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Topic · Organic Chemistry

Axial and Atropisomeric Chirality Synthesis

Axial and Atropisomeric Chirality Synthesis is a research topic within Organic Chemistry. Science Explorer counts 11k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the atroposelective synthesis of axially chiral compounds, exploring topics such as atropisomerism, asymmetric synthesis, catalytic reactions, enantioselective methods, and the use of chiral ligands. The research covers various techniques including Suzuki-Miyaura coupling, oxidative coupling, and organocatalysis.

  • Atropisomerism
  • Axial Chirality
  • Asymmetric Synthesis
  • Biaryl Compounds
  • Catalytic Reactions
  • Enantioselective
  • Organocatalysis
  • Suzuki-Miyaura Coupling
  • Oxidative Coupling
  • Chiral Ligands
Research works
11k
fractional, since 1950
In the world top 10%
1.1k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+28%
the tick is no change
Largest producer
China
55% of the 10 largest, 2022-now
Axial and Atropisomeric Chirality Synthesis

Which countries lead Axial and Atropisomeric Chirality Synthesis research?

By volume, China and Japan publish the most (611 and 115 works in 2022-now).

By volume, 2022-now

  1. 1 China 611 works
  2. 2 Japan 115 works
  3. 3 United States 101 works
  4. 4 India 78 works
  5. 5 Germany 58 works
  6. 6 France 48 works
  7. 7 United Kingdom 27 works
  8. 8 Spain 27 works
  9. 9 Russia 26 works
  10. 10 Italy 22 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 54.8%Japan: 10.4%United States: 9.0%India: 7.0%6 others listed: 18.8%55%largest
China611 · 54.8%Japan115 · 10.4%United States101 · 9.0%India78 · 7.0%6 others listed209 · 18.8%

Shares of the rows listed above, not of the whole node.

Which institutions lead Axial and Atropisomeric Chirality Synthesis research?

By volume in 2022-now, Chinese Academy of Sciences publishes the most Axial and Atropisomeric Chirality Synthesis research, followed by Centre National de la Recherche Scientifique and Sichuan University.

By volume, 2022-now

  1. 1 Chinese Academy of SciencesChina 52 works
  2. 2 Centre National de la Recherche ScientifiqueFrance 25 works
  3. 3 Sichuan UniversityChina 20 works
  4. 4 Southern University of Science and TechnologyChina 17 works
  5. 5 Russian Academy of SciencesRussia 15 works
  6. 6 Zhengzhou UniversityChina 15 works
  7. 7 Henan Normal UniversityChina 13 works
  8. 8 Zhejiang UniversityChina 12 works
  9. 9 University of Chinese Academy of SciencesChina 12 works
  10. 10 Qingdao UniversityChina 11 works

Who are the leading researchers in Axial and Atropisomeric Chirality Synthesis?

The most-cited researchers publishing on Axial and Atropisomeric Chirality Synthesis include Richard A. Gibbs, George M. Whitesides and Wei Huang.

  1. 1 Richard A. Gibbs United States 292k citations
  2. 2 George M. Whitesides United States 267k citations
  3. 3 Wei Huang China 267k citations
  4. 4 Ben Zhong Tang China 261k citations
  5. 5 Stefan Grimme Germany 224k citations
  6. 6 Kai You Wang China 224k citations
  7. 7 George M. Sheldrick Germany 220k citations
  8. 8 John Anthony Pople United States 202k citations
  9. 9 William A. Goddard United States 182k citations
  10. 10 Kläus Müllen Germany 182k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Axial and Atropisomeric Chirality Synthesis?

The most cited paper in Axial and Atropisomeric Chirality Synthesis is "New Strategies for Organic Catalysis: The First Highly Enantioselective Organocatalytic Diels−Alder Reaction" (Kateri A. Ahrendt, Christopher J. Borths, David W. C. MacMillan, 2000), with 1,690 citations. Next come "Recent Advances in the Baylis−Hillman Reaction and Applications" (1,604) and "Helicenes: Synthesis and Applications" (1,545).

Most cited papers
#PaperReleasedCitations
1 New Strategies for Organic Catalysis: The First Highly Enantioselective Organocatalytic Diels−Alder Reaction Kateri A. Ahrendt, Christopher J. Borths, David W. C. MacMillan · Journal of the American Chemical Society 15 Apr 2000 1,690
2 Recent Advances in the Baylis−Hillman Reaction and Applications Deevi Basavaiah, Anumolu Jaganmohan Rao, Tummanapalli Satyanarayana · Chemical Reviews Review 27 Feb 2003 1,604
3 Helicenes: Synthesis and Applications Yun Hwei Shen, Chuan‐Feng Chen · Chemical Reviews Review 24 Oct 2011 1,545
4 Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products Gerhard Bringmann, Tanja Gulder, Tobias A. M. Gulder et al. · Chemical Reviews Review 12 Oct 2010 1,442
5 Enantioselective Michael Reaction of Malonates to Nitroolefins Catalyzed by Bifunctional Organocatalysts Tomotaka Okino, Yasutaka Hoashi, Yoshiji Takemoto · Journal of the American Chemical Society 30 Sep 2003 1,422
All 97 most cited papers, with filters and sorting

Where is Axial and Atropisomeric Chirality Synthesis research done?

The largest centres of Axial and Atropisomeric Chirality Synthesis research in 2022-now are Beijing (China), Shanghai (China), Hangzhou (China) and Tokyo (Japan). Among places with at least 20 works in it, it is an unusually large share of all research in Hefei and Shenzhen.

Largest cities, 2022-now

  1. 1 BeijingChina 72 works
  2. 2 ShanghaiChina 59 works
  3. 3 HangzhouChina 37 works
  4. 4 TokyoJapan 36 works
  5. 5 ChengduChina 34 works
  6. 6 NanjingChina 27 works
  7. 7 HefeiChina 27 works
  8. 8 ShenzhenChina 25 works
  9. 9 ZhengzhouChina 19 works
  10. 10 GuangzhouChina 18 works

Where it is the local speciality

  1. HefeiCN · 26.6 works5.8×
  2. ShenzhenCN · 24.6 works5.8×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Axial and Atropisomeric Chirality Synthesis than the world average.

See Axial and Atropisomeric Chirality Synthesis on the map

Where is the best place to study Axial and Atropisomeric Chirality Synthesis?

Among universities, judged by research, Southern University of Science and Technology, ShanghaiTech University and Qingdao University score highest, combining citation excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 28.1%fractional works in this field (log) →share of work in the world top 10% →ShanghaiTech Univers…Qingdao UniversityZhengzhou UniversitySouthern University …
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Citation excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Southern University of Science and TechnologyChina 77.718.4%29.1×17 +32.9%
2ShanghaiTech UniversityChina 66.339.8%41.3×8 +333.3%
3Qingdao UniversityChina 64.733.2%14.5×11 +239.6%
4Zhengzhou UniversityChina 64.329.7%11.0×15 +151.6%
5Henan Normal UniversityChina 56.725.6%59.7×13 +930.2%
6Sichuan UniversityChina 49.410.8%7.9×20 +148.6%
7Chongqing UniversityChina 46.824.8%6.8×8 +10.4%
8Jiangsu Normal UniversityChina 46.338.2%61.2×8 -27.8%
9China Pharmaceutical UniversityChina 44.030.3%32.9×8 +179.3%
10Changzhou UniversityChina 43.330.2%30.2×9 -

Universities only. The score blends citation excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Axial and Atropisomeric Chirality Synthesis, country by country

Is Axial and Atropisomeric Chirality Synthesis research growing?

Output in 2022-2025 was 28% higher than in 2018-2021, peaking in 2009. The fastest-growing topics are Axial and Atropisomeric Chirality Synthesis.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Axial and Atropisomeric Chirality Synthesis as a percentage of every work published that year, 0.0059% in 2024.

still counting0.010%0.020%0.030%Axial and Atropisomeric Chirality Synthesis0.0056% in 202519801990200020102020

Fractional works of Axial and Atropisomeric Chirality Synthesis over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Axial and Atropisomeric Chirality Synthesis9.9% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

Discussion

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