Genetics, Aging, and Longevity in Model Organisms
Genetics, Aging, and Longevity in Model Organisms is a research topic within Aging. Science Explorer counts 29k research works in it since 1950. 20.5% of them reached the world's top 10% most cited for their field and year.
This cluster of papers explores the molecular mechanisms underlying aging, longevity, and age-related diseases. It covers topics such as oxidative stress, genetic regulation of lifespan, the impact of caloric restriction, mitochondrial function, RNA interference, inflammaging, insulin signaling, and proteostasis. The research spans model organisms like C. elegans and Drosophila to mammalian studies, providing insights into the fundamental processes of aging.
- Aging
- Oxidative Stress
- Longevity
- Genetic Regulation
- Caloric Restriction
- Mitochondrial Function
- RNAi
- Inflammaging
- Insulin Signaling
- Proteostasis
- Research works
- 29k fractional, since 1950
- In the world top 10%
- 5.8k per year above
- Top-10% rate
- 20.5% share of its works in the world top 10%
- Growth, 2013–17 → 2018–22
- +22% the tick is no change
Which countries lead Genetics, Aging, and Longevity in Model Organisms research?
By volume, the United States and China publish the most (1.6k and 978 works in 2022–2025).
By volume, 2022–2025
- 1 United States 1.6k works
- 2 China 978 works
- 3 United Kingdom 208 works
- 4 Japan 203 works
- 5 Germany 200 works
- 6 India 196 works
- 7 Canada 153 works
- 8 France 144 works
- 9 South Korea 127 works
- 10 Spain 121 works
How concentrated that is
The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.
Shares of the rows listed above, not of the whole node.
Which institutions lead Genetics, Aging, and Longevity in Model Organisms research?
By volume in 2022–2025, Harvard University publishes the most Genetics, Aging, and Longevity in Model Organisms research, followed by University of California, Irvine and University of California San Diego.
By volume, 2022–2025
- 1 Harvard UniversityUnited States 30 works
- 2 University of California, IrvineUnited States 27 works
- 3 University of California San DiegoUnited States 24 works
- 4 University of Southern CaliforniaUnited States 23 works
- 5 University of PennsylvaniaUnited States 22 works
- 6 Centre National de la Recherche ScientifiqueFrance 21 works
- 7 University of MichiganUnited States 21 works
- 8 University of WashingtonUnited States 21 works
- 9 University of North Carolina at Chapel HillUnited States 21 works
- 10 Rockefeller UniversityUnited States 20 works
Who are the leading researchers in Genetics, Aging, and Longevity in Model Organisms?
The most-cited researchers publishing on Genetics, Aging, and Longevity in Model Organisms include Luigi Ferrucci, Steve Horvath and Brenda W.J.H. Penninx.
- 1 Luigi Ferrucci United States 5.3k citations
- 2 Steve Horvath United States 4.2k citations
- 3 Brenda W.J.H. Penninx Netherlands 4k citations
Ranked by citations received across their whole record, among researchers with at least three works on this topic.
Where is Genetics, Aging, and Longevity in Model Organisms research done?
The largest centres of Genetics, Aging, and Longevity in Model Organisms research in 2022–2025 are Beijing (China), New York (United States), Shanghai (China) and Paris (France). Among places with at least 20 works in it, it is an unusually large share of all research in Worcester and Irvine.
Largest cities, 2022–2025
Where it is the local speciality
- WorcesterUS · 23.9 works13×
- IrvineUS · 27.3 works8.6×
Location quotient: how much more of its research is in Genetics, Aging, and Longevity in Model Organisms than the world average.
Where is the best place to study Genetics, Aging, and Longevity in Model Organisms?
Among universities, judged by research, University of Massachusetts Chan Medical School, Southeast University and University of California San Diego score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.
One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.
| # | University | Score | Top 10% | Specialisation | Works | Growth |
|---|---|---|---|---|---|---|
| 1 | University of Massachusetts Chan Medical SchoolUnited States | 60.9 | 36.1% | 23.5× | 18 | +17.4% |
| 2 | Southeast UniversityChina | 53.6 | 54.6% | 2.9× | 20 | +0.7% |
| 3 | University of California San DiegoUnited States | 53.0 | 33.2% | 5.8× | 24 | +11.7% |
| 4 | Harvard UniversityUnited States | 51.0 | 25.3% | 4.9× | 30 | +1.0% |
| 5 | University of Southern CaliforniaUnited States | 48.6 | 20.3% | 6.5× | 23 | +55.1% |
| 6 | Albert Einstein College of MedicineUnited States | 47.4 | 16.4% | 14.1× | 13 | +45.0% |
| 7 | University of California, IrvineUnited States | 47.0 | 6.2% | 9.4× | 27 | 0.0% |
| 8 | University of Alabama at BirminghamUnited States | 46.3 | 22.8% | 7.4× | 17 | +36.7% |
| 9 | Rockefeller UniversityUnited States | 45.8 | 6.4% | 66.2× | 20 | +28.3% |
| 10 | Baylor College of MedicineUnited States | 44.3 | 19.7% | 7.8× | 15 | +44.7% |
Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.
Is Genetics, Aging, and Longevity in Model Organisms research growing?
Output in 2018–2022 was 22% higher than in 2013–2017, peaking in 2025. The fastest-growing topics are Genetics, Aging, and Longevity in Model Organisms.
The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.
Which topics inside it are moving
Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.