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Topic · Pulmonary and Respiratory Medicine

Silymarin and Mushroom Poisoning

Silymarin and Mushroom Poisoning is a research topic within Pulmonary and Respiratory Medicine. Science Explorer counts 6.6k research works in it since 1950. 10.1% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the use of silymarin, a flavonolignan complex derived from milk thistle, in the treatment of liver diseases, including hepatitis and hepatocellular carcinoma. It explores silymarin's hepatoprotective and antioxidant effects, its potential as a supportive treatment in liver diseases, its role in cancer treatment and chemoprevention, as well as its pharmacokinetics and toxicity.

  • Silymarin
  • Liver Diseases
  • Hepatoprotective
  • Antioxidant
  • Cancer Treatment
  • Pharmacokinetics
  • Milk Thistle
  • Hepatitis C
  • Chemoprevention
  • Toxicity
Research works
6.6k
fractional, since 1950
In the world top 10%
673
per year above
Top-10% rate
10.1%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+41%
the tick is no change
Largest producer
China
32% of the 10 largest, 2022-now
Silymarin and Mushroom Poisoning

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Silymarin and Mushroom Poisoning research?

By volume, China and India publish the most (446 and 302 works in 2022-now).

By volume, 2022-now

  1. 1 China 446 works
  2. 2 India 302 works
  3. 3 Iran 143 works
  4. 4 United States 142 works
  5. 5 Türkiye 91 works
  6. 6 Egypt 80 works
  7. 7 South Korea 58 works
  8. 8 Italy 46 works
  9. 9 Iraq 41 works
  10. 10 Japan 41 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 32.1%India: 21.7%Iran: 10.3%United States: 10.2%6 others listed: 25.7%32%largest
China446 · 32.1%India302 · 21.7%Iran143 · 10.3%United States142 · 10.2%6 others listed357 · 25.7%

Shares of the rows listed above, not of the whole node.

Which institutions lead Silymarin and Mushroom Poisoning research?

By volume in 2022-now, Islamic Azad University, Tehran publishes the most Silymarin and Mushroom Poisoning research, followed by Chinese Academy of Sciences and Mashhad University of Medical Sciences.

By volume, 2022-now

  1. 1 Islamic Azad University, TehranIran 17 works
  2. 2 Chinese Academy of SciencesChina 12 works
  3. 3 Mashhad University of Medical SciencesIran 10 works
  4. 4 Chinese Academy of Agricultural SciencesChina 9 works
  5. 5 Russian Academy of SciencesRussia 9 works
  6. 6 Tabriz University of Medical SciencesIran 9 works
  7. 7 Hindu College of PharmacyIndia 9 works
  8. 8 Tehran University of Medical SciencesIran 8 works
  9. 9 Chengdu University of Traditional Chinese MedicineChina 7 works
  10. 10 King Saud UniversitySaudi Arabia 7 works

Who are the leading researchers in Silymarin and Mushroom Poisoning?

The most-cited researchers publishing on Silymarin and Mushroom Poisoning include Reza Malekzadeh, Amirhossein Sahebkar and Edward L. Giovannucci.

  1. 1 Reza Malekzadeh Iran 278k citations
  2. 2 Amirhossein Sahebkar Iran 258k citations
  3. 3 Edward L. Giovannucci United States 219k citations
  4. 4 Barry B. Halliwell United Kingdom 179k citations
  5. 5 Félix Dias Carvalho Portugal 174k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Silymarin and Mushroom Poisoning?

The most cited paper in Silymarin and Mushroom Poisoning is "ACETYLORNITHINASE OF ESCHERICHIA COLI: PARTIAL PURIFICATION AND SOME PROPERTIES" (Henry J. Vogel, David M. Bonner, 1956), with 4,027 citations. Next come "Regorafenib for patients with hepatocellular carcinoma who progressed on sorafenib treatment (RESORCE): a randomised, double-blind, placebo-controlled, phase 3 trial" (3,732) and "Effect of Selenium and Vitamin E on Risk of Prostate Cancer and Other Cancers" (2,136).

Most cited papers
#PaperReleasedCitations
1 ACETYLORNITHINASE OF ESCHERICHIA COLI: PARTIAL PURIFICATION AND SOME PROPERTIES Henry J. Vogel, David M. Bonner · Journal of Biological Chemistry Open access 1956 4,027
2 Regorafenib for patients with hepatocellular carcinoma who progressed on sorafenib treatment (RESORCE): a randomised, double-blind, placebo-controlled, phase 3 trial Jordi Bruix et al. · The Lancet Open access 5 Dec 2016 3,732
3 Effect of Selenium and Vitamin E on Risk of Prostate Cancer and Other Cancers Scott Michael Lippman et al. · JAMA Open access 9 Dec 2008 2,136
4 What is the True Solubility Advantage for Amorphous Pharmaceuticals? Bruno C. Hancock, Michael Parks · Pharmaceutical Research Apr 2000 1,352
5 Palifermin for Oral Mucositis after Intensive Therapy for Hematologic Cancers Ricardo Tomas Spielberger, Patrick J. Stiff, William Bensinger et al. · New England Journal of Medicine 15 Dec 2004 902
All 100 most cited papers, with filters and sorting

Where is Silymarin and Mushroom Poisoning research done?

The largest centres of Silymarin and Mushroom Poisoning research in 2022-now are Beijing (China), Tehran (Iran), Guangzhou (China) and Shanghai (China). Among places with at least 20 works in it, it is an unusually large share of all research in Kunming.

Largest cities, 2022-now

  1. 1 BeijingChina 55 works
  2. 2 TehranIran 44 works
  3. 3 GuangzhouChina 26 works
  4. 4 ShanghaiChina 24 works
  5. 5 KunmingChina 23 works
  6. 6 CairoEgypt 19 works
  7. 7 NanjingChina 18 works
  8. 8 ChengduChina 18 works
  9. 9 New DelhiIndia 18 works
  10. 10 ChennaiIndia 17 works

Where it is the local speciality

  1. KunmingCN · 22.9 works5.4×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Silymarin and Mushroom Poisoning than the world average.

See Silymarin and Mushroom Poisoning on the map

Where is the best place to study Silymarin and Mushroom Poisoning?

Among universities, judged by research, Tabriz University of Medical Sciences, Mashhad University of Medical Sciences and Islamic Azad University, Tehran score highest, combining citation excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%mean 12.64%fractional works in this field (log) →share of work in the world top 10% →Tabriz University of…Mashhad University o…Tehran University of…Islamic Azad Univers…
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Citation excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Tabriz University of Medical SciencesIran 74.622.7%19.2×9 +46.8%
2Mashhad University of Medical SciencesIran 54.214.3%24.0×10 +9.1%
3Islamic Azad University, TehranIran 45.510.8%5.9×17 +2.0%
4Tehran University of Medical SciencesIran 29.911.3%7.8×8 -1.9%
5Hindu College of PharmacyIndia 22.94.1%48.0×9 +102.8%

Universities only. The score blends citation excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Silymarin and Mushroom Poisoning, country by country

Is Silymarin and Mushroom Poisoning research growing?

Output in 2022-2025 was 41% higher than in 2018-2021, peaking in 2026. The fastest-growing topics are Silymarin and Mushroom Poisoning.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Silymarin and Mushroom Poisoning as a percentage of every work published that year, 0.0060% in 2024.

still counting0.0050%0.010%Silymarin and Mushroom Poisoning0.0094% in 202519801990200020102020

Fractional works of Silymarin and Mushroom Poisoning over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Silymarin and Mushroom Poisoning10.4% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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