top 10%
1.9k
per year above
Top-10% rate
10.3%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+17%
the tick is no change
Largest producer
Brazil
34% of the 10 largest, 2022-now
Syphilis Diagnosis and Treatment

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Syphilis Diagnosis and Treatment research?

By volume, Brazil and the United States publish the most (947 and 756 works in 2022-now).

By volume, 2022-now

  1. 1 Brazil 947 works
  2. 2 United States 756 works
  3. 3 China 271 works
  4. 4 India 192 works
  5. 5 United Kingdom 146 works
  6. 6 Spain 100 works
  7. 7 Japan 94 works
  8. 8 Australia 91 works
  9. 9 Canada 85 works
  10. 10 Russia 73 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

Brazil: 34.4%United States: 27.4%China: 9.8%India: 7.0%6 others listed: 21.4%34%largest
Brazil947 · 34.4%United States756 · 27.4%China271 · 9.8%India192 · 7.0%6 others listed590 · 21.4%

Shares of the rows listed above, not of the whole node.

Which institutions lead Syphilis Diagnosis and Treatment research?

By volume in 2022-now, United States Department of Health and Human Services publishes the most Syphilis Diagnosis and Treatment research, followed by University of North Carolina at Chapel Hill and Universidade de São Paulo.

By volume, 2022-now

  1. 1 United States Department of Health and Human ServicesUnited States 30 works
  2. 2 University of North Carolina at Chapel HillUnited States 27 works
  3. 3 Universidade de São PauloBrazil 24 works
  4. 4 Secretaria da SaúdeBrazil 21 works
  5. 5 All India Institute of Medical SciencesIndia 21 works
  6. 6 Universidade Federal do CearáBrazil 20 works
  7. 7 University of WashingtonUnited States 19 works
  8. 8 Universidade Federal do Estado do Rio de JaneiroBrazil 19 works
  9. 9 Centro Universitário Fundação Assis GurgaczBrazil 19 works
  10. 10 Universidade TiradentesBrazil 19 works

Who are the leading researchers in Syphilis Diagnosis and Treatment?

The most-cited researchers publishing on Syphilis Diagnosis and Treatment include Simon Iain Hay, George Davey Smith and Jun Wang.

  1. 1 Simon Iain Hay United States 452k citations
  2. 2 George Davey Smith United Kingdom 435k citations
  3. 3 Jun Wang China 340k citations
  4. 4 Matthias Egger Switzerland 326k citations
  5. 5 John P. A. Ioannidis United States 317k citations
  6. 6 Jean‐Louis Vincent Belgium 262k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Syphilis Diagnosis and Treatment?

The most cited paper in Syphilis Diagnosis and Treatment is "From epidemiological synergy to public health policy and practice: the contribution of other sexually transmitted diseases to sexual transmission of HIV infection" (Douglas T. Fleming, Judith N. Wasserheit, 1999), with 2,296 citations. Next come "Sexually transmitted disease surveillance" (2,199) and "Centers for Disease Control and Prevention Sexually Transmitted Diseases Treatment Guidelines" (1,987).

Most cited papers
#PaperReleasedCitations
1 From epidemiological synergy to public health policy and practice: the contribution of other sexually transmitted diseases to sexual transmission of HIV infection Douglas T. Fleming, Judith N. Wasserheit · Sexually Transmitted Infections Open access Feb 1999 2,296
2 Sexually transmitted disease surveillance Brendan H. O’Connor, HilaryE. Tillett, James Berrie et al. · BMJ Open access 13 Mar 1982 2,199
3 Centers for Disease Control and Prevention Sexually Transmitted Diseases Treatment Guidelines Kimberly Workowski, Simeon M. Berman · Clinical Infectious Diseases 3 Mar 2007 1,987
4 Chlamydia, gonorrhoea, trichomoniasis and syphilis: global prevalence and incidence estimates, 2016 Jane T. Rowley, Stephen Vander Hoorn, Eline L. Korenromp et al. · Bulletin of the World Health Organization Open access 6 Jun 2019 1,691
5 Global Estimates of the Prevalence and Incidence of Four Curable Sexually Transmitted Infections in 2012 Based on Systematic Review and Global Reporting Lori Marie Newman, Jane T. Rowley, Stephen Vander Hoorn et al. · PLoS ONE ReviewOpen access 8 Dec 2015 1,658
All 99 most cited papers, with filters and sorting

Where is Syphilis Diagnosis and Treatment research done?

The largest centres of Syphilis Diagnosis and Treatment research in 2022-now are São Paulo (Brazil), Rio de Janeiro (Brazil), London (United Kingdom) and Beijing (China). Among places with at least 20 works in it, it is an unusually large share of all research in Cascavel and Aracaju.

Largest cities, 2022-now

  1. 1 São PauloBrazil 129 works
  2. 2 Rio de JaneiroBrazil 89 works
  3. 3 LondonUnited Kingdom 63 works
  4. 4 BeijingChina 46 works
  5. 5 AtlantaUnited States 42 works
  6. 6 BelémBrazil 39 works
  7. 7 Belo HorizonteBrazil 36 works
  8. 8 FortalezaBrazil 32 works
  9. 9 MadridSpain 31 works
  10. 10 New DelhiIndia 30 works

Where it is the local speciality

  1. CascavelBR · 26.1 works34×
  2. AracajuBR · 27.9 works25×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Syphilis Diagnosis and Treatment than the world average.

See Syphilis Diagnosis and Treatment on the map

Where is the best place to study Syphilis Diagnosis and Treatment?

Among universities, judged by research, University of South China, University of Washington and Universidade Federal do Rio Grande do Norte score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%60%mean 22.04%fractional works in this field (log) →share of work in the world top 10% →University of South …University of Southe…University of Washin…Universidade Federal…
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1University of South ChinaChina 65.155.3%10.8×10 +134.2%
2University of WashingtonUnited States 56.826.0%5.2×20 -21.5%
3Universidade Federal do Rio Grande do NorteBrazil 53.914.5%13.7×17 +58.1%
4University of Southern CaliforniaUnited States 52.835.0%4.3×12 +180.6%
5University of North Carolina at Chapel HillUnited States 51.58.7%4.6×27 -5.2%
6Universidade de São PauloBrazil 50.46.5%3.5×24 +45.8%
7Xiamen UniversityChina 48.724.0%4.3×12 +15.3%
8Universidade Federal do CearáBrazil 48.33.1%13.6×20 +154.9%
9Johns Hopkins UniversityUnited States 47.721.0%3.4×17 -26.0%
10London School of Hygiene & Tropical MedicineUnited Kingdom 47.726.3%17.2×9 -36.6%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Syphilis Diagnosis and Treatment, country by country

Is Syphilis Diagnosis and Treatment research growing?

Output in 2022-2025 was 17% higher than in 2018-2021, peaking in 2024. The fastest-growing topics are Syphilis Diagnosis and Treatment.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Syphilis Diagnosis and Treatment as a percentage of every work published that year, 0.017% in 2024.

still counting0.020%0.040%Syphilis Diagnosis and Treatment0.015% in 202519801990200020102020

Fractional works of Syphilis Diagnosis and Treatment over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Syphilis Diagnosis and Treatment10.4% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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