Calpain Protease Function and Regulation
Calpain Protease Function and Regulation is a research topic within Cell Biology. Science Explorer counts 7.3k research works in it since 1950. 15.8% of them reached the world's top 10% most cited for their field and year.
This cluster of papers explores the role of calpain, a calcium-dependent protease, in regulating various cellular processes such as cell migration, neurodegeneration, apoptosis, and its involvement in diseases including diabetes, cancer, and cardiovascular remodeling. The papers also discuss the structure, activation, and inhibition of calpain as a potential therapeutic target.
- Calpain
- Cell Migration
- Neurodegeneration
- Proteolytic System
- Apoptosis
- Diabetes
- Cancer
- Mitochondria
- Inhibitors
- Cardiovascular Remodeling
- Research works
- 7.3k fractional, since 1950
- In the world top 10%
- 1.2k per year above
- Top-10% rate
- 15.8% share of its works in the world top 10%
- Growth, 2013–17 → 2018–22
- -14% the tick is no change
Which countries lead Calpain Protease Function and Regulation research?
By volume, China and the United States publish the most (193 and 97 works in 2022–2025).
By volume, 2022–2025
- 1 China 193 works
- 2 United States 97 works
- 3 India 41 works
- 4 Japan 24 works
- 5 Brazil 23 works
- 6 Germany 16 works
- 7 Türkiye 15 works
- 8 Canada 14 works
- 9 France 14 works
- 10 South Korea 13 works
How concentrated that is
The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.
Shares of the rows listed above, not of the whole node.
Which institutions lead Calpain Protease Function and Regulation research?
By volume in 2022–2025, National Institute of Biomedical Genomics publishes the most Calpain Protease Function and Regulation research, followed by University of Calcutta and Western University of Health Sciences.
By volume, 2022–2025
- 1 National Institute of Biomedical GenomicsIndia 4 works
- 2 University of CalcuttaIndia 4 works
- 3 Western University of Health SciencesUnited States 3 works
- 4 Queen's UniversityCanada 3 works
- 5 Soochow UniversityChina 3 works
- 6 Montreal Neurological Institute and HospitalCanada 2 works
- 7 Chongqing Medical UniversityChina 2 works
- 8 Northwest A&F UniversityChina 2 works
- 9 University of MichiganUnited States 2 works
- 10 Zhejiang UniversityChina 2 works
Who are the leading researchers in Calpain Protease Function and Regulation?
The most-cited researchers publishing on Calpain Protease Function and Regulation include Yasutomi Nishizuka.
- 1 Yasutomi Nishizuka Japan 3.1k citations
Ranked by citations received across their whole record, among researchers with at least three works on this topic.
Where is Calpain Protease Function and Regulation research done?
The largest centres of Calpain Protease Function and Regulation research in 2022–2025 are Beijing (China), Guangzhou (China), Shanghai (China) and Tokyo (Japan).
Is Calpain Protease Function and Regulation research growing?
Output in 2018–2022 was 14% lower than in 2013–2017, peaking in 2012.
The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.
Which topics inside it are moving
Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.