Science Explorer Interactive view Map

Synthesis and pharmacology of benzodiazepine derivatives

Synthesis and pharmacology of benzodiazepine derivatives is a research topic within Organic Chemistry. Science Explorer counts 5.8k research works in it since 1950. 7.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the chemistry, synthesis, and biological evaluation of pyrrolobenzodiazepines, a class of DNA-interactive agents with potent antitumour activity. The research covers topics such as asymmetric synthesis, cross-linking agents, cytotoxicity, and their application in natural product synthesis.

  • Pyrrolobenzodiazepines
  • Synthesis
  • DNA-Interactive Agents
  • Antitumour Activity
  • Asymmetric Synthesis
  • Isoindolinones
  • Cross-Linking Agents
  • Biological Evaluation
  • Cytotoxicity
  • Natural Products
Research works
5.8k
fractional, since 1950
In the world top 10%
404
per year above
Top-10% rate
7.0%
share of its works in the world top 10%
Growth, 2013–17 → 2018–22
-44%
the tick is no change

Which countries lead Synthesis and pharmacology of benzodiazepine derivatives research?

By volume, China and India publish the most (75 and 55 works in 2022–2025).

By volume, 2022–2025

  1. 1 China 75 works
  2. 2 India 55 works
  3. 3 United States 26 works
  4. 4 Russia 23 works
  5. 5 Japan 13 works
  6. 6 United Kingdom 10 works
  7. 7 Iran 9 works
  8. 8 Germany 8 works
  9. 9 France 6 works
  10. 10 Ukraine 6 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 32.5%India: 23.9%United States: 11.1%Russia: 10.2%6 others listed: 22.3%33%largest
China75 · 32.5%India55 · 23.9%United States26 · 11.1%Russia23 · 10.2%6 others listed51 · 22.3%

Shares of the rows listed above, not of the whole node.

Which institutions lead Synthesis and pharmacology of benzodiazepine derivatives research?

By volume in 2022–2025, Henan Normal University publishes the most Synthesis and pharmacology of benzodiazepine derivatives research, followed by Peoples' Friendship University of Russia and Academy of Scientific and Innovative Research.

Who are the leading researchers in Synthesis and pharmacology of benzodiazepine derivatives?

The most-cited researchers publishing on Synthesis and pharmacology of benzodiazepine derivatives include Alan R. Katritzky and Paul Knochel.

  1. 1 Alan R. Katritzky United States 2.3k citations
  2. 2 Paul Knochel Germany 1.5k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

Where is Synthesis and pharmacology of benzodiazepine derivatives research done?

The largest centres of Synthesis and pharmacology of benzodiazepine derivatives research in 2022–2025 are Beijing (China), Moscow (Russia), Shanghai (China) and Tehran (Iran).

Largest cities, 2022–2025

  1. 1 Beijing China 8 works
  2. 2 Moscow Russia 8 works
  3. 3 Shanghai China 6 works
  4. 4 Tehran Iran 5 works
  5. 5 London United Kingdom 5 works
  6. 6 Nanjing China 4 works
  7. 7 Kyiv Ukraine 4 works
  8. 8 New Delhi India 4 works
  9. 9 Chennai India 4 works
  10. 10 Kolkata India 4 works
See Synthesis and pharmacology of benzodiazepine derivatives on the map

Is Synthesis and pharmacology of benzodiazepine derivatives research growing?

Output in 2018–2022 was 44% lower than in 2013–2017, peaking in 2013.

19801990200020102020
grewheldshrank

The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.