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Topic · Physiology

Erythrocyte Function and Pathophysiology

Erythrocyte Function and Pathophysiology is a research topic within Physiology. Science Explorer counts 48k research works in it since 1950. 10.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the role of mechanosensitive ion channels, particularly Piezo1 and Piezo2, in various physiological processes such as mechanotransduction, erythrocyte function, sensory neuron response, and erythropoiesis. It also explores the implications of these channels in diseases related to erythrocytes, sensory perception, and cellular mechanosensation.

  • Piezo1
  • Piezo2
  • mechanotransduction
  • erythrocyte
  • mechanosensation
  • ion channels
  • membrane
  • sensory neurons
  • erythropoiesis
  • apoptosis
Research works
48k
fractional, since 1950
In the world top 10%
4.8k
per year above
Top-10% rate
10.0%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+7%
the tick is no change
Largest producer
United States
35% of the 10 largest, 2022-now
Erythrocyte Function and Pathophysiology

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Erythrocyte Function and Pathophysiology research?

By volume, the United States and China publish the most (1.3k and 892 works in 2022-now).

By volume, 2022-now

  1. 1 United States 1.3k works
  2. 2 China 892 works
  3. 3 India 315 works
  4. 4 Japan 217 works
  5. 5 Germany 204 works
  6. 6 Italy 180 works
  7. 7 France 175 works
  8. 8 United Kingdom 158 works
  9. 9 Russia 155 works
  10. 10 Canada 95 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 34.9%China: 24.3%India: 8.6%Japan: 5.9%6 others listed: 26.3%35%largest
United States1,280 · 34.9%China892 · 24.3%India315 · 8.6%Japan217 · 5.9%6 others listed967 · 26.3%

Shares of the rows listed above, not of the whole node.

Which institutions lead Erythrocyte Function and Pathophysiology research?

By volume in 2022-now, Russian Academy of Sciences publishes the most Erythrocyte Function and Pathophysiology research, followed by Harvard University and Centre National de la Recherche Scientifique.

By volume, 2022-now

  1. 1 Russian Academy of SciencesRussia 53 works
  2. 2 Harvard UniversityUnited States 44 works
  3. 3 Centre National de la Recherche ScientifiqueFrance 38 works
  4. 4 National Institutes of HealthUnited States 34 works
  5. 5 InsermFrance 33 works
  6. 6 Shanghai Jiao Tong UniversityChina 25 works
  7. 7 Sichuan UniversityChina 25 works
  8. 8 Chinese Academy of SciencesChina 25 works
  9. 9 Zhejiang UniversityChina 25 works
  10. 10 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 24 works

Who are the leading researchers in Erythrocyte Function and Pathophysiology?

The most-cited researchers publishing on Erythrocyte Function and Pathophysiology include George Davey Smith, Guido Kroemer and Shizuo Akira.

  1. 1 George Davey Smith United Kingdom 435k citations
  2. 2 Guido Kroemer France 386k citations
  3. 3 Shizuo Akira Japan 342k citations
  4. 4 Giuseppe Remuzzi Italy 328k citations
  5. 5 Gregory Y.H. Lip United Kingdom 311k citations
  6. 6 Matthias Mann Germany 308k citations
  7. 7 Róbert Langer United States 303k citations
  8. 8 Gonçalo R. Abecasis United States 300k citations
  9. 9 Richard A. Gibbs United States 292k citations
  10. 10 Luigi Ferrucci United States 281k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Erythrocyte Function and Pathophysiology?

The most cited paper in Erythrocyte Function and Pathophysiology is "Mutation of the mouse klotho gene leads to a syndrome resembling ageing." (M Kuro-o, Y Matsumura, H Aizawa et al., 1997), with 66,570 citations. Next come "Functional rafts in cell membranes" (9,793) and "The Warburg Effect: How Does it Benefit Cancer Cells?" (5,355).

Most cited papers
#PaperReleasedCitations
1 Mutation of the mouse klotho gene leads to a syndrome resembling ageing. M Kuro-o, Y Matsumura, H Aizawa et al. · PubMed 6 Nov 1997 66,570
2 Functional rafts in cell membranes Kai Simons, Elina Ikonen · Nature Jun 1997 9,793
3 The Warburg Effect: How Does it Benefit Cancer Cells? Maria V. Liberti, Jason W. Locasale · Trends in Biochemical Sciences ReviewOpen access 5 Jan 2016 5,355
4 The preparation and chemical characteristics of hemoglobin-free ghosts of human erythrocytes James T. Dodge, Carolyn D. Mitchell, Donald J. Hanahan · Archives of Biochemistry and Biophysics 1963 4,421
5 Mutation of the mouse klotho gene leads to a syndrome resembling ageing Makoto Kuro‐o, Yutaka Matsumura, Hiroki Aizawa et al. · Nature 6 Nov 1997 3,876
All 100 most cited papers, with filters and sorting

Where is Erythrocyte Function and Pathophysiology research done?

The largest centres of Erythrocyte Function and Pathophysiology research in 2022-now are Beijing (China), Paris (France), Shanghai (China) and Guangzhou (China). Among places with at least 20 works in it, it is an unusually large share of all research in Bethesda.

Largest cities, 2022-now

  1. 1 BeijingChina 125 works
  2. 2 ParisFrance 88 works
  3. 3 ShanghaiChina 71 works
  4. 4 GuangzhouChina 68 works
  5. 5 MoscowRussia 68 works
  6. 6 New YorkUnited States 58 works
  7. 7 TokyoJapan 54 works
  8. 8 LondonUnited Kingdom 46 works
  9. 9 HangzhouChina 41 works
  10. 10 PhiladelphiaUnited States 38 works

Where it is the local speciality

  1. BethesdaUS · 35.3 works6.0×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Erythrocyte Function and Pathophysiology than the world average.

See Erythrocyte Function and Pathophysiology on the map

Where is the best place to study Erythrocyte Function and Pathophysiology?

Among universities, judged by research, Harvard University, Sun Yat-sen University and Sichuan University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 23.3%fractional works in this field (log) →share of work in the world top 10% →Zhejiang UniversitySun Yat-sen UniversitySichuan UniversityHarvard University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Harvard UniversityUnited States 70.614.6%3.2×44 -3.0%
2Sun Yat-sen UniversityChina 64.224.5%2.7×24 +101.8%
3Sichuan UniversityChina 63.524.3%2.6×25 +176.5%
4Zhejiang UniversityChina 63.124.8%2.1×25 +88.4%
5Wuhan UniversityChina 61.135.3%1.9×12 +108.4%
6Shanghai Jiao Tong UniversityChina 59.424.0%2.0×26 +24.6%
7University of LeedsUnited Kingdom 56.329.4%4.3×11 +32.3%
8University of California San DiegoUnited States 54.514.5%3.9×16 +24.4%
9Peking UniversityChina 52.521.1%2.0×18 +51.1%
10University of PennsylvaniaUnited States 52.520.5%3.6×16 +3.7%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Erythrocyte Function and Pathophysiology, country by country

Is Erythrocyte Function and Pathophysiology research growing?

Output in 2022-2025 was 7% higher than in 2018-2021, peaking in 2022. The fastest-growing topics are Erythrocyte Function and Pathophysiology.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Erythrocyte Function and Pathophysiology as a percentage of every work published that year, 0.021% in 2024.

still counting0.10%0.20%Erythrocyte Function and Pathophysiology0.019% in 202519801990200020102020

Fractional works of Erythrocyte Function and Pathophysiology over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Erythrocyte Function and Pathophysiology10.2% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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