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Topic · Biomaterials

Collagen: Extraction and Characterization

Collagen: Extraction and Characterization is a research topic within Biomaterials. Science Explorer counts 15k research works in it since 1950. 10.1% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the structure, stability, extraction, and biomedical applications of collagen and gelatin. It covers topics such as collagen-based biomaterials for tissue engineering, mechanical properties of collagen fibrils, and the use of collagen in wound healing and drug delivery. The research also explores alternative sources of collagen, such as fish gelatin, and their potential for various biomedical applications.

  • Collagen
  • Biomaterials
  • Tissue Engineering
  • Gelatin
  • Structure
  • Stability
  • Extraction
  • Characterization
  • Biomedical Applications
  • Mechanical Properties
Research works
15k
fractional, since 1950
In the world top 10%
1.5k
per year above
Top-10% rate
10.1%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+30%
the tick is no change
Largest producer
China
36% of the 10 largest, 2022-now
Collagen: Extraction and Characterization

Which countries lead Collagen: Extraction and Characterization research?

By volume, China and the United States publish the most (642 and 240 works in 2022-now).

By volume, 2022-now

  1. 1 China 642 works
  2. 2 United States 240 works
  3. 3 Indonesia 231 works
  4. 4 India 208 works
  5. 5 Russia 103 works
  6. 6 Japan 85 works
  7. 7 Türkiye 85 works
  8. 8 Brazil 74 works
  9. 9 Italy 64 works
  10. 10 South Korea 58 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 35.9%United States: 13.4%Indonesia: 12.9%India: 11.6%6 others listed: 26.2%36%largest
China642 · 35.9%United States240 · 13.4%Indonesia231 · 12.9%India208 · 11.6%6 others listed469 · 26.2%

Shares of the rows listed above, not of the whole node.

Which institutions lead Collagen: Extraction and Characterization research?

By volume in 2022-now, Sichuan University publishes the most Collagen: Extraction and Characterization research, followed by Council of Scientific and Industrial Research and Russian Academy of Sciences.

By volume, 2022-now

  1. 1 Sichuan UniversityChina 45 works
  2. 2 Council of Scientific and Industrial ResearchIndia 26 works
  3. 3 Russian Academy of SciencesRussia 24 works
  4. 4 Centre National de la Recherche ScientifiqueFrance 22 works
  5. 5 Shaanxi University of Science and TechnologyChina 19 works
  6. 6 Universitas Teknologi YogyakartaIndonesia 19 works
  7. 7 Universitas Gadjah MadaIndonesia 17 works
  8. 8 University of DhakaBangladesh 15 works
  9. 9 Chinese Academy of SciencesChina 14 works
  10. 10 Chinese Academy of Agricultural SciencesChina 14 works

Who are the leading researchers in Collagen: Extraction and Characterization?

The most-cited researchers publishing on Collagen: Extraction and Characterization include Róbert Langer, André Gerardus Uitterlinden and Kai You Wang.

  1. 1 Róbert Langer United States 303k citations
  2. 2 André Gerardus Uitterlinden Netherlands 246k citations
  3. 3 Kai You Wang China 224k citations
  4. 4 Douglas Hanahan United States 191k citations
  5. 5 Hongjie Dai United States 189k citations
  6. 6 Seeram Ramakrishna Singapore 186k citations
  7. 7 David Julian McClements United States 185k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Collagen: Extraction and Characterization?

The most cited paper in Collagen: Extraction and Characterization is "Molecular Mechanisms of Stress-Responsive Changes in Collagen and Elastin Networks in Skin" (Jazli Aziz, Hafiz Shezali, Zamri Radzi et al., 2016), with 7,308 citations. Next come "Collagen Structure and Stability" (3,926) and "Collagens—structure, function, and biosynthesis" (2,643).

Most cited papers
#PaperReleasedCitations
1 Molecular Mechanisms of Stress-Responsive Changes in Collagen and Elastin Networks in Skin Jazli Aziz, Hafiz Shezali, Zamri Radzi et al. · Skin Pharmacology and Physiology 2016 7,308
2 Collagen Structure and Stability Matthew D. Shoulders, Ronald T. Raines · Annual Review of Biochemistry ReviewOpen access 3 Apr 2009 3,926
3 Collagens—structure, function, and biosynthesis Kolja Gelse · Advanced Drug Delivery Reviews 29 Oct 2003 2,643
4 Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections L. C. U. Junqueira, G. Bignolas, Helena Brentani · The Histochemical Journal Jul 1979 2,602
5 Biphasic Creep and Stress Relaxation of Articular Cartilage in Compression: Theory and Experiments Van C. Mow, S. C. Kuei, W. M. Lai et al. · Journal of Biomechanical Engineering Feb 1980 2,476
All 100 most cited papers, with filters and sorting

Where is Collagen: Extraction and Characterization research done?

The largest centres of Collagen: Extraction and Characterization research in 2022-now are Beijing (China), Chengdu (China), Chennai (India) and Xi'an (China). Among places with at least 20 works in it, it is an unusually large share of all research in Bucharest.

Largest cities, 2022-now

  1. 1 BeijingChina 79 works
  2. 2 ChengduChina 54 works
  3. 3 ChennaiIndia 48 works
  4. 4 Xi'anChina 38 works
  5. 5 MoscowRussia 34 works
  6. 6 DhakaBangladesh 32 works
  7. 7 ShanghaiChina 32 works
  8. 8 BucharestRomania 27 works
  9. 9 YogyakartaIndonesia 25 works
  10. 10 WuhanChina 24 works

Where it is the local speciality

  1. BucharestRO · 27.4 works6.6×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Collagen: Extraction and Characterization than the world average.

See Collagen: Extraction and Characterization on the map

Where is the best place to study Collagen: Extraction and Characterization?

Among universities, judged by research, Shaanxi University of Science and Technology, Sichuan University and Dalian Polytechnic University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 16.31%fractional works in this field (log) →share of work in the world top 10% →Shaanxi University o…Dalian Polytechnic U…Jiangnan UniversitySichuan University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Shaanxi University of Science and TechnologyChina 73.232.9%31.8×19 +27.8%
2Sichuan UniversityChina 65.216.8%8.1×45 -11.2%
3Dalian Polytechnic UniversityChina 63.222.8%26.5×11 +119.9%
4Jiangnan UniversityChina 57.218.8%7.5×11 +55.9%
5Nanchang UniversityChina 54.311.7%6.8×12 +81.8%
6Shanghai Jiao Tong UniversityChina 52.926.6%1.1×8 +19.8%
7Lanzhou UniversityChina 46.911.4%7.5×13 +215.5%
8University of DhakaBangladesh 46.47.6%17.0×15 +79.3%
9Saveetha UniversityIndia 43.514.5%4.1×10 -
10Universitas Teknologi YogyakartaIndonesia 34.50.0%41.4×18 +218.9%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Collagen: Extraction and Characterization, country by country

Is Collagen: Extraction and Characterization research growing?

Output in 2022-2025 was 30% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Collagen: Extraction and Characterization.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Collagen: Extraction and Characterization as a percentage of every work published that year, 0.011% in 2024.

still counting0.020%0.040%Collagen: Extraction and Characterization0.012% in 202519801990200020102020

Fractional works of Collagen: Extraction and Characterization over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Collagen: Extraction and Characterization10.3% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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