Click Chemistry and Applications
Click Chemistry and Applications is a research topic within Organic Chemistry. Science Explorer counts 36k research works in it since 1950. 18.1% of them reached the world's top 10% most cited for their field and year.
This cluster of papers focuses on the application of click chemistry, particularly the copper-catalyzed azide-alkyne cycloaddition, in chemical biology and drug development. It explores diverse chemical functionality, bioorthogonal chemistry, protein labeling, in vivo imaging, triazole synthesis, and the development of enzyme inhibitors.
- Click Chemistry
- Copper-Catalyzed Cycloaddition
- Bioorthogonal Chemistry
- Azides and Alkynes
- Chemical Functionality
- Drug Discovery
- Protein Labeling
- In Vivo Imaging
- Triazole Synthesis
- Enzyme Inhibitors
- Research works
- 36k fractional, since 1950
- In the world top 10%
- 6.5k per year above
- Top-10% rate
- 18.1% share of its works in the world top 10%
- Growth, 2013–17 → 2018–22
- +1% the tick is no change
Which countries lead Click Chemistry and Applications research?
By volume, China and India publish the most (1.2k and 899 works in 2022–2025).
By volume, 2022–2025
- 1 China 1.2k works
- 2 India 899 works
- 3 United States 822 works
- 4 Germany 230 works
- 5 Japan 208 works
- 6 France 174 works
- 7 Russia 169 works
- 8 United Kingdom 161 works
- 9 Egypt 141 works
- 10 Türkiye 129 works
How concentrated that is
The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.
Shares of the rows listed above, not of the whole node.
Which institutions lead Click Chemistry and Applications research?
By volume in 2022–2025, Centre National de la Recherche Scientifique publishes the most Click Chemistry and Applications research, followed by Chinese Academy of Sciences and National Research Centre.
By volume, 2022–2025
- 1 Centre National de la Recherche Scientifique France 31 works
- 2 Chinese Academy of Sciences China 28 works
- 3 National Research Centre Egypt 23 works
- 4 Peking University China 21 works
- 5 Sichuan University China 20 works
- 6 Banaras Hindu University India 20 works
- 7 University of Chinese Academy of Sciences China 19 works
- 8 Vellore Institute of Technology University India 17 works
- 9 Sun Yat-sen University China 17 works
- 10 University of North Carolina at Chapel Hill United States 17 works
Who are the leading researchers in Click Chemistry and Applications?
The most-cited researchers publishing on Click Chemistry and Applications include Ben Zhong Tang, Wei Huang and Dirk Schadendorf.
- 1 Ben Zhong Tang 7k citations
- 2 Wei Huang 5.5k citations
- 3 Dirk Schadendorf 4.4k citations
- 4 Stephen L. Buchwald 3.5k citations
- 5 Harold A. Scheraga 3.3k citations
Ranked by citations received across their whole record, among researchers with at least three works on this topic.
Where is Click Chemistry and Applications research done?
The largest centres of Click Chemistry and Applications research in 2022–2025 are Beijing (China), Shanghai (China), Moscow (Russia) and Guangzhou (China).
Where is the best place to study Click Chemistry and Applications?
Among universities, judged by research, Guru Jambheshwar University of Science and Technology, Al-Azhar University and Osmania University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.
One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.
| # | University | Score | Top 10% | Specialisation | Works | Growth |
|---|---|---|---|---|---|---|
| 1 | Guru Jambheshwar University of Science and Technology India | 74.7 | 39.4% | 36.3× | 14 | +391.2% |
| 2 | Al-Azhar University Egypt | 69.6 | 38.7% | 6.4× | 14 | +268.8% |
| 3 | Osmania University India | 60.3 | 16.8% | 22.2× | 16 | +221.7% |
| 4 | Banaras Hindu University India | 58.6 | 28.3% | 7.6× | 20 | +65.7% |
| 5 | Vellore Institute of Technology University India | 55.2 | 33.2% | 3.0× | 17 | +214.9% |
| 6 | China Pharmaceutical University China | 53.1 | 22.0% | 13.6× | 16 | -0.4% |
| 7 | Shenyang Pharmaceutical University China | 52.6 | 24.3% | 14.5× | 11 | +76.3% |
| 8 | Leiden University Netherlands | 52.3 | 39.0% | 4.9× | 9 | +73.2% |
| 9 | Academy of Scientific and Innovative Research India | 51.6 | 7.8% | 9.0× | 16 | +274.1% |
| 10 | Cairo University Egypt | 51.0 | 40.4% | 3.7× | 16 | -16.8% |
Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.
Is Click Chemistry and Applications research growing?
Output in 2018–2022 was 1% higher than in 2013–2017, peaking in 2025. The fastest-growing topics are Click Chemistry and Applications.
The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.
Which topics inside it are moving
Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.