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Topic · Organic Chemistry

Advanced Synthetic Organic Chemistry

Advanced Synthetic Organic Chemistry is a research topic within Organic Chemistry. Science Explorer counts 9.6k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the advances in amide chemistry and synthesis, including chemoselective reactions, reductive functionalization, and iridium-catalyzed transformations. It also explores the synthesis of pyridine derivatives and Stemona alkaloids through total synthesis and chemical transformations.

  • Amides
  • Chemoselective Synthesis
  • Alkaloids
  • Reductive Functionalization
  • Iridium-Catalyzed Reactions
  • Pyridine Derivatives
  • Stemona Alkaloids
  • Total Synthesis
  • Chemical Transformations
  • Nucleophilic Addition
Research works
9.6k
fractional, since 1950
In the world top 10%
948
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+0%
the tick is no change
Largest producer
China
45% of the 10 largest, 2022-now
Advanced Synthetic Organic Chemistry

Which countries lead Advanced Synthetic Organic Chemistry research?

By volume, China and the United States publish the most (340 and 112 works in 2022-now).

By volume, 2022-now

  1. 1 China 340 works
  2. 2 United States 112 works
  3. 3 India 85 works
  4. 4 Japan 65 works
  5. 5 Germany 37 works
  6. 6 United Kingdom 28 works
  7. 7 France 26 works
  8. 8 Russia 26 works
  9. 9 South Korea 19 works
  10. 10 Spain 14 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 45.2%United States: 14.9%India: 11.3%Japan: 8.7%6 others listed: 20.0%45%largest
China340 · 45.2%United States112 · 14.9%India85 · 11.3%Japan65 · 8.7%6 others listed150 · 20.0%

Shares of the rows listed above, not of the whole node.

Which institutions lead Advanced Synthetic Organic Chemistry research?

By volume in 2022-now, Chinese Academy of Sciences publishes the most Advanced Synthetic Organic Chemistry research, followed by Centre National de la Recherche Scientifique and Russian Academy of Sciences.

By volume, 2022-now

  1. 1 Chinese Academy of SciencesChina 31 works
  2. 2 Centre National de la Recherche ScientifiqueFrance 14 works
  3. 3 Russian Academy of SciencesRussia 13 works
  4. 4 Lanzhou UniversityChina 9 works
  5. 5 Sun Yat-sen UniversityChina 7 works
  6. 6 University of Chinese Academy of SciencesChina 7 works
  7. 7 Council of Scientific and Industrial ResearchIndia 7 works
  8. 8 Xiamen UniversityChina 7 works
  9. 9 Nankai UniversityChina 7 works
  10. 10 University of North Carolina at Chapel HillUnited States 6 works

Who are the leading researchers in Advanced Synthetic Organic Chemistry?

The most-cited researchers publishing on Advanced Synthetic Organic Chemistry include Xiaogang Wang, Stefan Grimme and George M. Sheldrick.

  1. 1 Xiaogang Wang China 260k citations
  2. 2 Stefan Grimme Germany 224k citations
  3. 3 George M. Sheldrick Germany 220k citations
  4. 4 L. Li France 211k citations
  5. 5 Hua Zhang Singapore 196k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Advanced Synthetic Organic Chemistry?

The most cited paper in Advanced Synthetic Organic Chemistry is "Amide bond formation: beyond the myth of coupling reagents" (Eric Valeur, Mark Bradley, 2008), with 2,203 citations. Next come "Rethinking amide bond synthesis" (2,162) and "Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?" (2,040).

Most cited papers
#PaperReleasedCitations
1 Amide bond formation: beyond the myth of coupling reagents Eric Valeur, Mark Bradley · Chemical Society Reviews Review 4 Dec 2008 2,203
2 Rethinking amide bond synthesis Vijaya Raghavan Pattabiraman, Jeffrey W. Bode · Nature Dec 2011 2,162
3 Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone? Dean G. Brown, Jonas Boström · Journal of Medicinal Chemistry Open access 16 Nov 2015 2,040
4 N-methoxy-n-methylamides as effective acylating agents Steven H. Nahm, Steven M. Weinreb · Tetrahedron Letters 1981 1,798
5 Amide bond formation and peptide coupling Christian Montalbetti, Virginie M. Falque · Tetrahedron 20 Sep 2005 1,773
All 100 most cited papers, with filters and sorting

Where is Advanced Synthetic Organic Chemistry research done?

The largest centres of Advanced Synthetic Organic Chemistry research in 2022-now are Beijing (China), Shanghai (China), Tokyo (Japan) and Hangzhou (China).

Largest cities, 2022-now

  1. 1 BeijingChina 48 works
  2. 2 ShanghaiChina 30 works
  3. 3 TokyoJapan 21 works
  4. 4 HangzhouChina 17 works
  5. 5 GuangzhouChina 15 works
  6. 6 ChengduChina 14 works
  7. 7 TianjinChina 13 works
  8. 8 LanzhouChina 12 works
  9. 9 NanjingChina 12 works
  10. 10 ShenzhenChina 11 works
See Advanced Synthetic Organic Chemistry on the map

Where is the best place to study Advanced Synthetic Organic Chemistry?

Among universities, judged by research, Lanzhou University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Lanzhou UniversityChina 2.99.4%15.7×8 -8.4%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Advanced Synthetic Organic Chemistry, country by country

Is Advanced Synthetic Organic Chemistry research growing?

Output in 2022-2025 was 0% higher than in 2018-2021, peaking in 2014. The fastest-growing topics are Advanced Synthetic Organic Chemistry.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Advanced Synthetic Organic Chemistry as a percentage of every work published that year, 0.0029% in 2024.

still counting0.010%0.020%0.030%Advanced Synthetic Organic Chemistry0.0038% in 202519801990200020102020

Fractional works of Advanced Synthetic Organic Chemistry over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Advanced Synthetic Organic Chemistry10.2% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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