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Topic · Physiology

Adipose Tissue and Metabolism

Adipose Tissue and Metabolism is a research topic within Physiology. Science Explorer counts 81k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the function and physiological significance of brown adipose tissue, including its role in thermogenesis, the involvement of PGC-1a and UCP1, mitochondrial dysfunction, insulin resistance, beige adipocytes, metabolic regulation, and the impact of exercise on brown adipose tissue. The papers also explore the molecular mechanisms underlying adaptive thermogenesis and the potential therapeutic implications for metabolic disorders.

  • Brown Adipose Tissue
  • Thermogenesis
  • PGC-1a
  • Mitochondrial Dysfunction
  • Insulin Resistance
  • Beige Adipocytes
  • Metabolic Regulation
  • Exercise
  • UCP1
  • Adaptive Thermogenesis
Research works
81k
fractional, since 1950
In the world top 10%
8k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+2%
the tick is no change
Largest producer
United States
34% of the 10 largest, 2022-now
Adipose Tissue and Metabolism

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Adipose Tissue and Metabolism research?

By volume, the United States and China publish the most (2.8k and 2.6k works in 2022-now).

By volume, 2022-now

  1. 1 United States 2.8k works
  2. 2 China 2.6k works
  3. 3 Japan 518 works
  4. 4 Germany 375 works
  5. 5 Brazil 340 works
  6. 6 South Korea 338 works
  7. 7 Canada 337 works
  8. 8 India 324 works
  9. 9 Italy 320 works
  10. 10 Iran 287 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 34.2%China: 31.5%Japan: 6.3%Germany: 4.5%6 others listed: 23.5%34%largest
United States2,832 · 34.2%China2,602 · 31.5%Japan518 · 6.3%Germany375 · 4.5%6 others listed1,946 · 23.5%

Shares of the rows listed above, not of the whole node.

Which institutions lead Adipose Tissue and Metabolism research?

By volume in 2022-now, Harvard University publishes the most Adipose Tissue and Metabolism research, followed by Russian Academy of Sciences and Chinese Academy of Sciences.

By volume, 2022-now

  1. 1 Harvard UniversityUnited States 108 works
  2. 2 Russian Academy of SciencesRussia 91 works
  3. 3 Chinese Academy of SciencesChina 62 works
  4. 4 InsermFrance 60 works
  5. 5 Islamic Azad University, TehranIran 60 works
  6. 6 Centre National de la Recherche ScientifiqueFrance 57 works
  7. 7 Shanghai Jiao Tong UniversityChina 54 works
  8. 8 National Institutes of HealthUnited States 52 works
  9. 9 Chinese Academy of Agricultural SciencesChina 47 works
  10. 10 Universidade de São PauloBrazil 44 works

Who are the leading researchers in Adipose Tissue and Metabolism?

The most-cited researchers publishing on Adipose Tissue and Metabolism include Eric S. Lander, Rob Knight and George Davey Smith.

  1. 1 Eric S. Lander United States 524k citations
  2. 2 Rob Knight United States 468k citations
  3. 3 George Davey Smith United Kingdom 435k citations
  4. 4 Walter Churchill Willett United States 411k citations
  5. 5 Stacey L. Gabriel United States 402k citations
  6. 6 Guido Kroemer France 386k citations
  7. 7 John J.V. McMurray United Kingdom 349k citations
  8. 8 Hermann Brenner Germany 343k citations
  9. 9 Shizuo Akira Japan 342k citations
  10. 10 Cyrus Cooper United Kingdom 342k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Adipose Tissue and Metabolism?

The most cited paper in Adipose Tissue and Metabolism is "Positional cloning of the mouse obese gene and its human homologue" (Yiying Zhang, Ricardo Proenca, Margherita Maffei et al., 1994), with 13,483 citations. Next come "Inflammation and metabolic disorders" (9,214) and "Biochemistry and molecular cell biology of diabetic complications" (9,153).

Most cited papers
#PaperReleasedCitations
1 Positional cloning of the mouse obese gene and its human homologue Yiying Zhang, Ricardo Proenca, Margherita Maffei et al. · Nature Dec 1994 13,483
2 Inflammation and metabolic disorders Gökhan S. Hotamışlıgil · Nature 13 Dec 2006 9,214
3 Biochemistry and molecular cell biology of diabetic complications Michael Brownlee · Nature 13 Dec 2001 9,153
4 Obesity is associated with macrophage accumulation in adipose tissue Stuart Phillip Weisberg, Daniel McCann, Manisha Desai et al. · Journal of Clinical Investigation Open access 15 Dec 2003 8,604
5 The Metabolic Phenotype in Obesity: Fat Mass, Body Fat Distribution, and Adipose Tissue Function Gijs H. Goossens · Obesity Facts Open access 2017 8,505
All 98 most cited papers, with filters and sorting

Where is Adipose Tissue and Metabolism research done?

The largest centres of Adipose Tissue and Metabolism research in 2022-now are Beijing (China), Shanghai (China), Guangzhou (China) and Tokyo (Japan). Among places with at least 20 works in it, it is an unusually large share of all research in Ya'an and Baton Rouge.

Largest cities, 2022-now

  1. 1 BeijingChina 365 works
  2. 2 ShanghaiChina 201 works
  3. 3 GuangzhouChina 146 works
  4. 4 TokyoJapan 141 works
  5. 5 SeoulSouth Korea 134 works
  6. 6 NanjingChina 126 works
  7. 7 ParisFrance 122 works
  8. 8 WuhanChina 101 works
  9. 9 MoscowRussia 94 works
  10. 10 TehranIran 92 works

Where it is the local speciality

  1. Ya'anCN · 31.4 works9.7×
  2. Baton RougeUS · 35.7 works8.0×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Adipose Tissue and Metabolism than the world average.

See Adipose Tissue and Metabolism on the map

Where is the best place to study Adipose Tissue and Metabolism?

Among universities, judged by research, Harvard University, Shanghai University of Sport and Johns Hopkins University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%30%mean 19.75%fractional works in this field (log) →share of work in the world top 10% →Wuhan UniversityShanghai University …Harvard UniversityJohns Hopkins Univer…
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Harvard UniversityUnited States 87.418.1%3.3×108 +14.5%
2Shanghai University of SportChina 66.124.1%33.9×19 +70.7%
3Johns Hopkins UniversityUnited States 64.811.1%2.6×41 +35.5%
4Wuhan UniversityChina 61.825.3%2.0×29 +19.2%
5Chengdu University of Traditional Chinese MedicineChina 61.427.9%4.5×12 +436.5%
6Central South UniversityChina 61.220.2%1.9×36 +49.8%
7Fudan UniversityChina 60.417.9%2.4×38 +30.1%
8Karolinska InstitutetSweden 60.115.8%5.3×31 -3.4%
9Sichuan UniversityChina 59.518.8%1.8×41 +69.3%
10Southern Medical UniversityChina 58.118.3%4.6×29 +69.9%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Adipose Tissue and Metabolism, country by country

Is Adipose Tissue and Metabolism research growing?

Output in 2022-2025 was 2% higher than in 2018-2021, peaking in 2024. The fastest-growing topics are Adipose Tissue and Metabolism.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Adipose Tissue and Metabolism as a percentage of every work published that year, 0.053% in 2024.

still counting0.10%0.20%Adipose Tissue and Metabolism0.048% in 202519801990200020102020

Fractional works of Adipose Tissue and Metabolism over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Adipose Tissue and Metabolism9.9% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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