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Topic · Pulmonary and Respiratory Medicine

Cystic Fibrosis Research Advances

Cystic Fibrosis Research Advances is a research topic within Pulmonary and Respiratory Medicine. Science Explorer counts 30k research works in it since 1950. 10.1% of them reached the world's top 10% most cited for their field and year.

This cluster of papers encompasses a wide range of topics related to cystic fibrosis, including therapeutic interventions, pulmonary infections, bronchiectasis, primary ciliary dyskinesia, mutation analysis, lung disease, microbiota, and nutrition management. The papers cover advancements in understanding the genetic and molecular basis of cystic fibrosis, as well as the development of novel treatments and management strategies.

  • Cystic Fibrosis
  • CFTR
  • Pulmonary Infections
  • Bronchiectasis
  • Primary Ciliary Dyskinesia
  • Mutation Analysis
  • Lung Disease
  • Microbiota
  • Nutrition Management
  • Therapeutic Interventions
Research works
30k
fractional, since 1950
In the world top 10%
3k
per year above
Top-10% rate
10.1%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+30%
the tick is no change
Largest producer
United States
38% of the 10 largest, 2022-now
Cystic Fibrosis Research Advances

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Cystic Fibrosis Research Advances research?

By volume, the United States and the United Kingdom publish the most (1.9k and 750 works in 2022-now).

By volume, 2022-now

  1. 1 United States 1.9k works
  2. 2 United Kingdom 750 works
  3. 3 China 461 works
  4. 4 Italy 378 works
  5. 5 Germany 324 works
  6. 6 France 272 works
  7. 7 Australia 235 works
  8. 8 Canada 227 works
  9. 9 Türkiye 206 works
  10. 10 Spain 196 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 38.5%United Kingdom: 15.1%China: 9.3%Italy: 7.6%6 others listed: 29.5%38%largest
United States1,907 · 38.5%United Kingdom750 · 15.1%China461 · 9.3%Italy378 · 7.6%6 others listed1,461 · 29.5%

Shares of the rows listed above, not of the whole node.

Which institutions lead Cystic Fibrosis Research Advances research?

By volume in 2022-now, University of North Carolina at Chapel Hill publishes the most Cystic Fibrosis Research Advances research, followed by University of Alabama at Birmingham and Harvard University.

By volume, 2022-now

  1. 1 University of North Carolina at Chapel HillUnited States 87 works
  2. 2 University of Alabama at BirminghamUnited States 65 works
  3. 3 Harvard UniversityUnited States 56 works
  4. 4 University of TorontoCanada 53 works
  5. 5 Emory UniversityUnited States 48 works
  6. 6 Johns Hopkins UniversityUnited States 47 works
  7. 7 InsermFrance 46 works
  8. 8 University of WashingtonUnited States 41 works
  9. 9 University of CincinnatiUnited States 41 works
  10. 10 Russian Academy of SciencesRussia 41 works

Who are the leading researchers in Cystic Fibrosis Research Advances?

The most-cited researchers publishing on Cystic Fibrosis Research Advances include Rob Knight, Guido Kroemer and Zulfiqar Ahmed Bhutta.

  1. 1 Rob Knight United States 468k citations
  2. 2 Guido Kroemer France 386k citations
  3. 3 Zulfiqar Ahmed Bhutta Pakistan 371k citations
  4. 4 Jun Wang China 340k citations
  5. 5 Gregory Y.H. Lip United Kingdom 311k citations
  6. 6 Róbert Langer United States 303k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Cystic Fibrosis Research Advances?

The most cited paper in Cystic Fibrosis Research Advances is "Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA" (John R. Riordan, Johanna M. Rommens, Bat-Sheva Kerem et al., 1989), with 7,480 citations. Next come "Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis" (4,999) and "Standardization of Spirometry 2019 Update. An Official American Thoracic Society and European Respiratory Society Technical Statement" (4,326).

Most cited papers
#PaperReleasedCitations
1 Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA John R. Riordan, Johanna M. Rommens, Bat-Sheva Kerem et al. · Science 8 Sep 1989 7,480
2 Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis Laurent Meijer et al. · Journal of Innate Immunity Open access 2016 4,999
3 Standardization of Spirometry 2019 Update. An Official American Thoracic Society and European Respiratory Society Technical Statement Brian L. Graham, Irene Steenbruggen, Martin R. Miller et al. · American Journal of Respiratory and Critical Care Medicine Open access Oct 2019 4,326
4 Identification of the Cystic Fibrosis Gene: Genetic Analysis Bat-Sheva Kerem, Johanna M. Rommens, Janet A. Buchanan et al. · Science 8 Sep 1989 4,164
5 Combination of 16S rRNA-targeted oligonucleotide probes with flow cytometry for analyzing mixed microbial populations Rudolf Amann, Brian J. Binder, Robert Olson et al. · Applied and Environmental Microbiology Open access Jun 1990 4,069
All 99 most cited papers, with filters and sorting

Where is Cystic Fibrosis Research Advances research done?

The largest centres of Cystic Fibrosis Research Advances research in 2022-now are London (United Kingdom), Paris (France), Moscow (Russia) and Chapel Hill (United States). Among places with at least 20 works in it, it is an unusually large share of all research in Verona, Birmingham and Dundee.

Largest cities, 2022-now

  1. 1 LondonUnited Kingdom 194 works
  2. 2 ParisFrance 127 works
  3. 3 MoscowRussia 92 works
  4. 4 Chapel HillUnited States 86 works
  5. 5 TorontoCanada 77 works
  6. 6 AnkaraTürkiye 71 works
  7. 7 BostonUnited States 71 works
  8. 8 BirminghamUnited States 70 works
  9. 9 BeijingChina 67 works
  10. 10 MilanItaly 66 works

Where it is the local speciality

  1. VeronaIT · 34.4 works20×
  2. BirminghamUS · 69.5 works18×
  3. DundeeGB · 26.6 works17×
  4. GiessenDE · 35.1 works14×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Cystic Fibrosis Research Advances than the world average.

See Cystic Fibrosis Research Advances on the map

Where is the best place to study Cystic Fibrosis Research Advances?

Among universities, judged by research, University of Dundee, Humanitas University and University of Washington score highest, combining citation excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 17%fractional works in this field (log) →share of work in the world top 10% →University of DundeeHumanitas UniversityImperial College Lon…University of Washin…
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Citation excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1University of DundeeUnited Kingdom 79.430.0%24.5×26 +25.8%
2Humanitas UniversityItaly 70.625.4%14.9×13 +480.4%
3University of WashingtonUnited States 66.111.8%6.0×42 +38.5%
4Imperial College LondonUnited Kingdom 65.616.1%5.7×34 +29.7%
5Utrecht UniversityNetherlands 64.518.3%6.2×27 +49.5%
6University of GroningenNetherlands 63.623.9%4.5×19 +39.8%
7University of CopenhagenDenmark 62.913.7%5.1×29 +63.1%
8University of Alabama at BirminghamUnited States 62.86.3%22.1×65 +57.9%
9Harvard UniversityUnited States 62.812.2%2.9×56 +5.2%
10University of Colorado DenverUnited States 61.712.3%15.2×30 +53.2%

Universities only. The score blends citation excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Cystic Fibrosis Research Advances, country by country

Is Cystic Fibrosis Research Advances research growing?

Output in 2022-2025 was 30% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Cystic Fibrosis Research Advances.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Cystic Fibrosis Research Advances as a percentage of every work published that year, 0.028% in 2024.

still counting0.020%0.040%0.060%Cystic Fibrosis Research Advances0.030% in 202519801990200020102020

Fractional works of Cystic Fibrosis Research Advances over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Cystic Fibrosis Research Advances10.3% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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