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Topic · Physiology

Alzheimer's disease research and treatments

Alzheimer's disease research and treatments is a research topic within Physiology. Science Explorer counts 59k research works in it since 1950. 30.5% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the research and mechanisms related to Alzheimer's disease, including the amyloid hypothesis, tau pathology, protein misfolding, neuroinflammation, synaptic dysfunction, oxidative stress, genetic associations, Aß oligomers, neurodegeneration, and therapeutic strategies.

  • Amyloid Hypothesis
  • Tau Pathology
  • Protein Misfolding
  • Neuroinflammation
  • Synaptic Dysfunction
  • Oxidative Stress
  • Genetic Association
  • Aß Oligomers
  • Neurodegeneration
  • Therapeutic Strategies
Research works
59k
fractional, since 1950
In the world top 10%
18k
per year above
Top-10% rate
30.5%
share of its works in the world top 10%
Growth, 2013–17 → 2018–22
+26%
the tick is no change

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Alzheimer's disease research and treatments research?

By volume, the United States and China publish the most (3.7k and 2.2k works in 2022–2025).

By volume, 2022–2025

  1. 1 United States 3.7k works
  2. 2 China 2.2k works
  3. 3 India 732 works
  4. 4 United Kingdom 571 works
  5. 5 Japan 450 works
  6. 6 Italy 401 works
  7. 7 South Korea 395 works
  8. 8 Germany 379 works
  9. 9 Canada 366 works
  10. 10 Spain 347 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 38.8%China: 23.0%India: 7.7%United Kingdom: 6.0%6 others listed: 24.5%39%largest
United States3,696 · 38.8%China2,195 · 23.0%India732 · 7.7%United Kingdom571 · 6.0%6 others listed2,339 · 24.5%

Shares of the rows listed above, not of the whole node.

Which institutions lead Alzheimer's disease research and treatments research?

By volume in 2022–2025, Harvard University publishes the most Alzheimer's disease research and treatments research, followed by University College London and Washington University in St. Louis.

By volume, 2022–2025

  1. 1 Harvard University United States 73 works
  2. 2 University College London United Kingdom 72 works
  3. 3 Washington University in St. Louis United States 67 works
  4. 4 University of Pennsylvania United States 65 works
  5. 5 University of Pittsburgh United States 62 works
  6. 6 Massachusetts General Hospital United States 61 works
  7. 7 University of California, San Francisco United States 60 works
  8. 8 University of California, Irvine United States 58 works
  9. 9 UK Dementia Research Institute United Kingdom 50 works
  10. 10 University of Gothenburg Sweden 49 works

Who are the leading researchers in Alzheimer's disease research and treatments?

The most-cited researchers publishing on Alzheimer's disease research and treatments include Mika Kivimäki, Josef Coresh and Luigi Ferrucci.

  1. 1 Mika Kivimäki 6.7k citations
  2. 2 Josef Coresh 5.3k citations
  3. 3 Luigi Ferrucci 5.3k citations
  4. 4 John C. Morris 5.1k citations
  5. 5 Perminder S. Sachdev 4.6k citations
  6. 6 André G. Uitterlinden 4.4k citations
  7. 7 R. J. Wilson 4.2k citations
  8. 8 John Hardy 4k citations
  9. 9 Ronald C. Petersen 4k citations
  10. 10 Carol Brayne 3.9k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

Where is Alzheimer's disease research and treatments research done?

The largest centres of Alzheimer's disease research and treatments research in 2022–2025 are Beijing (China), London (United Kingdom), Seoul (South Korea) and Shanghai (China). Among places with at least 20 works in it, it is an unusually large share of all research in Indianapolis.

Largest cities, 2022–2025

  1. 1 Beijing China 317 works
  2. 2 London United Kingdom 271 works
  3. 3 Seoul South Korea 193 works
  4. 4 Shanghai China 190 works
  5. 5 New York United States 183 works
  6. 6 Boston United States 182 works
  7. 7 Tokyo Japan 130 works
  8. 8 Paris France 128 works
  9. 9 Guangzhou China 118 works
  10. 10 Philadelphia United States 111 works

Where it is the local speciality

  1. Indianapolis34.7 works18×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Alzheimer's disease research and treatments than the world average.

See Alzheimer's disease research and treatments on the map

Where is the best place to study Alzheimer's disease research and treatments?

Among universities, judged by research, Central University of Punjab, University of Gothenburg and University College London score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%25%50%mean 35.15%fractional works in this node (log) →share in the world top 10% →Central University of Punjab: 12, 59.3%University of Gothenburg: 49, 25.1%University College London: 72, 35.2%Texas Tech University Health Sciences Center: 12, 45.5%Karolinska Institutet: 42, 33.8%University Memory and Aging Center: 21, 24.6%Heilongjiang University of Chinese Medicine: 11, 34.8%Indiana University – Purdue University Indianapolis: 44, 24.3%University of California, San Francisco: 60, 28.1%Jamia Hamdard: 10, 40.8%Central University o…Texas Tech Universit…University College L…University of Gothen…
above the meannear itbelow it

One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.

#UniversityScoreTop 10%SpecialisationWorksGrowth
1Central University of Punjab India 66.959.3%13.4×12 —
2University of Gothenburg Sweden 63.925.1%10.4×49 +22.8%
3University College London United Kingdom 61.935.2%4.4×72 +83.6%
4Texas Tech University Health Sciences Center United States 61.345.5%9.6×12 +113.7%
5Karolinska Institutet Sweden 60.833.8%8.0×42 -31.3%
6University Memory and Aging Center United States 60.624.6%166.2×21 +87.2%
7Heilongjiang University of Chinese Medicine China 60.134.8%13.4×11 +248.5%
8Indiana University – Purdue University Indianapolis United States 60.024.3%12.1×44 +36.6%
9University of California, San Francisco United States 59.628.1%8.0×60 +26.3%
10Jamia Hamdard India 58.440.8%8.9×10 +124.8%

Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.

Is Alzheimer's disease research and treatments research growing?

Output in 2018–2022 was 26% higher than in 2013–2017, peaking in 2025. The fastest-growing topics are Alzheimer's disease research and treatments.

19801990200020102020
grewheldshrank

The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.