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Company · Gaithersburg · United States

Integrated BioTherapeutics (United States)

integratedbiotherapeutics.comROR OpenAlex
World rank, 2022-now
#22,362
of 22,385 · #28,853 all time
Rank in United States
#3,325
of 3,332
Research works
239
▲ 78% vs 2018-21
Citations
4.4k
18.4 per fractional work
Top-10% rate
7.7%
all institutions 10.0%
vs its own fields
0.93×
1.00× is exactly expected
Open access
44%
world 40%
International
17%
world 18%
Integrated BioTherapeutics (United States)

Which fields of science does Integrated BioTherapeutics (United States) work in?

In 2022-now, 51% of research at Integrated BioTherapeutics (United States) is in Health Sciences, 41% in Life Sciences. Its largest fields are Medicine (50%), Biochemistry, Genetics and Molecular Biology (22%), Immunology and Microbiology (18%). It does 2.7× the world's share of Life Sciences.

Health Sciences: 43 fractional works · 51.2% of its workMedicine: 42 fractional works · 50.4% of its workOncology: 17 fractional works · 20.4% of its workRadiology, Nuclear Medicine and Imaging: 9 fractional works · 11.1% of its workInfectious Diseases: 3 fractional works · 3.4% of its workPulmonary and Respiratory Medicine: 2 fractional works · 2.6% of its workPhysiology: 2 fractional works · 1.8% of its workGenetics: 1 fractional works · 1.5% of its workEpidemiology: 1 fractional works · 1.4% of its workPublic Health, Environmental and Occupational Health: 1 fractional works · 1.3% of its workPathology and Forensic Medicine: 1 fractional works · 1.2% of its workHematology: 1 fractional works · 1.0% of its workImmunology and Allergy: 1 fractional works · 0.9% of its workDermatology: 1 fractional works · 0.8% of its workComplementary and alternative medicine: 1 fractional works · 0.8% of its workCardiology and Cardiovascular Medicine: 1 fractional works · 0.7% of its workNeurology: 0 fractional works · 0.3% of its workSurgery: 0 fractional works · 0.3% of its workPediatrics, Perinatology and Child Health: 0 fractional works · 0.2% of its workSmaller subfields together: 1 fractional works · 0.7% of its workHealth Professions: 0 fractional works · 0.6% of its workEmergency Medical Services: 0 fractional works · 0.4% of its workSmaller subfields together: 0 fractional works · 0.2% of its workDentistry: 0 fractional works · 0.1% of its workNursing: 0 fractional works · 0.1% of its workVeterinary: 0 fractional works · 0.1% of its workLife Sciences: 35 fractional works · 41.5% of its workBiochemistry, Genetics and Molecular Biology: 18 fractional works · 21.6% of its workMolecular Biology: 9 fractional works · 10.8% of its workGenetics: 2 fractional works · 2.8% of its workBiotechnology: 2 fractional works · 2.5% of its workCancer Research: 2 fractional works · 2.2% of its workCell Biology: 1 fractional works · 1.4% of its workPhysiology: 1 fractional works · 1.0% of its workBiophysics: 0 fractional works · 0.4% of its workBiochemistry: 0 fractional works · 0.2% of its workClinical Biochemistry: 0 fractional works · 0.2% of its workImmunology and Microbiology: 15 fractional works · 17.7% of its workImmunology: 14 fractional works · 16.9% of its workMicrobiology: 1 fractional works · 0.7% of its workNeuroscience: 2 fractional works · 1.9% of its workNeurology: 2 fractional works · 1.8% of its workSmaller subfields together: 0 fractional works · 0.1% of its workPharmacology, Toxicology and Pharmaceutics: 0 fractional works · 0.2% of its workAgricultural and Biological Sciences: 0 fractional works · 0.1% of its workPhysical Sciences: 6 fractional works · 6.9% of its workEngineering: 4 fractional works · 4.9% of its workElectrical and Electronic Engineering: 2 fractional works · 2.6% of its workBiomedical Engineering: 2 fractional works · 1.9% of its workSmaller subfields together: 0 fractional works · 0.4% of its workComputer Science: 1 fractional works · 0.7% of its workComputational Theory and Mathematics: 0 fractional works · 0.6% of its workSmaller subfields together: 0 fractional works · 0.1% of its workMaterials Science: 0 fractional works · 0.5% of its workMaterials Chemistry: 0 fractional works · 0.2% of its workSmaller subfields together: 0 fractional works · 0.3% of its workChemistry: 0 fractional works · 0.3% of its workEnergy: 0 fractional works · 0.2% of its workMathematics: 0 fractional works · 0.2% of its workEnvironmental Science: 0 fractional works · 0.1% of its workSocial Sciences: 0 fractional works · 0.3% of its workEconomics, Econometrics and Finance: 0 fractional works · 0.2% of its workArts and Humanities: 0 fractional works · 0.1% of its workPsychology: 0 fractional works · 0.1% of its workALL ITS WORKIntegratedBioTherapeutics…84fractional works, 2022-now
Life Sciences41%Physical Sciences7%Health Sciences51%Social Sciences0%

Each ring splits the one inside it: the four domains of science, their fields, their subfields. Size is fractional works in 2022-now. Every slice is a page; the interactive view zooms down to single topics and colours each by how much more of it this institution does than the world.

Its 4 domains and 20 fields, with their numbers
    1. Medicine4250.4%
    2. Health Professions00.6%
    3. Dentistry00.1%
    4. Nursing00.1%
    5. Veterinary00.1%
    1. Biochemistry, Genetics and Molecular Biology1821.6%
    2. Immunology and Microbiology1517.7%
    3. Neuroscience21.9%
    4. Pharmacology, Toxicology and Pharmaceutics00.2%
    5. Agricultural and Biological Sciences00.1%
    1. Engineering44.9%
    2. Computer Science10.7%
    3. Materials Science00.5%
    4. Chemistry00.3%
    5. Energy00.2%
    6. Mathematics00.2%
    7. Environmental Science00.1%
    1. Economics, Econometrics and Finance00.2%
    2. Arts and Humanities00.1%
    3. Psychology00.1%
All of science, and how each field's share has moved since 1950: the Science domain explorer

Field profile

Location quotient across every field it publishes in: outside the ring is more than an institution of this size would be expected to publish, inside it is less.

Agricultural and Biological Sciences: 0.01× its world share, 0 worksAgricultural and Bio…Biochemistry, Genetics and Molecular Biology: 4.06× its world share, 18 worksBiochemistry, Geneti…Immunology and Microbiology: 17.57× its world share, 15 worksImmunology and Micro…Neuroscience: 1.16× its world share, 2 worksNeurosciencePharmacology, Toxicology and Pharmaceutics: 0.56× its world share, 0 worksPharmacology, Toxico…Chemistry: 0.20× its world share, 0 worksChemistryComputer Science: 0.09× its world share, 1 worksComputer ScienceEnergy: 0.22× its world share, 0 worksEnergyEngineering: 0.33× its world share, 4 worksEngineeringEnvironmental Science: 0.03× its world share, 0 worksEnvironmental ScienceMaterials Science: 0.14× its world share, 0 worksMaterials ScienceMathematics: 0.17× its world share, 0 worksMathematicsDentistry: 0.27× its world share, 0 worksDentistryHealth Professions: 0.22× its world share, 0 worksHealth ProfessionsMedicine: 2.62× its world share, 42 worksMedicineNursing: 0.20× its world share, 0 worksNursingVeterinary: 0.48× its world share, 0 worksVeterinaryArts and Humanities: 0.02× its world share, 0 worksArts and HumanitiesEconomics, Econometrics and Finance: 0.09× its world share, 0 worksEconomics, Econometr…Psychology: 0.02× its world share, 0 worksPsychology1×world share
more than its size predictsabout as predictedless

Rings at 0.5×, 1× and 2×. Widest outward: Immunology and Microbiology, 17.6×. Every wedge is a field page.

All 20 fields, with their numbers
  1. Immunology and Microbiology17.57×15 works
  2. Biochemistry, Genetics and Molecular Biology4.06×18 works
  3. Medicine2.62×42 works
  4. Neuroscience1.16×2 works
  5. Pharmacology, Toxicology and Pharmaceutics0.56×0 works
  6. Veterinary0.48×0 works
  7. Engineering0.33×4 works
  8. Dentistry0.27×0 works
  9. Energy0.22×0 works
  10. Health Professions0.22×0 works
  11. Chemistry0.20×0 works
  12. Nursing0.20×0 works
  13. Mathematics0.17×0 works
  14. Materials Science0.14×0 works
  15. Computer Science0.09×1 works
  16. Economics, Econometrics and Finance0.09×0 works
  17. Environmental Science0.03×0 works
  18. Arts and Humanities0.02×0 works
  19. Psychology0.02×0 works
  20. Agricultural and Biological Sciences0.01×0 works

Who are the top researchers at Integrated BioTherapeutics (United States)?

Ranked on the quality score, M. Javad Aman, Sergey Shulenin and Frederick W. Holtsberg lead among researchers whose main affiliation is Integrated BioTherapeutics (United States).

  1. 1 M. Javad Aman United States · #190,155 worldwide 8.9k citations · 163 works
  2. 2 Sergey Shulenin United States · #442,537 worldwide 3.4k citations · 52 works
  3. 3 Frederick W. Holtsberg United States · #476,693 worldwide 4.4k citations · 80 works
  4. 4 Sven G. Enterlein United States · #552,519 worldwide 1.8k citations · 27 works
  5. 5 Katie A. Howell United States · #673,723 worldwide 866 citations · 21 works
  6. 6 Hong Vu United States · #707,509 worldwide 1.8k citations · 46 works
  7. 7 Alexander Kamb United States · #721,819 worldwide 17k citations · 163 works
  8. 8 Eric J. Stavale United States · #870,224 worldwide 1.2k citations · 22 works
  9. 9 Breanna DiAndreth United States · #950,150 worldwide 831 citations · 29 works
  10. 10 Rajan P. Adhikari United States · #1,238,715 worldwide 1.6k citations · 37 works
All ranked researchers at Integrated BioTherapeutics (United States)

What are the most cited papers from Integrated BioTherapeutics (United States)?

The most cited paper from Integrated BioTherapeutics (United States) is "Production of α-1,3-Galactosyltransferase Knockout Pigs by Nuclear Transfer Cloning" (Liangxue Lai, Donna Kolber‐Simonds, Kwang‐Wook Park et al., 2002), with 1,344 citations. Next come "Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth" (552) and "Seasonal Pulses of Marburg Virus Circulation in Juvenile Rousettus aegyptiacus Bats Coincide with Periods of Increased Risk of Human Infection" (472).

Most cited papers
#PaperReleasedCitations
1 Production of α-1,3-Galactosyltransferase Knockout Pigs by Nuclear Transfer Cloning Liangxue Lai, Donna Kolber‐Simonds, Kwang‐Wook Park et al. · Science 8 Feb 2002 1,344
2 Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth Shira L. Cramer, Achinto Saha, Jinyun Liu et al. · Nature Medicine Open access 21 Nov 2016 552
3 Seasonal Pulses of Marburg Virus Circulation in Juvenile Rousettus aegyptiacus Bats Coincide with Periods of Increased Risk of Human Infection Brian R. Amman et al. · PLoS Pathogens Open access 4 Oct 2012 472
4 PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance Vivek Verma et al. · Nature Immunology Open access 29 Jul 2019 341
5 Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein(a). MacRae F. Linton, Robert V. Farese, Giulia Chiesa et al. · Journal of Clinical Investigation Open access Dec 1993 247
All 61 most cited papers, with filters and sorting

Which keywords describe research at Integrated BioTherapeutics (United States)?

By fractional works in 2022-now, weighted toward what it does more of than the world: Cancer Immunotherapy, Immunotherapy, Tumor Regression, Lymphoma, Leukemia, Glycosylation, CAR T Cells and Chimeric Antigen Receptor.

▲ more of its work than of the world's◆ about the world's share▼ less than the world's

Size is fractional works in 2022-now in the topics tagged with each word; colour is the word's share of this institution's work against its share of the world's. The 40 words are chosen for being large and distinctive. Each links to the topic it comes from most.

All 40 words, with their numbers
  1. Cancer Immunotherapy14▲ 108×3 topics
  2. Immunotherapy13▲ 22×10 topics
  3. Tumor Regression11▲ 113×2 topics
  4. Leukemia9▲ 133×2 topics
  5. Lymphoma9▲ 70×3 topics
  6. CAR T Cells9▲ 147×1 topic
  7. Chimeric Antigen Receptor9▲ 147×1 topic
  8. Glycosylation9▲ 98×3 topics
  9. Monoclonal Antibodies8▲ 107×2 topics
  10. Fc Receptors8▲ 163×1 topic
  11. Therapeutic Antibodies8▲ 128×1 topic
  12. Innate Immunity7▲ 25×6 topics
  13. Tumor Microenvironment6▲ 16×8 topics
  14. Immunity6▲ 17×5 topics
  15. Epidemiology6▲ 1.63×23 topics
  16. Antigen Presentation5▲ 70×2 topics
  17. Gene Therapy5▲ 31×4 topics
  18. Dendritic Cells5▲ 65×2 topics
  19. Tumor Antigen5▲ 94×1 topic
  20. Vaccine Adjuvants5▲ 94×1 topic
  21. Targeted Therapy4▲ 22×5 topics
  22. NK Cell Recognition4▲ 73×1 topic
  23. Natural Killer Cells4▲ 73×1 topic
  24. Immune Checkpoint Blockade3▲ 31×1 topic
  25. Monoclonal Antibody3▲ 65×2 topics
  26. PD-1 and PD-L13▲ 31×1 topic
  27. Chemotherapy3▲ 4.9×8 topics
  28. Clinical Trials3▲ 4.8×7 topics
  29. Tumor Targeting3▲ 17×3 topics
  30. AAV2▲ 64×1 topic
  31. Cancer Therapy2▲ 4.4×8 topics
  32. PET Imaging2▲ 15×3 topics
  33. TGF-ß2▲ 15×3 topics
  34. Viral Vectors2▲ 64×1 topic
  35. Breast Cancer2▲ 8.9×4 topics
  36. HER22▲ 67×1 topic
  37. Trastuzumab2▲ 43×1 topic
  38. CD4+CD25+2▲ 60×1 topic
  39. Foxp32▲ 60×1 topic
  40. Arginine Deprivation2▲ 50×1 topic

Which research topics does Integrated BioTherapeutics (United States) publish most on?

By volume in 2022-now: CAR-T cell therapy research, Monoclonal and Polyclonal Antibodies Research, Immunotherapy and Immune Responses and Immune Cell Function and Interaction.

CAR-T cell therapy resea…9CAR-T cell therapy research: 9 fractional worksMonoclonal and Polyclonal Antibodies Research: 8 fractional worksImmunotherapy and Immune Responses: 5 fractional worksImmune Cell Function and Interaction: 4 fractional worksCancer Immunotherapy and Biomarkers: 3 fractional worksVirus-based gene therapy…2Virus-based gene therapy research: 2 fractional worksHER2/EGFR in Cancer Research: 2 fractional worksT-cell and B-cell Immunology: 2 fractional worksCancer Research and Treatments: 2 fractional worksCancer Genomics and Diagnostics: 1 fractional works
OncologyRadiology, Nuclear Medicine and ImagingImmunologyGenetics2 others

Area is fractional works; colour is the subfield each topic belongs to.

  1. 1 CAR-T cell therapy research Oncology 9 works
  2. 2 Monoclonal and Polyclonal Antibodies Research Radiology, Nuclear Medicine and Imaging 8 works
  3. 3 Immunotherapy and Immune Responses Immunology 5 works
  4. 4 Immune Cell Function and Interaction Immunology 4 works
  5. 5 Cancer Immunotherapy and Biomarkers Oncology 3 works
  6. 6 Virus-based gene therapy research Genetics 2 works
  7. 7 HER2/EGFR in Cancer Research Oncology 2 works
  8. 8 T-cell and B-cell Immunology Immunology 2 works
  9. 9 Cancer Research and Treatments Biotechnology 2 works
  10. 10 Cancer Genomics and Diagnostics Cancer Research 1 works

How open and international is its research?

Against the world's own shares: the tick on each track. Both are shares of its output, so they sit on one scale and can be read against each other as well as against the world.

openly available43.8%not open56.2%

World: 40% of research is openly available.

with international co-authors16.7%domestic only83.3%

World: 18% is written across borders.

How has Integrated BioTherapeutics (United States)'s research output changed?

Output in 2022-2025 was 78% higher than in 2018-2021.

still counting1990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Integrated BioTherapeutics (United States) as a percentage of every work published that year, 0.00029% in 2024.

still counting0.0010%0.0020%Integrated BioTherapeutics (United States)0.00044% in 202519801990200020102020

Fractional works of Integrated BioTherapeutics (United States) over all fractional works that year. How the balance of science has shifted.

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