BRCA gene mutations in cancer
BRCA gene mutations in cancer is a research topic within Genetics. Science Explorer counts 29k research works in it since 1950. 18.8% of them reached the world's top 10% most cited for their field and year.
This cluster of papers focuses on genetic research related to BRCA1 and BRCA2 mutations, and their association with breast and ovarian cancer risk. It covers topics such as genetic testing, precision medicine, genomic medicine, and the impact of mutations on cancer susceptibility.
- BRCA1
- BRCA2
- breast cancer
- ovarian cancer
- genetic testing
- cancer risk
- precision medicine
- genomic medicine
- mutation carriers
- cancer susceptibility
- Research works
- 29k fractional, since 1950
- In the world top 10%
- 5.4k per year above
- Top-10% rate
- 18.8% share of its works in the world top 10%
- Growth, 2013–17 → 2018–22
- +28% the tick is no change
Which countries lead BRCA gene mutations in cancer research?
By volume, the United States and the United Kingdom publish the most (2.1k and 363 works in 2022–2025).
By volume, 2022–2025
- 1 United States 2.1k works
- 2 United Kingdom 363 works
- 3 China 316 works
- 4 Italy 218 works
- 5 Canada 200 works
- 6 Australia 178 works
- 7 India 156 works
- 8 Japan 151 works
- 9 Germany 148 works
- 10 Netherlands 113 works
How concentrated that is
The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.
Shares of the rows listed above, not of the whole node.
Which institutions lead BRCA gene mutations in cancer research?
By volume in 2022–2025, University of North Carolina at Chapel Hill publishes the most BRCA gene mutations in cancer research, followed by The University of Texas MD Anderson Cancer Center and Memorial Sloan Kettering Cancer Center.
By volume, 2022–2025
- 1 University of North Carolina at Chapel HillUnited States 49 works
- 2 The University of Texas MD Anderson Cancer CenterUnited States 38 works
- 3 Memorial Sloan Kettering Cancer CenterUnited States 36 works
- 4 Harvard UniversityUnited States 35 works
- 5 University of MichiganUnited States 27 works
- 6 University of PennsylvaniaUnited States 27 works
- 7 Stanford UniversityUnited States 24 works
- 8 Cornell UniversityUnited States 23 works
- 9 University of WashingtonUnited States 23 works
- 10 Johns Hopkins UniversityUnited States 22 works
Who are the leading researchers in BRCA gene mutations in cancer?
The most-cited researchers publishing on BRCA gene mutations in cancer include Walter C. Willett, Gad Getz and Hermann Brenner.
- 1 Walter C. Willett United States 6.8k citations
- 2 Gad Getz United States 6.2k citations
- 3 Hermann Brenner Germany 5.8k citations
- 4 Andrew Kasarskis United States 4.8k citations
Ranked by citations received across their whole record, among researchers with at least three works on this topic.
Where is BRCA gene mutations in cancer research done?
The largest centres of BRCA gene mutations in cancer research in 2022–2025 are New York (United States), London (United Kingdom), Boston (United States) and Philadelphia (United States). Among places with at least 20 works in it, it is an unusually large share of all research in Bethesda.
Largest cities, 2022–2025
- 1 New York United States 151 works
- 2 London United Kingdom 133 works
- 3 Boston United States 99 works
- 4 Philadelphia United States 85 works
- 5 Toronto Canada 72 works
- 6 Houston United States 68 works
- 7 Melbourne Australia 68 works
- 8 Seoul South Korea 59 works
- 9 Chapel Hill United States 52 works
- 10 San Francisco United States 51 works
Where it is the local speciality
- BethesdaUS · 50.7 works7.7×
Location quotient: how much more of its research is in BRCA gene mutations in cancer than the world average.
Where is the best place to study BRCA gene mutations in cancer?
Among universities, judged by research, Harvard University, Queen Mary University of London and Weill Cornell Medicine score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.
One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.
| # | University | Score | Top 10% | Specialisation | Works | Growth |
|---|---|---|---|---|---|---|
| 1 | Harvard UniversityUnited States | 58.2 | 31.4% | 5.3× | 35 | +12.4% |
| 2 | Queen Mary University of LondonUnited Kingdom | 53.4 | 31.2% | 5.7× | 12 | +89.3% |
| 3 | Weill Cornell MedicineUnited States | 48.8 | 15.5% | 19.0× | 13 | — |
| 4 | University of CambridgeUnited Kingdom | 48.6 | 36.0% | 2.9× | 17 | +29.2% |
| 5 | University of California, San FranciscoUnited States | 46.7 | 24.0% | 6.0× | 20 | +40.6% |
| 6 | Karolinska InstitutetSweden | 46.3 | 37.9% | 3.7× | 9 | -6.4% |
| 7 | The University of MelbourneAustralia | 46.1 | 31.0% | 3.5× | 18 | +29.3% |
| 8 | University of PennsylvaniaUnited States | 44.6 | 20.7% | 5.5× | 27 | +26.7% |
| 9 | University of North Carolina at Chapel HillUnited States | 43.0 | 10.9% | 5.5× | 49 | +65.2% |
| 10 | Cornell UniversityUnited States | 42.5 | 18.8% | 4.3× | 23 | +89.6% |
Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.
Is BRCA gene mutations in cancer research growing?
Output in 2018–2022 was 28% higher than in 2013–2017, peaking in 2025. The fastest-growing topics are BRCA gene mutations in cancer.
The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.
Which topics inside it are moving
Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.