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Company · Sheffield · United Kingdom

Simcyp (United Kingdom)

In research, Simcyp (United Kingdom) stands highest in Health Sciences (#6,327 of 16,688 worldwide) and Medicine (#5,642 of 14,558 worldwide), over all time.

ROR OpenAlex
World rank, 2022-now
#20,898
of 22,385 · #19,139 all time
Rank in United Kingdom
#784
of 862
Research works
256
▼ 6% vs 2018-21
Citations
9.6k
37.4 per fractional work
Top-10% rate
18.2%
all institutions 10.0%
vs its own fields
1.14×
1.00× is exactly expected
Open access
61%
world 40%
International
53%
world 18%
Simcyp (United Kingdom)

What is Simcyp (United Kingdom) known for in research?

The fields where it stands highest, over all time, ranked among every institution above the floor in each field.

FieldWorld rankWhere that sitsTop-10% rateWorks
Health SciencesDomain #6,327 of 16,688 24.0%125
MedicineField #5,642 of 14,558 24.4%122

Each strip is that field's whole ranked pool, with the notch where Simcyp (United Kingdom) sits in it, in the colour of the band that rank falls in. The track under the rate is the rate itself: it carries no average mark, because the average differs by field (from about 6% in Dentistry to 21% in Economics).

Which fields of science does Simcyp (United Kingdom) work in?

In 2022-now, 51% of research at Simcyp (United Kingdom) is in Health Sciences, 33% in Life Sciences. Its largest fields are Medicine (49%), Pharmacology, Toxicology and Pharmaceutics (16%), Biochemistry, Genetics and Molecular Biology (14%). It does 2.2× the world's share of Life Sciences.

Health Sciences: 39 fractional works · 51.2% of its workMedicine: 37 fractional works · 48.7% of its workPediatrics, Perinatology and Child Health: 6 fractional works · 7.6% of its workOncology: 5 fractional works · 6.6% of its workEpidemiology: 4 fractional works · 5.4% of its workPublic Health, Environmental and Occupational Health: 4 fractional works · 5.2% of its workPulmonary and Respiratory Medicine: 2 fractional works · 3.2% of its workPharmacology: 2 fractional works · 2.7% of its workCardiology and Cardiovascular Medicine: 2 fractional works · 2.4% of its workRadiology, Nuclear Medicine and Imaging: 2 fractional works · 2.4% of its workObstetrics and Gynecology: 1 fractional works · 1.4% of its workGenetics: 1 fractional works · 1.3% of its workDermatology: 1 fractional works · 1.3% of its workHepatology: 1 fractional works · 1.2% of its workHematology: 1 fractional works · 1.2% of its workInfectious Diseases: 1 fractional works · 1.1% of its workGastroenterology: 1 fractional works · 0.8% of its workPsychiatry and Mental health: 1 fractional works · 0.8% of its workSurgery: 1 fractional works · 0.7% of its workNephrology: 0 fractional works · 0.6% of its workRheumatology: 0 fractional works · 0.6% of its workPhysiology: 0 fractional works · 0.5% of its workEndocrinology, Diabetes and Metabolism: 0 fractional works · 0.5% of its workTransplantation: 0 fractional works · 0.4% of its workGeriatrics and Gerontology: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.5% of its workVeterinary: 1 fractional works · 1.8% of its workSmall Animals: 1 fractional works · 1.8% of its workNursing: 0 fractional works · 0.7% of its workNutrition and Dietetics: 0 fractional works · 0.7% of its workLife Sciences: 25 fractional works · 33.0% of its workPharmacology, Toxicology and Pharmaceutics: 12 fractional works · 15.5% of its workPharmacology: 9 fractional works · 11.1% of its workPharmaceutical Science: 3 fractional works · 3.5% of its workToxicology: 1 fractional works · 0.9% of its workBiochemistry, Genetics and Molecular Biology: 11 fractional works · 14.4% of its workMolecular Biology: 7 fractional works · 9.4% of its workGenetics: 2 fractional works · 3.1% of its workCancer Research: 1 fractional works · 0.8% of its workBiochemistry: 0 fractional works · 0.6% of its workBiophysics: 0 fractional works · 0.3% of its workClinical Biochemistry: 0 fractional works · 0.3% of its workAgricultural and Biological Sciences: 1 fractional works · 1.3% of its workFood Science: 0 fractional works · 0.6% of its workPlant Science: 0 fractional works · 0.5% of its workInsect Science: 0 fractional works · 0.2% of its workImmunology and Microbiology: 1 fractional works · 1.2% of its workImmunology: 1 fractional works · 1.0% of its workSmaller subfields together: 0 fractional works · 0.2% of its workNeuroscience: 0 fractional works · 0.6% of its workCellular and Molecular Neuroscience: 0 fractional works · 0.5% of its workSmaller subfields together: 0 fractional works · 0.0% of its workPhysical Sciences: 11 fractional works · 13.7% of its workMathematics: 3 fractional works · 4.3% of its workStatistics and Probability: 3 fractional works · 4.3% of its workChemistry: 2 fractional works · 3.3% of its workSpectroscopy: 2 fractional works · 2.2% of its workAnalytical Chemistry: 0 fractional works · 0.5% of its workInorganic Chemistry: 0 fractional works · 0.4% of its workSmaller subfields together: 0 fractional works · 0.1% of its workComputer Science: 2 fractional works · 2.9% of its workComputational Theory and Mathematics: 2 fractional works · 2.8% of its workSmaller subfields together: 0 fractional works · 0.1% of its workEngineering: 1 fractional works · 1.7% of its workBiomedical Engineering: 1 fractional works · 1.6% of its workSmaller subfields together: 0 fractional works · 0.1% of its workEnvironmental Science: 1 fractional works · 1.5% of its workHealth, Toxicology and Mutagenesis: 1 fractional works · 1.4% of its workSmaller subfields together: 0 fractional works · 0.1% of its workMaterials Science: 0 fractional works · 0.0% of its workSocial Sciences: 2 fractional works · 2.2% of its workDecision Sciences: 1 fractional works · 1.3% of its workStatistics, Probability and Uncertainty: 1 fractional works · 1.3% of its workEconomics, Econometrics and Finance: 1 fractional works · 0.7% of its workEconomics and Econometrics: 1 fractional works · 0.7% of its workPsychology: 0 fractional works · 0.2% of its workALL ITS WORKSimcyp (UnitedKingdom)77fractional works, 2022-now
Life Sciences33%Physical Sciences14%Health Sciences51%Social Sciences2%

Each ring splits the one inside it: the four domains of science, their fields, their subfields. Size is fractional works in 2022-now. Every slice is a page; the interactive view zooms down to single topics and colours each by how much more of it this institution does than the world.

Its 4 domains and 17 fields, with their numbers
    1. Medicine3748.7%
    2. Veterinary11.8%
    3. Nursing00.7%
    1. Pharmacology, Toxicology and Pharmaceutics1215.5%
    2. Biochemistry, Genetics and Molecular Biology1114.4%
    3. Agricultural and Biological Sciences11.3%
    4. Immunology and Microbiology11.2%
    5. Neuroscience00.6%
    1. Mathematics34.3%
    2. Chemistry23.3%
    3. Computer Science22.9%
    4. Engineering11.7%
    5. Environmental Science11.5%
    6. Materials Science00.0%
    1. Decision Sciences11.3%
    2. Economics, Econometrics and Finance10.7%
    3. Psychology00.2%
All of science, and how each field's share has moved since 1950: the Science domain explorer

Field profile

Location quotient across every field it publishes in: outside the ring is more than an institution of this size would be expected to publish, inside it is less.

Agricultural and Biological Sciences: 0.27× its world share, 1 worksAgricultural and Bio…Biochemistry, Genetics and Molecular Biology: 2.70× its world share, 11 worksBiochemistry, Geneti…Immunology and Microbiology: 1.16× its world share, 1 worksImmunology and Micro…Neuroscience: 0.36× its world share, 0 worksNeurosciencePharmacology, Toxicology and Pharmaceutics: 44.01× its world share, 12 worksPharmacology, Toxico…Chemistry: 2.07× its world share, 2 worksChemistryComputer Science: 0.38× its world share, 2 worksComputer ScienceEngineering: 0.11× its world share, 1 worksEngineeringEnvironmental Science: 0.30× its world share, 1 worksEnvironmental ScienceMaterials Science: 0.01× its world share, 0 worksMaterials ScienceMathematics: 3.67× its world share, 3 worksMathematicsMedicine: 2.53× its world share, 38 worksMedicineNursing: 1.33× its world share, 0 worksNursingVeterinary: 13.22× its world share, 1 worksVeterinaryDecision Sciences: 1.35× its world share, 1 worksDecision SciencesEconomics, Econometrics and Finance: 0.32× its world share, 0 worksEconomics, Econometr…Psychology: 0.06× its world share, 0 worksPsychology1×world share
more than its size predictsabout as predictedless

Rings at 0.5×, 1× and 2×. Widest outward: Pharmacology, Toxicology and Pharmaceutics, 44.0×. Every wedge is a field page.

All 17 fields, with their numbers
  1. Pharmacology, Toxicology and Pharmaceutics44.01×12 works
  2. Veterinary13.22×1 works
  3. Mathematics3.67×3 works
  4. Biochemistry, Genetics and Molecular Biology2.70×11 works
  5. Medicine2.53×38 works
  6. Chemistry2.07×2 works
  7. Decision Sciences1.35×1 works
  8. Nursing1.33×0 works
  9. Immunology and Microbiology1.16×1 works
  10. Computer Science0.38×2 works
  11. Neuroscience0.36×0 works
  12. Economics, Econometrics and Finance0.32×0 works
  13. Environmental Science0.30×1 works
  14. Agricultural and Biological Sciences0.27×1 works
  15. Engineering0.11×1 works
  16. Psychology0.06×0 works
  17. Materials Science0.01×0 works

Who are the top researchers at Simcyp (United Kingdom)?

Ranked on the quality score, Trevor N. Johnson, Masoud Jamei and Khaled Abduljalil lead among researchers whose main affiliation is Simcyp (United Kingdom).

  1. 1 Trevor N. Johnson United Kingdom · #210,049 worldwide 5.2k citations · 119 works
  2. 2 Masoud Jamei United Kingdom · #444,032 worldwide 9.1k citations · 193 works
  3. 3 Khaled Abduljalil United Kingdom · #540,928 worldwide 2.4k citations · 66 works
  4. 4 Amita Pansari United Kingdom · #649,467 worldwide 496 citations · 21 works
  5. 5 Lisa M. Almond United Kingdom · #803,547 worldwide 1.6k citations · 45 works
  6. 6 Sibylle Neuhoff United Kingdom · #803,631 worldwide 4.3k citations · 115 works
  7. 7 Karen Rowland Yeo United Kingdom · #845,505 worldwide 3.1k citations · 83 works
  8. 8 K Rowland‐Yeo United Kingdom · #913,346 worldwide 2.1k citations · 39 works
  9. 9 Jiansong Yang United Kingdom · #1,264,298 worldwide 2.1k citations · 26 works
  10. 10 Peter J. Kilford United Kingdom · #1,411,329 worldwide 760 citations · 16 works
All ranked researchers at Simcyp (United Kingdom)

What are the most cited papers from Simcyp (United Kingdom)?

The most cited paper from Simcyp (United Kingdom) is "Physiologically-Based Pharmacokinetics in Drug Development and Regulatory Science" (Malcolm Rowland, Carl C. Peck, Geoffrey T. Tucker, 2011), with 656 citations. Next come "Basic Concepts in Physiologically Based Pharmacokinetic Modeling in Drug Discovery and Development" (615) and "Simulation and prediction of in vivo drug metabolism in human populations from in vitro data" (532).

Most cited papers
#PaperReleasedCitations
1 Physiologically-Based Pharmacokinetics in Drug Development and Regulatory Science Malcolm Rowland, Carl C. Peck, Geoffrey T. Tucker · The Annual Review of Pharmacology and Toxicology Review 6 Jan 2011 656
2 Basic Concepts in Physiologically Based Pharmacokinetic Modeling in Drug Discovery and Development HM Jones, K Rowland‐Yeo · CPT Pharmacometrics & Systems Pharmacology Open access Aug 2013 615
3 Simulation and prediction of in vivo drug metabolism in human populations from in vitro data Amin Rostami‐Hodjegan, Geoffrey T. Tucker · Nature Reviews Drug Discovery Review Feb 2007 532
4 The Simcyp ® Population-based ADME Simulator Masoud Jamei, Steve Marciniak, Kairui Feng et al. · Expert Opinion on Drug Metabolism & Toxicology Feb 2009 530
5 Prediction of the Clearance of Eleven Drugs and Associated Variability in Neonates, Infants and Children Trevor N. Johnson, Amin Rostami‐Hodjegan, Geoffrey T. Tucker · Clinical Pharmacokinetics 2006 527
All 60 most cited papers, with filters and sorting

Which keywords describe research at Simcyp (United Kingdom)?

By fractional works in 2022-now, weighted toward what it does more of than the world: Pharmacokinetics, Cytochrome P450, Genetic Variation, Drug Metabolism, Pharmacogenetics, Teratogenicity, Inflammatory Bowel Disease and Adverse Drug Reactions.

▲ more of its work than of the world's◆ about the world's share▼ less than the world's

Size is fractional works in 2022-now in the topics tagged with each word; colour is the word's share of this institution's work against its share of the world's. The 40 words are chosen for being large and distinctive. Each links to the topic it comes from most.

All 40 words, with their numbers
  1. Pharmacokinetics10▲ 50×3 topics
  2. Cytochrome P4508▲ 325×2 topics
  3. Genetic Variation8▲ 48×3 topics
  4. Drug Metabolism8▲ 378×1 topic
  5. Pharmacogenetics8▲ 512×1 topic
  6. Teratogenicity5▲ 116×2 topics
  7. Inflammatory Bowel Disease4▲ 45×4 topics
  8. Oxidative Stress4▲ 3.2×14 topics
  9. Adverse Drug Reactions4▲ 94×2 topics
  10. Clinical Trials4▲ 7.5×3 topics
  11. Drug Development4▲ 55×2 topics
  12. Medication Adherence4▲ 86×2 topics
  13. Nuclear Receptors4▲ 53×2 topics
  14. Biomarkers4▲ 6.6×5 topics
  15. Off-Label Drug Use4▲ 178×1 topic
  16. Pediatric Pharmacokinetics4▲ 178×1 topic
  17. ATP-dependent Transporters3▲ 176×1 topic
  18. Multidrug Resistance3▲ 128×1 topic
  19. Immunosuppressive Drugs3▲ 67×2 topics
  20. Pregnancy3▲ 20×2 topics
  21. Rheumatoid Arthritis3▲ 41×2 topics
  22. Birth Outcomes3▲ 156×1 topic
  23. Medication Use3▲ 156×1 topic
  24. Metabolic Syndrome3▲ 4.6×8 topics
  25. Monoclonal Antibodies3▲ 42×3 topics
  26. Therapeutic Antibodies3▲ 53×2 topics
  27. Bayesian Methods3▲ 67×2 topics
  28. Medicinal Chemistry2▲ 12×3 topics
  29. Adaptive Designs2▲ 137×1 topic
  30. False Discovery Rate2▲ 137×1 topic
  31. Molecular Docking2▲ 23×1 topic
  32. Virtual Screening2▲ 31×1 topic
  33. Antiepileptic Drugs2▲ 36×2 topics
  34. Fetal Development2▲ 28×2 topics
  35. Glycosylation2▲ 25×3 topics
  36. Neurodevelopmental Disorders2▲ 20×2 topics
  37. Cognitive Function2▲ 13×1 topic
  38. Prenatal Exposure2▲ 81×1 topic
  39. NAFLD2▲ 19×1 topic
  40. NASH2▲ 19×1 topic

Which research topics does Simcyp (United Kingdom) publish most on?

By volume in 2022-now: Pharmacogenetics and Drug Metabolism, Pharmaceutical studies and practices, Drug Transport and Resistance Mechanisms and Pregnancy and Medication Impact.

Pharmacogenetics and Dru…8Pharmacogenetics and Drug Metabolism: 8 fractional worksPharmaceutical studies a…4Pharmaceutical studies and practices: 4 fractional worksDrug Transport and Resis…3Drug Transport and Resistance Mechanisms: 3 fractional worksPregnancy and Medication Impact: 3 fractional worksComputational Drug Discovery Methods: 2 fractional worksStatistical Methods in C…2Statistical Methods in Clinical Trials: 2 fractional worksPharmacological Effects and Toxicity Studies: 2 fractional worksLiver Disease Diagnosis and Treatment: 2 fractional worksMonoclonal and Polyclonal Antibodies Research: 2 fractional worksProtein purification and stability: 1 fractional works
PharmacologyPediatrics, Perinatology and Child HealthOncologyPublic Health, Environmental and Occupational Health5 others

Area is fractional works; colour is the subfield each topic belongs to.

  1. 1 Pharmacogenetics and Drug Metabolism Pharmacology 8 works
  2. 2 Pharmaceutical studies and practices Pediatrics, Perinatology and Child Health 4 works
  3. 3 Drug Transport and Resistance Mechanisms Oncology 3 works
  4. 4 Pregnancy and Medication Impact Public Health, Environmental and Occupational Health 3 works
  5. 5 Computational Drug Discovery Methods Computational Theory and Mathematics 2 works
  6. 6 Statistical Methods in Clinical Trials Statistics and Probability 2 works
  7. 7 Pharmacological Effects and Toxicity Studies Pediatrics, Perinatology and Child Health 2 works
  8. 8 Liver Disease Diagnosis and Treatment Epidemiology 2 works
  9. 9 Monoclonal and Polyclonal Antibodies Research Radiology, Nuclear Medicine and Imaging 2 works
  10. 10 Protein purification and stability Molecular Biology 1 works

How open and international is its research?

Against the world's own shares: the tick on each track. Both are shares of its output, so they sit on one scale and can be read against each other as well as against the world.

openly available61.1%not open38.9%

World: 40% of research is openly available.

with international co-authors52.8%domestic only47.2%

World: 18% is written across borders.

How has Simcyp (United Kingdom)'s research output changed?

Output in 2022-2025 was 6% lower than in 2018-2021.

still counting20052010201520202025
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Simcyp (United Kingdom) as a percentage of every work published that year, 0.00031% in 2024.

still counting0.00025%0.00050%0.00075%Simcyp (United Kingdom)0.00012% in 202520102020

Fractional works of Simcyp (United Kingdom) over all fractional works that year. How the balance of science has shifted.

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Simcyp (United Kingdom) on Science Explorer

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