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Company · Leiden · Netherlands

ISA Pharmaceuticals (Netherlands)

isa-pharma.comROR OpenAlex
Research works
38
▼ 17% vs 2018-21
Citations
3.9k
101.6 per fractional work
Top-10% rate
10.3%
all institutions 10.0%
Open access
56%
world 40%
International
26%
world 18%
ISA Pharmaceuticals (Netherlands)

Not ranked overall: ISA Pharmaceuticals (Netherlands) is under the volume floor below which an excellence rate is noise. Not ranked is not the same as ranked last.

Which fields of science does ISA Pharmaceuticals (Netherlands) work in?

In all years, 53% of research at ISA Pharmaceuticals (Netherlands) is in Life Sciences, 46% in Health Sciences. Its largest fields are Medicine (44%), Immunology and Microbiology (40%), Biochemistry, Genetics and Molecular Biology (10%). It does 2.7× the world's share of Life Sciences.

Life Sciences: 20 fractional works · 53.0% of its workImmunology and Microbiology: 15 fractional works · 40.0% of its workImmunology: 15 fractional works · 38.8% of its workMicrobiology: 0 fractional works · 0.7% of its workVirology: 0 fractional works · 0.4% of its workBiochemistry, Genetics and Molecular Biology: 4 fractional works · 10.5% of its workMolecular Biology: 3 fractional works · 8.2% of its workGenetics: 1 fractional works · 1.4% of its workCell Biology: 0 fractional works · 0.6% of its workBiotechnology: 0 fractional works · 0.3% of its workNeuroscience: 1 fractional works · 1.5% of its workDevelopmental Neuroscience: 0 fractional works · 0.7% of its workNeurology: 0 fractional works · 0.3% of its workSensory Systems: 0 fractional works · 0.3% of its workCellular and Molecular Neuroscience: 0 fractional works · 0.3% of its workAgricultural and Biological Sciences: 0 fractional works · 0.6% of its workFood Science: 0 fractional works · 0.6% of its workPharmacology, Toxicology and Pharmaceutics: 0 fractional works · 0.5% of its workPharmaceutical Science: 0 fractional works · 0.5% of its workHealth Sciences: 17 fractional works · 45.5% of its workMedicine: 17 fractional works · 44.2% of its workOncology: 8 fractional works · 20.7% of its workEpidemiology: 4 fractional works · 10.3% of its workRadiology, Nuclear Medicine and Imaging: 1 fractional works · 2.1% of its workSurgery: 1 fractional works · 1.5% of its workHepatology: 1 fractional works · 1.5% of its workPediatrics, Perinatology and Child Health: 0 fractional works · 1.2% of its workPulmonary and Respiratory Medicine: 0 fractional works · 1.0% of its workEndocrinology, Diabetes and Metabolism: 0 fractional works · 1.0% of its workPublic Health, Environmental and Occupational Health: 0 fractional works · 0.9% of its workInfectious Diseases: 0 fractional works · 0.7% of its workCritical Care and Intensive Care Medicine: 0 fractional works · 0.7% of its workOphthalmology: 0 fractional works · 0.6% of its workObstetrics and Gynecology: 0 fractional works · 0.5% of its workDermatology: 0 fractional works · 0.3% of its workEmergency Medicine: 0 fractional works · 0.3% of its workOtorhinolaryngology: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.7% of its workHealth Professions: 0 fractional works · 0.7% of its workSpeech and Hearing: 0 fractional works · 0.4% of its workComplementary and Manual Therapy: 0 fractional works · 0.3% of its workVeterinary: 0 fractional works · 0.4% of its workSmall Animals: 0 fractional works · 0.4% of its workNursing: 0 fractional works · 0.1% of its workPhysical Sciences: 0 fractional works · 1.1% of its workChemistry: 0 fractional works · 0.6% of its workSpectroscopy: 0 fractional works · 0.5% of its workSmaller subfields together: 0 fractional works · 0.1% of its workEnvironmental Science: 0 fractional works · 0.2% of its workEcology: 0 fractional works · 0.2% of its workComputer Science: 0 fractional works · 0.2% of its workMathematics: 0 fractional works · 0.1% of its workEngineering: 0 fractional works · 0.0% of its workSocial Sciences: 0 fractional works · 0.4% of its workEconomics, Econometrics and Finance: 0 fractional works · 0.3% of its workEconomics and Econometrics: 0 fractional works · 0.3% of its workSocial Sciences: 0 fractional works · 0.0% of its workALL ITS WORKISAPharmaceuticals…38fractional works, all years
Life Sciences53%Physical Sciences1%Health Sciences46%Social Sciences0%

Each ring splits the one inside it: the four domains of science, their fields, their subfields. Size is fractional works in all years. Every slice is a page; the interactive view zooms down to single topics and colours each by how much more of it this institution does than the world.

Its 4 domains and 16 fields, with their numbers
    1. Immunology and Microbiology1540.0%
    2. Biochemistry, Genetics and Molecular Biology410.5%
    3. Neuroscience11.5%
    4. Agricultural and Biological Sciences00.6%
    5. Pharmacology, Toxicology and Pharmaceutics00.5%
    1. Medicine1744.2%
    2. Health Professions00.7%
    3. Veterinary00.4%
    4. Nursing00.1%
    1. Chemistry00.6%
    2. Environmental Science00.2%
    3. Computer Science00.2%
    4. Mathematics00.1%
    5. Engineering00.0%
    1. Economics, Econometrics and Finance00.3%
    2. Social Sciences00.0%
All of science, and how each field's share has moved since 1950: the Science domain explorer

Field profile

Location quotient across every field it publishes in: outside the ring is more than an institution of this size would be expected to publish, inside it is less.

Agricultural and Biological Sciences: 0.10× its world share, 0 worksAgricultural and Bio…Biochemistry, Genetics and Molecular Biology: 1.74× its world share, 0 worksBiochemistry, Geneti…Immunology and Microbiology: 33.97× its world share, 2 worksImmunology and Micro…Neuroscience: 2.73× its world share, 0 worksNeurosciencePharmacology, Toxicology and Pharmaceutics: 1.40× its world share, 0 worksPharmacology, Toxico…Chemistry: 0.31× its world share, 0 worksChemistryEngineering: 0.02× its world share, 0 worksEngineeringEnvironmental Science: 0.30× its world share, 0 worksEnvironmental ScienceMedicine: 2.52× its world share, 3 worksMedicineEconomics, Econometrics and Finance: 0.12× its world share, 0 worksEconomics, Econometr…Social Sciences: 0.02× its world share, 0 worksSocial Sciences1×world share
more than its size predictsabout as predictedless

Rings at 0.5×, 1× and 2×. Widest outward: Immunology and Microbiology, 34.0×. Every wedge is a field page.

All 11 fields, with their numbers
  1. Immunology and Microbiology33.97×2 works
  2. Neuroscience2.73×0 works
  3. Medicine2.52×3 works
  4. Biochemistry, Genetics and Molecular Biology1.74×0 works
  5. Pharmacology, Toxicology and Pharmaceutics1.40×0 works
  6. Chemistry0.31×0 works
  7. Environmental Science0.30×0 works
  8. Economics, Econometrics and Finance0.12×0 works
  9. Agricultural and Biological Sciences0.10×0 works
  10. Engineering0.02×0 works
  11. Social Sciences0.02×0 works

Who are the top researchers at ISA Pharmaceuticals (Netherlands)?

Ranked on the quality score, Willem-Jan Krebber lead among researchers whose main affiliation is ISA Pharmaceuticals (Netherlands).

  1. 1 Willem-Jan Krebber Netherlands · #1,577,678 worldwide 2.8k citations · 15 works
All ranked researchers at ISA Pharmaceuticals (Netherlands)

What are the most cited papers from ISA Pharmaceuticals (Netherlands)?

The most cited paper from ISA Pharmaceuticals (Netherlands) is "Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens" (Matthew M. Gubin et al., 2014), with 2,015 citations. Next come "CD4+ T cell help in cancer immunology and immunotherapy" (1,685) and "Therapeutic cancer vaccines" (1,589).

Most cited papers
#PaperReleasedCitations
1 Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens Matthew M. Gubin et al. · Nature Open access 25 Nov 2014 2,015
2 CD4+ T cell help in cancer immunology and immunotherapy Jannie G. Borst, Tomasz Ahrends, Nikolina Bąbała et al. · Nature reviews. Immunology Review 29 Jul 2018 1,685
3 Therapeutic cancer vaccines Mansi Saxena, Sjoerd H. van der Burg, Cornelis J.M. Melief et al. · Nature reviews. Cancer Review 27 Apr 2021 1,589
4 Therapeutic cancer vaccines Cornelis J.M. Melief, Thorbald van Hall, Ramon Arens et al. · Journal of Clinical Investigation Open access 27 Jul 2015 1,170
5 Vaccination against HPV-16 Oncoproteins for Vulvar Intraepithelial Neoplasia Gemma G. Kenter, Marij J.P. Welters, A. Rob P.M. Valentijn et al. · New England Journal of Medicine Open access 4 Nov 2009 1,100
All 60 most cited papers, with filters and sorting

Which keywords describe research at ISA Pharmaceuticals (Netherlands)?

By fractional works in all years, weighted toward what it does more of than the world: Antigen Presentation, Cancer Immunotherapy, Immunity, Dendritic Cells, Innate Immunity, Tumor Antigen, Vaccine Adjuvants and Tumor Microenvironment.

▲ more of its work than of the world's◆ about the world's share▼ less than the world's

Size is fractional works in all years in the topics tagged with each word; colour is the word's share of this institution's work against its share of the world's. The 37 words are chosen for being large and distinctive. Each links to the topic it comes from most.

All 37 words, with their numbers
  1. Antigen Presentation12▲ 303×2 topics
  2. Cancer Immunotherapy11▲ 197×2 topics
  3. Immunity10▲ 81×6 topics
  4. Dendritic Cells9▲ 212×2 topics
  5. Innate Immunity9▲ 69×2 topics
  6. Tumor Antigen9▲ 293×1 topic
  7. Vaccine Adjuvants9▲ 293×1 topic
  8. Tumor Microenvironment5▲ 40×4 topics
  9. Immune Checkpoint Blockade5▲ 233×1 topic
  10. PD-1 and PD-L15▲ 233×1 topic
  11. Epidemiology4▲ 2.8×13 topics
  12. Global Burden3▲ 15×2 topics
  13. Cancer Incidence3▲ 54×2 topics
  14. Human Papillomavirus3▲ 59×3 topics
  15. Inflammation3▲ 3.1×8 topics
  16. Viral Oncoproteins3▲ 101×2 topics
  17. Immunotherapy3▲ 11×8 topics
  18. Cervical Cancer3▲ 69×2 topics
  19. Epitope Prediction2▲ 344×1 topic
  20. Peptide-MHC Binding2▲ 344×1 topic
  21. Cytology Screening2▲ 125×1 topic
  22. HPV Vaccination2▲ 125×1 topic
  23. Leukemia2▲ 78×2 topics
  24. Lymphoma2▲ 34×2 topics
  25. Immune Response2▲ 7.6×10 topics
  26. NK Cell Recognition2▲ 47×1 topic
  27. Natural Killer Cells2▲ 47×1 topic
  28. Cancer2▲ 3.0×11 topics
  29. Tumor Regression2▲ 46×2 topics
  30. CAR T Cells1▲ 87×1 topic
  31. Chimeric Antigen Receptor1▲ 87×1 topic
  32. Pattern Recognition Receptors1▲ 23×1 topic
  33. Toll-like Receptors1▲ 20×1 topic
  34. Immunosuppression1▲ 26×3 topics
  35. Autoimmunity1▲ 14×2 topics
  36. Metabolism1▲ 4.4×2 topics
  37. Antiviral Therapy1▲ 18×3 topics

Which research topics does ISA Pharmaceuticals (Netherlands) publish most on?

By volume in 2022-now: Immunotherapy and Immune Responses, Cancer Immunotherapy and Biomarkers, vaccines and immunoinformatics approaches and Cervical Cancer and HPV Research.

Immunotherapy and Immune…1Immunotherapy and Immune Responses: 1 fractional worksCancer Immunotherapy and…1Cancer Immunotherapy and Biomarkers: 1 fractional worksvaccines and immunoinfor…0vaccines and immunoinformatics approaches: 0 fractional worksCervical Cancer and HPV Research: 0 fractional worksT-cell and Retrovirus Studies: 0 fractional worksImmune Cell Function and Interaction: 0 fractional worksIntensive Care Unit Cognitive Disorders: 0 fractional worksAnesthesia and Neurotoxicity Research: 0 fractional worksViral-associated cancers and disorders: 0 fractional worksHepatitis B Virus Studies: 0 fractional works
ImmunologyOncologyMolecular BiologyEpidemiology2 others

Area is fractional works; colour is the subfield each topic belongs to.

  1. 1 Immunotherapy and Immune Responses Immunology 1 works
  2. 2 Cancer Immunotherapy and Biomarkers Oncology 1 works
  3. 3 vaccines and immunoinformatics approaches Molecular Biology 0 works
  4. 4 Cervical Cancer and HPV Research Epidemiology 0 works
  5. 5 T-cell and Retrovirus Studies Immunology 0 works
  6. 6 Immune Cell Function and Interaction Immunology 0 works
  7. 7 Intensive Care Unit Cognitive Disorders Critical Care and Intensive Care Medicine 0 works
  8. 8 Anesthesia and Neurotoxicity Research Developmental Neuroscience 0 works
  9. 9 Viral-associated cancers and disorders Oncology 0 works
  10. 10 Hepatitis B Virus Studies Epidemiology 0 works

How open and international is its research?

Against the world's own shares: the tick on each track. Both are shares of its output, so they sit on one scale and can be read against each other as well as against the world.

openly available56.4%not open43.6%

World: 40% of research is openly available.

with international co-authors25.6%domestic only74.4%

World: 18% is written across borders.

How has ISA Pharmaceuticals (Netherlands)'s research output changed?

Output in 2022-2025 was 17% lower than in 2018-2021.

still counting200020052010201520202025
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is ISA Pharmaceuticals (Netherlands) as a percentage of every work published that year, 0.0000034% in 2024.

still counting0.000050%0.00010%0.00015%ISA Pharmaceuticals (Netherlands)0.00000068% in 2025200020102020

Fractional works of ISA Pharmaceuticals (Netherlands) over all fractional works that year. How the balance of science has shifted.

Other research institutions in Leiden

All research institutions in Leiden

Research measures only: rankings here say nothing about teaching, admissions or student experience. Comparable institutions and collaboration partners have tabs of their own, above.

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