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Topic · Genetics

Ocular Disorders and Treatments

Ocular Disorders and Treatments is a research topic within Genetics. Science Explorer counts 14k research works in it since 1950. 10.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on genetic and clinical studies related to ocular development, particularly microphthalmia, anophthalmia, and associated syndromes such as Fraser syndrome. It explores the genetic mutations in genes like SOX2 and BCOR, as well as the use of orbital implants in surgical management of eye malformations. The research also delves into epidermal adhesion and its role in ocular development.

  • Ocular Development
  • Microphthalmia
  • Anophthalmia
  • Genetic Mutations
  • Fraser Syndrome
  • Orbital Implants
  • SOX2 Gene
  • BCOR Gene
  • Eye Malformations
  • Epidermal Adhesion
Research works
14k
fractional, since 1950
In the world top 10%
1.4k
per year above
Top-10% rate
10.0%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+7%
the tick is no change
Largest producer
United States
26% of the 10 largest, 2022-now
Ocular Disorders and Treatments

Which countries lead Ocular Disorders and Treatments research?

By volume, the United States and China publish the most (539 and 427 works in 2022-now).

By volume, 2022-now

  1. 1 United States 539 works
  2. 2 China 427 works
  3. 3 India 352 works
  4. 4 United Kingdom 145 works
  5. 5 Türkiye 110 works
  6. 6 Germany 110 works
  7. 7 Spain 106 works
  8. 8 Japan 96 works
  9. 9 Italy 92 works
  10. 10 Brazil 90 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 26.1%China: 20.7%India: 17.0%United Kingdom: 7.0%6 others listed: 29.2%26%largest
United States539 · 26.1%China427 · 20.7%India352 · 17.0%United Kingdom145 · 7.0%6 others listed603 · 29.2%

Shares of the rows listed above, not of the whole node.

Which institutions lead Ocular Disorders and Treatments research?

By volume in 2022-now, All India Institute of Medical Sciences publishes the most Ocular Disorders and Treatments research, followed by Capital Medical University and University College London.

By volume, 2022-now

  1. 1 All India Institute of Medical SciencesIndia 34 works
  2. 2 Capital Medical UniversityChina 26 works
  3. 3 University College LondonUnited Kingdom 24 works
  4. 4 L V Prasad Eye InstituteIndia 22 works
  5. 5 Aravind Eye HospitalIndia 22 works
  6. 6 Fudan UniversityChina 21 works
  7. 7 Sun Yat-sen UniversityChina 20 works
  8. 8 Harvard UniversityUnited States 19 works
  9. 9 Shanghai Jiao Tong UniversityChina 17 works
  10. 10 Tel Aviv UniversityIsrael 16 works

Who are the leading researchers in Ocular Disorders and Treatments?

The most-cited researchers publishing on Ocular Disorders and Treatments include Jost Bruno Jonas, Jun Wang and Richard A. Gibbs.

  1. 1 Jost Bruno Jonas Germany 350k citations
  2. 2 Jun Wang China 340k citations
  3. 3 Richard A. Gibbs United States 292k citations
  4. 4 Tien Yin Wong Singapore 237k citations
  5. 5 Dirk Schadendorf Germany 222k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Ocular Disorders and Treatments?

The most cited paper in Ocular Disorders and Treatments is "Updated national birth prevalence estimates for selected birth defects in the United States, 2004–2006" (Samantha E. Parker, Cara T. Mai, Mark A. Canfield et al., 2010), with 1,908 citations. Next come "Corneal Reconstruction with Tissue-Engineered Cell Sheets Composed of Autologous Oral Mucosal Epithelium" (1,537) and "Mutations in GNA11 in Uveal Melanoma" (1,503).

Most cited papers
#PaperReleasedCitations
1 Updated national birth prevalence estimates for selected birth defects in the United States, 2004–2006 Samantha E. Parker, Cara T. Mai, Mark A. Canfield et al. · Birth Defects Research Part A Clinical and Molecular Teratology 28 Sep 2010 1,908
2 Corneal Reconstruction with Tissue-Engineered Cell Sheets Composed of Autologous Oral Mucosal Epithelium Kohji Nishida, Masayuki Yamato, Yasutaka Hayashida et al. · New England Journal of Medicine Open access 15 Sep 2004 1,537
3 Mutations in GNA11 in Uveal Melanoma Catherine D. Van Raamsdonk, Klaus Griewank, Michelle B. Crosby et al. · New England Journal of Medicine Open access 17 Nov 2010 1,503
4 Control of Neuronal Precursor Proliferation in the Cerebellum by Sonic Hedgehog Robert J. Wechsler‐Reya, Matthew P. Scott · Neuron Open access 1999 1,403
5 Gene therapy restores vision in a canine model of childhood blindness Gregory M. Acland, Geoffrey K. Aguirre, Jharna Ray et al. · Nature Genetics May 2001 1,205
All 100 most cited papers, with filters and sorting

Where is Ocular Disorders and Treatments research done?

The largest centres of Ocular Disorders and Treatments research in 2022-now are Beijing (China), London (United Kingdom), Shanghai (China) and New Delhi (India). Among places with at least 20 works in it, it is an unusually large share of all research in Madurai and Hyderabad.

Largest cities, 2022-now

  1. 1 BeijingChina 73 works
  2. 2 LondonUnited Kingdom 58 works
  3. 3 ShanghaiChina 50 works
  4. 4 New DelhiIndia 43 works
  5. 5 IstanbulTürkiye 39 works
  6. 6 TokyoJapan 35 works
  7. 7 MoscowRussia 35 works
  8. 8 ChennaiIndia 33 works
  9. 9 GuangzhouChina 32 works
  10. 10 PhiladelphiaUnited States 32 works

Where it is the local speciality

  1. MaduraiIN · 22.7 works28×
  2. HyderabadIN · 26.2 works4.5×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Ocular Disorders and Treatments than the world average.

See Ocular Disorders and Treatments on the map

Where is the best place to study Ocular Disorders and Treatments?

Among universities, judged by research, University College London, Harvard University and Thomas Jefferson University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%mean 12.27%fractional works in this field (log) →share of work in the world top 10% →Harvard UniversityUniversity College L…Fudan UniversityThomas Jefferson Uni…
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1University College LondonUnited Kingdom 79.615.1%5.7×24 +3.9%
2Harvard UniversityUnited States 69.017.4%2.3×20 -11.5%
3Thomas Jefferson UniversityUnited States 64.96.8%24.8×14 +5.5%
4Fudan UniversityChina 60.911.4%4.9×20 +81.8%
5University of MiamiUnited States 60.416.8%9.0×15 -35.2%
6Shanghai Jiao Tong UniversityChina 59.720.3%2.2×17 -2.2%
7Capital Medical UniversityChina 58.68.1%9.3×26 +23.3%
8Johns Hopkins UniversityUnited States 51.411.4%2.7×11 -6.0%
9Wenzhou Medical UniversityChina 49.713.0%8.7×12 +51.1%
10All India Institute of Medical SciencesIndia 47.72.4%11.7×34 -0.4%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Ocular Disorders and Treatments, country by country

Is Ocular Disorders and Treatments research growing?

Output in 2022-2025 was 7% higher than in 2018-2021, peaking in 2026. The fastest-growing topics are Ocular Disorders and Treatments.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Ocular Disorders and Treatments as a percentage of every work published that year, 0.0099% in 2024.

still counting0.010%0.020%Ocular Disorders and Treatments0.011% in 202519801990200020102020

Fractional works of Ocular Disorders and Treatments over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Ocular Disorders and Treatments10.5% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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