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Topic · Biochemistry

Antioxidant Activity and Oxidative Stress

Antioxidant Activity and Oxidative Stress is a research topic within Biochemistry. Science Explorer counts 44k research works in it since 1950. 10.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the role of oxidative stress, antioxidants, lipid peroxidation, and carotenoids in various health conditions such as atherosclerosis, cardiovascular disease, cancer prevention, and eye health. It investigates the impact of reactive oxygen species, biomarkers of oxidative damage, and the potential use of vitamin E in mitigating oxidative stress-related diseases.

  • Oxidative Stress
  • Antioxidants
  • Lipid Peroxidation
  • Carotenoids
  • Vitamin E
  • Atherosclerosis
  • Reactive Oxygen Species
  • Biomarkers
  • Inflammation
  • Cancer Prevention
Research works
44k
fractional, since 1950
In the world top 10%
4.3k
per year above
Top-10% rate
10.0%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-2%
the tick is no change
Largest producer
China
36% of the 10 largest, 2022-now
Antioxidant Activity and Oxidative Stress

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Antioxidant Activity and Oxidative Stress research?

By volume, China and the United States publish the most (1.4k and 658 works in 2022-now).

By volume, 2022-now

  1. 1 China 1.4k works
  2. 2 United States 658 works
  3. 3 India 376 works
  4. 4 Brazil 313 works
  5. 5 Italy 202 works
  6. 6 Spain 186 works
  7. 7 Iran 180 works
  8. 8 Türkiye 179 works
  9. 9 South Korea 173 works
  10. 10 Japan 173 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 36.3%United States: 17.2%India: 9.8%Brazil: 8.2%6 others listed: 28.5%36%largest
China1,391 · 36.3%United States658 · 17.2%India376 · 9.8%Brazil313 · 8.2%6 others listed1,094 · 28.5%

Shares of the rows listed above, not of the whole node.

Which institutions lead Antioxidant Activity and Oxidative Stress research?

By volume in 2022-now, Chinese Academy of Agricultural Sciences publishes the most Antioxidant Activity and Oxidative Stress research, followed by Russian Academy of Sciences and Ministry of Agriculture and Rural Affairs.

By volume, 2022-now

  1. 1 Chinese Academy of Agricultural SciencesChina 67 works
  2. 2 Russian Academy of SciencesRussia 42 works
  3. 3 Ministry of Agriculture and Rural AffairsChina 30 works
  4. 4 Chinese Academy of SciencesChina 30 works
  5. 5 Consejo Superior de Investigaciones CientíficasSpain 26 works
  6. 6 Islamic Azad University, TehranIran 24 works
  7. 7 Zhejiang UniversityChina 23 works
  8. 8 United States Department of AgricultureUnited States 21 works
  9. 9 Centre National de la Recherche ScientifiqueFrance 21 works
  10. 10 Universidade de São PauloBrazil 20 works

Who are the leading researchers in Antioxidant Activity and Oxidative Stress?

The most-cited researchers publishing on Antioxidant Activity and Oxidative Stress include George Davey Smith, Ali H. Mokdad and Walter Churchill Willett.

  1. 1 George Davey Smith United Kingdom 435k citations
  2. 2 Ali H. Mokdad United States 429k citations
  3. 3 Walter Churchill Willett United States 411k citations
  4. 4 Guido Kroemer France 386k citations
  5. 5 Zulfiqar Ahmed Bhutta Pakistan 371k citations
  6. 6 Hermann Brenner Germany 343k citations
  7. 7 Cyrus Cooper United Kingdom 342k citations
  8. 8 Emelia J. Benjamin United States 341k citations
  9. 9 Jun Wang China 340k citations
  10. 10 Mika Kivimäki United Kingdom 318k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Antioxidant Activity and Oxidative Stress?

The most cited paper in Antioxidant Activity and Oxidative Stress is "Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues" (Haider Raza, Annie John, Abderrahim Nemmar, 2013), with 47,289 citations. Next come "Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction" (29,425) and "Antioxidant activity applying an improved ABTS radical cation decolorization assay" (26,207).

Most cited papers
#PaperReleasedCitations
1 Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues Haider Raza, Annie John, Abderrahim Nemmar · Cellular Physiology and Biochemistry Open access 2013 47,289
2 Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction Hiroshi Ohkawa, Nobuko Ohishi, Kunio Yagi · Analytical Biochemistry Jun 1979 29,425
3 Antioxidant activity applying an improved ABTS radical cation decolorization assay Roberta Re, Nicoletta Pellegrini, Anna R. Proteggente et al. · Free Radical Biology and Medicine May 1999 26,207
4 Use of a free radical method to evaluate antioxidant activity Wendy Brand-Williams, Marie‐Elisabeth Cuvelier, Claudette Berset · LWT Open access 1995 25,846
5 Free Radicals in the Physiological Control of Cell Function Wulf Dröge · Physiological Reviews Review 2002 9,887
All 100 most cited papers, with filters and sorting

Where is Antioxidant Activity and Oxidative Stress research done?

The largest centres of Antioxidant Activity and Oxidative Stress research in 2022-now are Beijing (China), Guangzhou (China), Seoul (South Korea) and Nanjing (China).

Largest cities, 2022-now

  1. 1 BeijingChina 196 works
  2. 2 GuangzhouChina 84 works
  3. 3 SeoulSouth Korea 68 works
  4. 4 NanjingChina 66 works
  5. 5 TehranIran 65 works
  6. 6 WuhanChina 57 works
  7. 7 ShanghaiChina 54 works
  8. 8 HangzhouChina 52 works
  9. 9 MoscowRussia 52 works
  10. 10 São PauloBrazil 50 works
See Antioxidant Activity and Oxidative Stress on the map

Where is the best place to study Antioxidant Activity and Oxidative Stress?

Among universities, judged by research, Zhejiang University, Medical University of Lodz and Northeast Agricultural University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 19.68%fractional works in this field (log) →share of work in the world top 10% →Northeast Agricultur…Medical University o…Harvard UniversityZhejiang University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Zhejiang UniversityChina 66.015.6%1.7×23 +23.4%
2Medical University of LodzPoland 65.634.0%13.4×11 +63.2%
3Northeast Agricultural UniversityChina 64.236.3%7.3×10 +20.6%
4Harvard UniversityUnited States 61.915.7%1.2×20 -25.6%
5Nanchang UniversityChina 58.212.3%4.7×18 +12.7%
6Huazhong Agricultural UniversityChina 58.118.5%8.8×15 +8.4%
7Nanjing Agricultural UniversityChina 56.514.4%8.1×16 +45.8%
8China Agricultural UniversityChina 51.79.9%6.0×17 +27.1%
9Huazhong University of Science and TechnologyChina 51.221.4%1.4×13 +92.7%
10Ocean University of ChinaChina 50.718.7%4.0×10 +29.0%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Antioxidant Activity and Oxidative Stress, country by country

Is Antioxidant Activity and Oxidative Stress research growing?

Output in 2022-2025 was 2% lower than in 2018-2021, peaking in 2022.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Antioxidant Activity and Oxidative Stress as a percentage of every work published that year, 0.023% in 2024.

still counting0.025%0.050%0.075%Antioxidant Activity and Oxidative Stress0.022% in 202519801990200020102020

Fractional works of Antioxidant Activity and Oxidative Stress over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Antioxidant Activity and Oxidative Stress10.1% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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