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Company · Cambridge · United Kingdom

Bicycle Therapeutics (United Kingdom)

bicycletherapeutics.comROR OpenAlex
Research works
84
▲ 8% vs 2018-21
Citations
456
5.4 per fractional work
Top-10% rate
10.8%
all institutions 10.0%
Open access
37%
world 40%
International
24%
world 18%
Bicycle Therapeutics (United Kingdom)

Not ranked overall: Bicycle Therapeutics (United Kingdom) is under the volume floor below which a citation excellence rate is noise. Not ranked is not the same as ranked last.

Which fields of science does Bicycle Therapeutics (United Kingdom) work in?

In 2022-now, 44% of research at Bicycle Therapeutics (United Kingdom) is in Life Sciences, 25% in Health Sciences. Its largest fields are Medicine (25%), Biochemistry, Genetics and Molecular Biology (23%), Immunology and Microbiology (15%). It does 2.5× the world's share of Life Sciences.

Life Sciences: 18 fractional works · 44.2% of its workBiochemistry, Genetics and Molecular Biology: 9 fractional works · 22.6% of its workMolecular Biology: 7 fractional works · 17.5% of its workCell Biology: 1 fractional works · 2.3% of its workBiotechnology: 1 fractional works · 1.4% of its workStructural Biology: 0 fractional works · 0.6% of its workCancer Research: 0 fractional works · 0.3% of its workMolecular Medicine: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.2% of its workImmunology and Microbiology: 6 fractional works · 15.4% of its workImmunology: 6 fractional works · 13.7% of its workMicrobiology: 1 fractional works · 1.8% of its workNeuroscience: 2 fractional works · 5.1% of its workCellular and Molecular Neuroscience: 2 fractional works · 5.1% of its workPharmacology, Toxicology and Pharmaceutics: 0 fractional works · 1.0% of its workPharmacology: 0 fractional works · 0.8% of its workSmaller subfields together: 0 fractional works · 0.2% of its workHealth Sciences: 10 fractional works · 25.3% of its workMedicine: 10 fractional works · 25.3% of its workOncology: 4 fractional works · 9.3% of its workRadiology, Nuclear Medicine and Imaging: 3 fractional works · 7.3% of its workPathology and Forensic Medicine: 1 fractional works · 2.1% of its workPulmonary and Respiratory Medicine: 1 fractional works · 1.9% of its workPublic Health, Environmental and Occupational Health: 1 fractional works · 1.7% of its workSurgery: 0 fractional works · 1.0% of its workPhysiology: 0 fractional works · 0.5% of its workPharmacology: 0 fractional works · 0.5% of its workEndocrinology, Diabetes and Metabolism: 0 fractional works · 0.4% of its workSmaller subfields together: 0 fractional works · 0.6% of its workHealth Professions: 0 fractional works · 0.0% of its workPhysical Sciences: 8 fractional works · 19.8% of its workEngineering: 6 fractional works · 14.2% of its workIndustrial and Manufacturing Engineering: 2 fractional works · 5.0% of its workCivil and Structural Engineering: 1 fractional works · 3.0% of its workAutomotive Engineering: 1 fractional works · 2.8% of its workMechanical Engineering: 1 fractional works · 2.8% of its workElectrical and Electronic Engineering: 0 fractional works · 0.5% of its workBiomedical Engineering: 0 fractional works · 0.2% of its workChemistry: 1 fractional works · 3.1% of its workOrganic Chemistry: 1 fractional works · 2.9% of its workAnalytical Chemistry: 0 fractional works · 0.2% of its workPhysics and Astronomy: 0 fractional works · 1.0% of its workAtomic and Molecular Physics, and Optics: 0 fractional works · 1.0% of its workEnvironmental Science: 0 fractional works · 0.7% of its workEcology: 0 fractional works · 0.4% of its workPollution: 0 fractional works · 0.3% of its workMaterials Science: 0 fractional works · 0.6% of its workSurfaces, Coatings and Films: 0 fractional works · 0.6% of its workComputer Science: 0 fractional works · 0.0% of its workSocial Sciences: 4 fractional works · 10.8% of its workBusiness, Management and Accounting: 4 fractional works · 9.9% of its workManagement Information Systems: 3 fractional works · 7.5% of its workManagement of Technology and Innovation: 1 fractional works · 1.7% of its workStrategy and Management: 0 fractional works · 0.8% of its workPsychology: 0 fractional works · 0.8% of its workApplied Psychology: 0 fractional works · 0.8% of its workALL ITS WORKBicycleTherapeutics…40fractional works, 2022-now
Life Sciences44%Physical Sciences20%Health Sciences25%Social Sciences11%

Each ring splits the one inside it: the four domains of science, their fields, their subfields. Size is fractional works in 2022-now. Every slice is a page; the interactive view zooms down to single topics and colours each by how much more of it this institution does than the world.

Its 4 domains and 14 fields, with their numbers
    1. Biochemistry, Genetics and Molecular Biology922.6%
    2. Immunology and Microbiology615.4%
    3. Neuroscience25.1%
    4. Pharmacology, Toxicology and Pharmaceutics01.0%
    1. Medicine1025.3%
    2. Health Professions00.0%
    1. Engineering614.2%
    2. Chemistry13.1%
    3. Physics and Astronomy01.0%
    4. Environmental Science00.7%
    5. Materials Science00.6%
    6. Computer Science00.0%
    1. Business, Management and Accounting49.9%
    2. Psychology00.8%
All of science, and how each field's share has moved since 1950: the Science domain explorer

Field profile

Location quotient across every field it publishes in: outside the ring is more than an institution of this size would be expected to publish, inside it is less.

Biochemistry, Genetics and Molecular Biology: 4.24× its world share, 9 worksBiochemistry, Geneti…Immunology and Microbiology: 15.35× its world share, 6 worksImmunology and Micro…Neuroscience: 3.15× its world share, 2 worksNeurosciencePharmacology, Toxicology and Pharmaceutics: 2.79× its world share, 0 worksPharmacology, Toxico…Chemistry: 2.00× its world share, 1 worksChemistryComputer Science: 0.01× its world share, 0 worksComputer ScienceEngineering: 0.95× its world share, 6 worksEngineeringEnvironmental Science: 0.14× its world share, 0 worksEnvironmental ScienceMaterials Science: 0.18× its world share, 0 worksMaterials SciencePhysics and Astronomy: 0.47× its world share, 0 worksPhysics and AstronomyHealth Professions: 0.02× its world share, 0 worksHealth ProfessionsMedicine: 1.31× its world share, 10 worksMedicineBusiness, Management and Accounting: 3.08× its world share, 4 worksBusiness, Management…Psychology: 0.27× its world share, 0 worksPsychology1×world share
more than its size predictsabout as predictedless

Rings at 0.5×, 1× and 2×. Widest outward: Immunology and Microbiology, 15.3×. Every wedge is a field page.

All 14 fields, with their numbers
  1. Immunology and Microbiology15.35×6 works
  2. Biochemistry, Genetics and Molecular Biology4.24×9 works
  3. Neuroscience3.15×2 works
  4. Business, Management and Accounting3.08×4 works
  5. Pharmacology, Toxicology and Pharmaceutics2.79×0 works
  6. Chemistry2.00×1 works
  7. Medicine1.31×10 works
  8. Engineering0.95×6 works
  9. Physics and Astronomy0.47×0 works
  10. Psychology0.27×0 works
  11. Materials Science0.18×0 works
  12. Environmental Science0.14×0 works
  13. Health Professions0.02×0 works
  14. Computer Science0.01×0 works

Who are the top researchers at Bicycle Therapeutics (United Kingdom)?

Ranked on the quality score, Nicholas Keen, Johanna Lahdenranta and Kristen E. Hurov lead among researchers whose main affiliation is Bicycle Therapeutics (United Kingdom).

  1. 1 Nicholas Keen United Kingdom · #80,973 worldwide 11k citations · 149 works
  2. 2 Johanna Lahdenranta United Kingdom · #87,187 worldwide 6.3k citations · 159 works
  3. 3 Kristen E. Hurov United Kingdom · #337,970 worldwide 7.2k citations · 83 works
  4. 4 Gavin S. Bennett United Kingdom · #540,918 worldwide 3.4k citations · 68 works
  5. 5 Katerine Van Rietschoten United Kingdom · #578,959 worldwide 601 citations · 47 works
  6. 6 Gemma Mudd United Kingdom · #712,617 worldwide 686 citations · 79 works
  7. 7 Carly T. Campbell United Kingdom · #800,566 worldwide 525 citations · 46 works
  8. 8 Philip Huxley United Kingdom · #869,833 worldwide 772 citations · 36 works
  9. 9 Liuhong Chen United Kingdom · #1,076,971 worldwide 1.5k citations · 122 works
  10. 10 Amy N. Brown United Kingdom · #1,094,602 worldwide 666 citations · 44 works
All ranked researchers at Bicycle Therapeutics (United Kingdom)

What are the most cited papers from Bicycle Therapeutics (United Kingdom)?

The most cited paper from Bicycle Therapeutics (United Kingdom) is "Randomized Phase II Study Evaluating Palbociclib in Addition to Letrozole as Neoadjuvant Therapy in Estrogen Receptor–Positive Early Breast Cancer: PALLET Trial" (Stephen R.D. Johnston et al., 2018), with 239 citations. Next come "MMAE Delivery Using the Bicycle Toxin Conjugate BT5528" (102) and "BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors" (80).

Most cited papers
#PaperReleasedCitations
1 Randomized Phase II Study Evaluating Palbociclib in Addition to Letrozole as Neoadjuvant Therapy in Estrogen Receptor–Positive Early Breast Cancer: PALLET Trial Stephen R.D. Johnston et al. · Journal of Clinical Oncology Open access 6 Dec 2018 239
2 MMAE Delivery Using the Bicycle Toxin Conjugate BT5528 Gavin S. Bennett, Amy N. Brown, Gemma Mudd et al. · Molecular Cancer Therapeutics 12 May 2020 102
3 BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors Michael Rigby, Gavin S. Bennett, Liuhong Chen et al. · Molecular Cancer Therapeutics Open access 16 Sep 2022 80
4 Bicyclic Peptides with Optimized Ring Size Inhibit Human Plasma Kallikrein and its Orthologues While Sparing Paralogous Proteases Vanessa Baeriswyl, Helen Rapley, Lisa Pollaro et al. · ChemMedChem Open access 11 Apr 2012 73
5 Bicyclic Peptides as a New Modality for Imaging and Targeting of Proteins Overexpressed by Tumors Matthias Eder, Silvia Pavan, Ulrike Bauder‐Wüst et al. · Cancer Research 3 Jan 2019 69
All 86 most cited papers, with filters and sorting

Which keywords describe research at Bicycle Therapeutics (United Kingdom)?

By fractional works in 2022-now, weighted toward what it does more of than the world: Supply Chain Management, Glycosylation, Cancer Therapy, Big Data, Receptor tyrosine kinases, Monoclonal Antibodies, Therapeutic Antibodies and Antibody Engineering.

▲ more of its work than of the world's◆ about the world's share▼ less than the world's

Size is fractional works in 2022-now in the topics tagged with each word; colour is the word's share of this institution's work against its share of the world's. The 40 words are chosen for being large and distinctive. Each links to the topic it comes from most.

All 40 words, with their numbers
  1. Supply Chain Management6▲ 16×4 topics
  2. Glycosylation4▲ 88×3 topics
  3. Big Data3▲ 8.7×2 topics
  4. Cancer Therapy3▲ 15×6 topics
  5. Sustainability3▲ 3.4×2 topics
  6. Monoclonal Antibodies3▲ 79×3 topics
  7. Receptor tyrosine kinases3▲ 189×2 topics
  8. Antibody Engineering3▲ 128×1 topic
  9. Fc Receptors3▲ 128×1 topic
  10. Therapeutic Antibodies3▲ 101×2 topics
  11. Cell Signaling3▲ 42×4 topics
  12. Innate Immunity3▲ 20×2 topics
  13. Cancer Immunotherapy2▲ 39×2 topics
  14. Eph receptors2▲ 739×1 topic
  15. Semaphorins2▲ 739×1 topic
  16. Antigen Presentation2▲ 56×2 topics
  17. Digital Twin2▲ 36×1 topic
  18. Immunity2▲ 12×3 topics
  19. Smart Manufacturing2▲ 55×1 topic
  20. Dendritic Cells2▲ 52×1 topic
  21. Drug Discovery2▲ 21×5 topics
  22. Tumor Antigen2▲ 77×1 topic
  23. Tumor Microenvironment2▲ 10×3 topics
  24. Enterprise Resource Planning2▲ 551×1 topic
  25. Implementation Procedures2▲ 551×1 topic
  26. NK Cell Recognition2▲ 70×1 topic
  27. Natural Killer Cells2▲ 70×1 topic
  28. Angiogenesis2▲ 12×4 topics
  29. Immunotherapy1▲ 4.9×5 topics
  30. Analytics1▲ 38×1 topic
  31. Breast Cancer1▲ 13×3 topics
  32. Business Intelligence1▲ 38×1 topic
  33. PET Imaging1▲ 20×2 topics
  34. Fibroblast Activation Protein1▲ 71×1 topic
  35. Gene Therapy1▲ 15×2 topics
  36. Immunosuppression1▲ 34×1 topic
  37. Monoclonal Antibody1▲ 56×2 topics
  38. Phosphorylation1▲ 116×2 topics
  39. Targeted Therapy1▲ 13×3 topics
  40. Cancer Progression1▲ 15×4 topics

Which research topics does Bicycle Therapeutics (United Kingdom) publish most on?

By volume in 2022-now: Monoclonal and Polyclonal Antibodies Research, Axon Guidance and Neuronal Signaling, Digital Transformation in Industry and Immunotherapy and Immune Responses.

Monoclonal and Polyclona…3Monoclonal and Polyclonal Antibodies Research: 3 fractional worksAxon Guidance and Neuron…2Axon Guidance and Neuronal Signaling: 2 fractional worksDigital Transformation i…2Digital Transformation in Industry: 2 fractional worksImmunotherapy and Immune…2Immunotherapy and Immune Responses: 2 fractional worksERP Systems Implementation and Impact: 2 fractional worksImmune Cell Function and Interaction: 2 fractional worksBig Data and Business In…1Big Data and Business Intelligence: 1 fractional worksPeptidase Inhibition and Analysis: 1 fractional worksVehicle Dynamics and Control Systems: 1 fractional worksSoil Mechanics and Vehicle Dynamics: 1 fractional works
Radiology, Nuclear Medicine and ImagingCellular and Molecular NeuroscienceIndustrial and Manufacturing EngineeringImmunology4 others

Area is fractional works; colour is the subfield each topic belongs to.

  1. 1 Monoclonal and Polyclonal Antibodies Research Radiology, Nuclear Medicine and Imaging 3 works
  2. 2 Axon Guidance and Neuronal Signaling Cellular and Molecular Neuroscience 2 works
  3. 3 Digital Transformation in Industry Industrial and Manufacturing Engineering 2 works
  4. 4 Immunotherapy and Immune Responses Immunology 2 works
  5. 5 ERP Systems Implementation and Impact Management Information Systems 2 works
  6. 6 Immune Cell Function and Interaction Immunology 2 works
  7. 7 Big Data and Business Intelligence Management Information Systems 1 works
  8. 8 Peptidase Inhibition and Analysis Oncology 1 works
  9. 9 Vehicle Dynamics and Control Systems Automotive Engineering 1 works
  10. 10 Soil Mechanics and Vehicle Dynamics Civil and Structural Engineering 1 works

How open and international is its research?

Against the world's own shares: the tick on each track. Both are shares of its output, so they sit on one scale and can be read against each other as well as against the world.

openly available36.6%not open63.4%

World: 40% of research is openly available.

with international co-authors24.2%domestic only75.8%

World: 18% is written across borders.

How has Bicycle Therapeutics (United Kingdom)'s research output changed?

Output in 2022-2025 was 8% higher than in 2018-2021.

still counting200020052010201520202025
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Bicycle Therapeutics (United Kingdom) as a percentage of every work published that year, 0.000084% in 2024.

still counting0.00010%0.00020%Bicycle Therapeutics (United Kingdom)0.000084% in 2025200020102020

Fractional works of Bicycle Therapeutics (United Kingdom) over all fractional works that year. How the balance of science has shifted.

Other research institutions in Cambridge

All research institutions in Cambridge

Research measures only: rankings here say nothing about teaching, admissions or student experience. Comparable institutions and collaboration partners have tabs of their own, above.

Discussion

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