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Company · Cambridge · United States

Agios Pharmaceuticals (United States)

agios.comROR OpenAlex
World rank, all time
#20,251
of 34,923
Rank in United States
#4,203
of 7,310
Research works
178
▼ 33% vs 2018-21
Citations
10k
59.0 per fractional work
Top-10% rate
13.8%
all institutions 10.0%
vs its own fields
1.08×
1.00× is exactly expected
Open access
42%
world 40%
International
29%
world 18%
Agios Pharmaceuticals (United States)

Which fields of science does Agios Pharmaceuticals (United States) work in?

In 2022-now, 61% of research at Agios Pharmaceuticals (United States) is in Health Sciences, 31% in Life Sciences. Its largest fields are Medicine (60%), Biochemistry, Genetics and Molecular Biology (26%), Pharmacology, Toxicology and Pharmaceutics (4%). It does 2.3× the world's share of Health Sciences.

Health Sciences: 27 fractional works · 61.0% of its workMedicine: 27 fractional works · 60.1% of its workHematology: 8 fractional works · 18.9% of its workPhysiology: 6 fractional works · 13.8% of its workGenetics: 6 fractional works · 13.2% of its workOncology: 1 fractional works · 3.2% of its workPediatrics, Perinatology and Child Health: 1 fractional works · 2.5% of its workEndocrinology, Diabetes and Metabolism: 1 fractional works · 1.2% of its workPulmonary and Respiratory Medicine: 0 fractional works · 1.0% of its workInfectious Diseases: 0 fractional works · 0.9% of its workEmergency Medicine: 0 fractional works · 0.9% of its workNephrology: 0 fractional works · 0.7% of its workPathology and Forensic Medicine: 0 fractional works · 0.7% of its workSurgery: 0 fractional works · 0.7% of its workBiochemistry: 0 fractional works · 0.7% of its workRheumatology: 0 fractional works · 0.5% of its workPublic Health, Environmental and Occupational Health: 0 fractional works · 0.3% of its workPharmacology: 0 fractional works · 0.3% of its workNeurology: 0 fractional works · 0.2% of its workPsychiatry and Mental health: 0 fractional works · 0.2% of its workHealth Professions: 0 fractional works · 0.7% of its workGeneral Health Professions: 0 fractional works · 0.3% of its workPharmacy: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.1% of its workVeterinary: 0 fractional works · 0.2% of its workLife Sciences: 14 fractional works · 31.4% of its workBiochemistry, Genetics and Molecular Biology: 12 fractional works · 26.4% of its workMolecular Biology: 4 fractional works · 9.9% of its workGenetics: 3 fractional works · 6.7% of its workCancer Research: 1 fractional works · 2.9% of its workCell Biology: 1 fractional works · 2.5% of its workBiochemistry: 1 fractional works · 1.9% of its workBiotechnology: 1 fractional works · 1.2% of its workClinical Biochemistry: 0 fractional works · 1.1% of its workPhysiology: 0 fractional works · 0.2% of its workPharmacology, Toxicology and Pharmaceutics: 2 fractional works · 3.8% of its workPharmacology: 2 fractional works · 3.6% of its workSmaller subfields together: 0 fractional works · 0.2% of its workImmunology and Microbiology: 1 fractional works · 1.2% of its workImmunology: 1 fractional works · 1.2% of its workSmaller subfields together: 0 fractional works · 0.1% of its workPhysical Sciences: 3 fractional works · 6.3% of its workChemistry: 1 fractional works · 2.0% of its workOrganic Chemistry: 1 fractional works · 1.5% of its workPhysical and Theoretical Chemistry: 0 fractional works · 0.4% of its workSmaller subfields together: 0 fractional works · 0.1% of its workComputer Science: 1 fractional works · 1.7% of its workComputational Theory and Mathematics: 1 fractional works · 1.3% of its workArtificial Intelligence: 0 fractional works · 0.4% of its workMaterials Science: 1 fractional works · 1.3% of its workMaterials Chemistry: 1 fractional works · 1.3% of its workEngineering: 0 fractional works · 1.0% of its workBiomedical Engineering: 0 fractional works · 0.4% of its workAutomotive Engineering: 0 fractional works · 0.4% of its workSmaller subfields together: 0 fractional works · 0.2% of its workMathematics: 0 fractional works · 0.4% of its workStatistics and Probability: 0 fractional works · 0.4% of its workSocial Sciences: 1 fractional works · 1.3% of its workEconomics, Econometrics and Finance: 0 fractional works · 0.5% of its workEconomics and Econometrics: 0 fractional works · 0.4% of its workSmaller subfields together: 0 fractional works · 0.1% of its workSocial Sciences: 0 fractional works · 0.3% of its workPsychology: 0 fractional works · 0.2% of its workClinical Psychology: 0 fractional works · 0.2% of its workBusiness, Management and Accounting: 0 fractional works · 0.2% of its workDecision Sciences: 0 fractional works · 0.1% of its workALL ITS WORKAgiosPharmaceuticals…45fractional works, 2022-now
Life Sciences31%Physical Sciences6%Health Sciences61%Social Sciences1%

Each ring splits the one inside it: the four domains of science, their fields, their subfields. Size is fractional works in 2022-now. Every slice is a page; the interactive view zooms down to single topics and colours each by how much more of it this institution does than the world.

Its 4 domains and 16 fields, with their numbers
    1. Medicine2760.1%
    2. Health Professions00.7%
    3. Veterinary00.2%
    1. Biochemistry, Genetics and Molecular Biology1226.4%
    2. Pharmacology, Toxicology and Pharmaceutics23.8%
    3. Immunology and Microbiology11.2%
    1. Chemistry12.0%
    2. Computer Science11.7%
    3. Materials Science11.3%
    4. Engineering01.0%
    5. Mathematics00.4%
    1. Economics, Econometrics and Finance00.5%
    2. Social Sciences00.3%
    3. Psychology00.2%
    4. Business, Management and Accounting00.2%
    5. Decision Sciences00.1%
All of science, and how each field's share has moved since 1950: the Science domain explorer

Field profile

Location quotient across every field it publishes in: outside the ring is more than an institution of this size would be expected to publish, inside it is less.

Biochemistry, Genetics and Molecular Biology: 4.95× its world share, 12 worksBiochemistry, Geneti…Immunology and Microbiology: 1.25× its world share, 1 worksImmunology and Micro…Pharmacology, Toxicology and Pharmaceutics: 10.69× its world share, 2 worksPharmacology, Toxico…Chemistry: 1.27× its world share, 1 worksChemistryComputer Science: 0.21× its world share, 1 worksComputer ScienceEngineering: 0.07× its world share, 0 worksEngineeringMaterials Science: 0.36× its world share, 1 worksMaterials ScienceMathematics: 0.32× its world share, 0 worksMathematicsHealth Professions: 0.26× its world share, 0 worksHealth ProfessionsMedicine: 3.13× its world share, 27 worksMedicineVeterinary: 1.37× its world share, 0 worksVeterinaryBusiness, Management and Accounting: 0.05× its world share, 0 worksBusiness, Management…Decision Sciences: 0.06× its world share, 0 worksDecision SciencesEconomics, Econometrics and Finance: 0.24× its world share, 0 worksEconomics, Econometr…Psychology: 0.08× its world share, 0 worksPsychologySocial Sciences: 0.02× its world share, 0 worksSocial Sciences1×world share
more than its size predictsabout as predictedless

Rings at 0.5×, 1× and 2×. Widest outward: Pharmacology, Toxicology and Pharmaceutics, 10.7×. Every wedge is a field page.

All 16 fields, with their numbers
  1. Pharmacology, Toxicology and Pharmaceutics10.69×2 works
  2. Biochemistry, Genetics and Molecular Biology4.95×12 works
  3. Medicine3.13×27 works
  4. Veterinary1.37×0 works
  5. Chemistry1.27×1 works
  6. Immunology and Microbiology1.25×1 works
  7. Materials Science0.36×1 works
  8. Mathematics0.32×0 works
  9. Health Professions0.26×0 works
  10. Economics, Econometrics and Finance0.24×0 works
  11. Computer Science0.21×1 works
  12. Psychology0.08×0 works
  13. Engineering0.07×0 works
  14. Decision Sciences0.06×0 works
  15. Business, Management and Accounting0.05×0 works
  16. Social Sciences0.02×0 works

Who are the top researchers at Agios Pharmaceuticals (United States)?

Ranked on the quality score, Shin-San Michael Su, Katharine E. Yen and Sung E. Choe lead among researchers whose main affiliation is Agios Pharmaceuticals (United States).

  1. 1 Shin-San Michael Su United States · #49,320 worldwide 14k citations · 44 works
  2. 2 Katharine E. Yen United States · #61,330 worldwide 18k citations · 125 works
  3. 3 Sung E. Choe United States · #91,037 worldwide 11k citations · 187 works
  4. 4 Lenny Dang United States · #102,905 worldwide 15k citations · 137 works
  5. 5 Edward M. Driggers United States · #135,926 worldwide 14k citations · 67 works
  6. 6 Marion Dorsch United States · #138,014 worldwide 9.2k citations · 152 works
  7. 7 Kimberly S. Straley United States · #170,678 worldwide 7.3k citations · 84 works
  8. 8 Victor Chubukov United States · #171,408 worldwide 3.7k citations · 52 works
  9. 9 Shengfang Jin United States · #186,068 worldwide 9.8k citations · 49 works
  10. 10 Brandon Nicolay United States · #223,741 worldwide 4.5k citations · 90 works
All ranked researchers at Agios Pharmaceuticals (United States)

What are the most cited papers from Agios Pharmaceuticals (United States)?

The most cited paper from Agios Pharmaceuticals (United States) is "Cancer-associated IDH1 mutations produce 2-hydroxyglutarate" (Lenny Dang, David W. White, Stefan Größ et al., 2009), with 4,209 citations. Next come "Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation" (2,793) and "Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization" (2,076).

Most cited papers
#PaperReleasedCitations
1 Cancer-associated IDH1 mutations produce 2-hydroxyglutarate Lenny Dang, David W. White, Stefan Größ et al. · Nature Open access 22 Nov 2009 4,209
2 Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation María E. Figueroa et al. · Cancer Cell Open access Dec 2010 2,793
3 Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization Abhishek Jha, Stanley Ching‐Cheng Huang, Alexey Sergushichev et al. · Immunity Open access Mar 2015 2,076
4 The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate Patrick S. Ward, Jay L. Patel, David R. Wise et al. · Cancer Cell Open access 22 Feb 2010 2,030
5 Functional genomics reveal that the serine synthesis pathway is essential in breast cancer Richard Possemato et al. · Nature Open access 14 Jul 2011 1,755
All 60 most cited papers, with filters and sorting

Which keywords describe research at Agios Pharmaceuticals (United States)?

By fractional works in 2022-now, weighted toward what it does more of than the world: Erythropoiesis, Ion Channels, Mechanotransduction, Apoptosis, Piezo1, Piezo2, Anemia and Sickle-cell Disease.

▲ more of its work than of the world's◆ about the world's share▼ less than the world's

Size is fractional works in 2022-now in the topics tagged with each word; colour is the word's share of this institution's work against its share of the world's. The 40 words are chosen for being large and distinctive. Each links to the topic it comes from most.

All 40 words, with their numbers
  1. Erythropoiesis7▲ 278×2 topics
  2. Ion Channels6▲ 124×3 topics
  3. Apoptosis6▲ 44×2 topics
  4. Mechanotransduction6▲ 206×2 topics
  5. Piezo16▲ 651×1 topic
  6. Piezo26▲ 651×1 topic
  7. Anemia6▲ 133×4 topics
  8. Epidemiology6▲ 3.1×2 topics
  9. Sickle-cell Disease5▲ 292×1 topic
  10. Thalassemia5▲ 292×1 topic
  11. Hematopoietic Stem Cells5▲ 119×2 topics
  12. Iron Deficiency4▲ 149×2 topics
  13. Inflammation3▲ 3.0×14 topics
  14. Cardiovascular Disease2▲ 5.0×4 topics
  15. Genetic Mutations2▲ 13×4 topics
  16. Prognostic Factors2▲ 13×3 topics
  17. AML2▲ 110×1 topic
  18. Acute Myeloid Leukemia2▲ 110×1 topic
  19. Chronic Kidney Disease2▲ 22×2 topics
  20. Heart Failure2▲ 12×3 topics
  21. Oxidative Stress2▲ 3.3×7 topics
  22. Congenital Disorders2▲ 342×1 topic
  23. Neutropenia2▲ 342×1 topic
  24. Stroke2▲ 28×2 topics
  25. Erythropoiesis-Stimulating Agents2▲ 362×1 topic
  26. Hypoxia-Inducible Factors2▲ 362×1 topic
  27. Neuroprotection2▲ 14×3 topics
  28. Alloimmunization2▲ 179×1 topic
  29. Blood Groups2▲ 179×1 topic
  30. Pancreatic Cancer2▲ 41×2 topics
  31. Pharmacokinetics2▲ 15×2 topics
  32. Cancer2▲ 2.8×11 topics
  33. Genetic Variants2▲ 20×3 topics
  34. Cytochrome P4501▲ 86×2 topics
  35. Hepcidin1▲ 78×1 topic
  36. Iron Regulation1▲ 78×1 topic
  37. Tumor Microenvironment1▲ 6.2×6 topics
  38. Drug Metabolism1▲ 102×1 topic
  39. Newborn Screening1▲ 54×2 topics
  40. Pharmacogenetics1▲ 138×1 topic

Which research topics does Agios Pharmaceuticals (United States) publish most on?

By volume in 2022-now: Erythrocyte Function and Pathophysiology, Hemoglobinopathies and Related Disorders, Acute Myeloid Leukemia Research and Blood disorders and treatments.

Erythrocyte Function and…6Erythrocyte Function and Pathophysiology: 6 fractional worksHemoglobinopathies and R…5Hemoglobinopathies and Related Disorders: 5 fractional worksAcute Myeloid Leukemia Research: 2 fractional worksBlood disorders and treatments: 2 fractional worksErythropoietin and Anemia Treatment: 2 fractional worksBlood groups and transfu…2Blood groups and transfusion: 2 fractional worksIron Metabolism and Disorders: 1 fractional worksPharmacogenetics and Drug Metabolism: 1 fractional worksHemoglobin structure and function: 1 fractional worksCancer, Hypoxia, and Metabolism: 1 fractional works
PhysiologyGeneticsHematologyPharmacology2 others

Area is fractional works; colour is the subfield each topic belongs to.

  1. 1 Erythrocyte Function and Pathophysiology Physiology 6 works
  2. 2 Hemoglobinopathies and Related Disorders Genetics 5 works
  3. 3 Acute Myeloid Leukemia Research Hematology 2 works
  4. 4 Blood disorders and treatments Genetics 2 works
  5. 5 Erythropoietin and Anemia Treatment Hematology 2 works
  6. 6 Blood groups and transfusion Hematology 2 works
  7. 7 Iron Metabolism and Disorders Hematology 1 works
  8. 8 Pharmacogenetics and Drug Metabolism Pharmacology 1 works
  9. 9 Hemoglobin structure and function Cell Biology 1 works
  10. 10 Cancer, Hypoxia, and Metabolism Cancer Research 1 works

How open and international is its research?

Against the world's own shares: the tick on each track. Both are shares of its output, so they sit on one scale and can be read against each other as well as against the world.

openly available41.9%not open58.1%

World: 40% of research is openly available.

with international co-authors28.9%domestic only71.1%

World: 18% is written across borders.

How has Agios Pharmaceuticals (United States)'s research output changed?

Output in 2022-2025 was 33% lower than in 2018-2021.

still counting200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Agios Pharmaceuticals (United States) as a percentage of every work published that year, 0.00019% in 2024.

still counting0.00020%0.00040%0.00060%Agios Pharmaceuticals (United States)0.000086% in 2025200020102020

Fractional works of Agios Pharmaceuticals (United States) over all fractional works that year. How the balance of science has shifted.

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Agios Pharmaceuticals (United States) on Science Explorer

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