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Topic · Nephrology

Renal function and acid-base balance

Renal function and acid-base balance is a research topic within Nephrology. Science Explorer counts 28k research works in it since 1950. 10.1% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the diagnosis, management, and effects of metabolic acidosis, particularly in the context of chronic kidney disease. It explores the impact of bicarbonate therapy, dietary acid load, and renal function on acid-base balance, bone health, endothelin activity, and cardiovascular risk. The papers also discuss the potential benefits of nutritional interventions in addressing metabolic acidosis.

  • Metabolic Acidosis
  • Chronic Kidney Disease
  • Bicarbonate Therapy
  • Dietary Acid Load
  • Renal Function
  • Acid-Base Balance
  • Bone Health
  • Endothelin Activity
  • Cardiovascular Risk
  • Nutritional Intervention
Research works
28k
fractional, since 1950
In the world top 10%
2.9k
per year above
Top-10% rate
10.1%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+7%
the tick is no change
Largest producer
United States
37% of the 10 largest, 2022-now
Renal function and acid-base balance

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Renal function and acid-base balance research?

By volume, the United States and China publish the most (694 and 296 works in 2022-now).

By volume, 2022-now

  1. 1 United States 694 works
  2. 2 China 296 works
  3. 3 India 210 works
  4. 4 Germany 125 works
  5. 5 United Kingdom 114 works
  6. 6 Japan 97 works
  7. 7 Türkiye 95 works
  8. 8 Italy 90 works
  9. 9 Spain 79 works
  10. 10 Egypt 61 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 37.3%China: 15.9%India: 11.3%Germany: 6.7%6 others listed: 28.8%37%largest
United States694 · 37.3%China296 · 15.9%India210 · 11.3%Germany125 · 6.7%6 others listed536 · 28.8%

Shares of the rows listed above, not of the whole node.

Which institutions lead Renal function and acid-base balance research?

By volume in 2022-now, Harvard University publishes the most Renal function and acid-base balance research, followed by All India Institute of Medical Sciences and Mayo Clinic.

By volume, 2022-now

  1. 1 Harvard UniversityUnited States 16 works
  2. 2 All India Institute of Medical SciencesIndia 14 works
  3. 3 Mayo ClinicUnited States 13 works
  4. 4 Rutgers, The State University of New JerseyUnited States 12 works
  5. 5 Ain Shams UniversityEgypt 11 works
  6. 6 Sağlık Bilimleri ÜniversitesiTürkiye 10 works
  7. 7 Aarhus UniversityDenmark 10 works
  8. 8 University of California, DavisUnited States 9 works
  9. 9 Johns Hopkins UniversityUnited States 9 works
  10. 10 University of TorontoCanada 9 works

Who are the leading researchers in Renal function and acid-base balance?

The most-cited researchers publishing on Renal function and acid-base balance include George Davey Smith, Walter Churchill Willett and John J.V. McMurray.

  1. 1 George Davey Smith United Kingdom 435k citations
  2. 2 Walter Churchill Willett United States 411k citations
  3. 3 John J.V. McMurray United Kingdom 349k citations
  4. 4 Cyrus Cooper United Kingdom 342k citations
  5. 5 Emelia J. Benjamin United States 341k citations
  6. 6 Giuseppe Remuzzi Italy 328k citations
  7. 7 Gregory Y.H. Lip United Kingdom 311k citations
  8. 8 Salim Yusuf Canada 294k citations
  9. 9 Luigi Ferrucci United States 281k citations
  10. 10 Frank B. Hu United States 281k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Renal function and acid-base balance?

The most cited paper in Renal function and acid-base balance is "Intravenous Fluids and Acute Kidney Injury" (Xiaoqiang Ding, Zhen Cheng, Qi Qian, 2017), with 6,843 citations. Next come "Management of Chronic Kidney Disease Patients in the Intensive Care Unit: Mixing Acute and Chronic Illness" (5,015) and "Aortic Stiffness Is an Independent Predictor of All-Cause and Cardiovascular Mortality in Hypertensive Patients" (3,860).

Most cited papers
#PaperReleasedCitations
1 Intravenous Fluids and Acute Kidney Injury Xiaoqiang Ding, Zhen Cheng, Qi Qian · Blood Purification Open access 2017 6,843
2 Management of Chronic Kidney Disease Patients in the Intensive Care Unit: Mixing Acute and Chronic Illness Silvia De Rosa, Sara Samoni, Gianluca Villa et al. · Blood Purification Open access 2017 5,015
3 Aortic Stiffness Is an Independent Predictor of All-Cause and Cardiovascular Mortality in Hypertensive Patients Stéphane Laurent, Pierre Boutouyrie, Roland G Asmar et al. · Hypertension Open access May 2001 3,860
4 Clinical Practice Guideline for Screening and Management of High Blood Pressure in Children and Adolescents Joseph T. Flynn, David C. Kaelber, Carissa M. Baker‐Smith et al. · PEDIATRICS 22 Aug 2017 3,700
5 A RAPID AND PRECISE METHOD FOR THE DETERMINATION OF UREA Janet Fawcett, John E. Scott · Journal of Clinical Pathology Open access Mar 1960 2,803
All 101 most cited papers, with filters and sorting

Where is Renal function and acid-base balance research done?

The largest centres of Renal function and acid-base balance research in 2022-now are Beijing (China), London (United Kingdom), Istanbul (Türkiye) and New York (United States).

Largest cities, 2022-now

  1. 1 BeijingChina 35 works
  2. 2 LondonUnited Kingdom 32 works
  3. 3 IstanbulTürkiye 26 works
  4. 4 New YorkUnited States 24 works
  5. 5 TehranIran 23 works
  6. 6 New DelhiIndia 22 works
  7. 7 TokyoJapan 21 works
  8. 8 Mexico CityMexico 20 works
  9. 9 GuangzhouChina 20 works
  10. 10 ShanghaiChina 20 works
See Renal function and acid-base balance on the map

Where is the best place to study Renal function and acid-base balance?

Among universities, judged by research, Aarhus University, Harvard University and Johns Hopkins University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%30%mean 12.81%fractional works in this field (log) →share of work in the world top 10% →Aarhus UniversityJohns Hopkins Univer…Harvard UniversityAll India Institute …
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Aarhus UniversityDenmark 76.026.5%4.7×10 +77.3%
2Harvard UniversityUnited States 65.914.0%2.0×16 -24.2%
3Johns Hopkins UniversityUnited States 58.623.3%2.2×9 +88.5%
4All India Institute of Medical SciencesIndia 52.26.9%5.1×14 +25.1%
5Rutgers, The State University of New JerseyUnited States 47.52.6%6.0×12 +31.6%
6Sağlık Bilimleri ÜniversitesiTürkiye 44.76.6%7.5×10 +79.8%
7University College LondonUnited Kingdom 42.214.7%2.1×8 +4.1%
8University of California, DavisUnited States 40.45.4%4.5×9 +131.5%
9University of TorontoCanada 37.112.8%1.7×9 -12.5%
10Shanghai Jiao Tong UniversityChina 36.115.3%1.1×8 +259.8%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Renal function and acid-base balance, country by country

Is Renal function and acid-base balance research growing?

Output in 2022-2025 was 7% higher than in 2018-2021, peaking in 2024. The fastest-growing topics are Renal function and acid-base balance.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Renal function and acid-base balance as a percentage of every work published that year, 0.013% in 2024.

still counting0.050%0.10%Renal function and acid-base balance0.013% in 202519801990200020102020

Fractional works of Renal function and acid-base balance over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Renal function and acid-base balance10.6% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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