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Topic · Organic Chemistry

Cyclopropane Reaction Mechanisms

Cyclopropane Reaction Mechanisms is a research topic within Organic Chemistry. Science Explorer counts 29k research works in it since 1950. 9.8% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the catalytic carbene chemistry in organic synthesis, particularly on the use of donor-acceptor cyclopropanes, diazo compounds, and metal-catalyzed reactions. It covers topics such as enantioselective synthesis, site-selective functionalization, and the development of artificial metalloenzymes for carbene transfer reactions.

  • Carbene Chemistry
  • Cyclopropanation
  • Metal-Catalyzed Reactions
  • Donor-Acceptor Cyclopropanes
  • Enantioselective Synthesis
  • Rhodium-Catalyzed Reactions
  • Diazo Compounds
  • Artificial Metalloenzymes
  • Site-Selective Functionalization
  • Transition-Metal Chemistry
Research works
29k
fractional, since 1950
In the world top 10%
2.8k
per year above
Top-10% rate
9.8%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-4%
the tick is no change
Largest producer
China
51% of the 10 largest, 2022-now
Cyclopropane Reaction Mechanisms

Which countries lead Cyclopropane Reaction Mechanisms research?

By volume, China and India publish the most (1.4k and 354 works in 2022-now).

By volume, 2022-now

  1. 1 China 1.4k works
  2. 2 India 354 works
  3. 3 United States 314 works
  4. 4 Japan 146 works
  5. 5 Germany 141 works
  6. 6 Russia 114 works
  7. 7 France 102 works
  8. 8 Spain 87 works
  9. 9 United Kingdom 61 works
  10. 10 South Korea 40 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 50.7%India: 12.8%United States: 11.4%Japan: 5.3%6 others listed: 19.8%51%largest
China1,396 · 50.7%India354 · 12.8%United States314 · 11.4%Japan146 · 5.3%6 others listed545 · 19.8%

Shares of the rows listed above, not of the whole node.

Which institutions lead Cyclopropane Reaction Mechanisms research?

By volume in 2022-now, Chinese Academy of Sciences publishes the most Cyclopropane Reaction Mechanisms research, followed by Centre National de la Recherche Scientifique and Russian Academy of Sciences.

By volume, 2022-now

  1. 1 Chinese Academy of SciencesChina 116 works
  2. 2 Centre National de la Recherche ScientifiqueFrance 56 works
  3. 3 Russian Academy of SciencesRussia 51 works
  4. 4 Henan Normal UniversityChina 39 works
  5. 5 Sichuan UniversityChina 35 works
  6. 6 Nankai UniversityChina 32 works
  7. 7 Council of Scientific and Industrial ResearchIndia 31 works
  8. 8 Sun Yat-sen UniversityChina 29 works
  9. 9 Academy of Scientific and Innovative ResearchIndia 27 works
  10. 10 University of Chinese Academy of SciencesChina 26 works

Who are the leading researchers in Cyclopropane Reaction Mechanisms?

The most-cited researchers publishing on Cyclopropane Reaction Mechanisms include Christopher J L Murray, George M. Whitesides and Wei Huang.

  1. 1 Christopher J L Murray United States 583k citations
  2. 2 George M. Whitesides United States 267k citations
  3. 3 Wei Huang China 267k citations
  4. 4 Donald G. Truhlar United States 230k citations
  5. 5 Stefan Grimme Germany 224k citations
  6. 6 Kai You Wang China 224k citations
  7. 7 George M. Sheldrick Germany 220k citations
  8. 8 Trevor William Robbins United Kingdom 199k citations
  9. 9 Qiang Zhang China 184k citations
  10. 10 William A. Goddard United States 182k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Cyclopropane Reaction Mechanisms?

The most cited paper in Cyclopropane Reaction Mechanisms is "An overview of N-heterocyclic carbenes" (Matthew N. Hopkinson, Christian Paolo Richter, Michael Schedler et al., 2014), with 4,281 citations. Next come "Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation" (3,695) and "Aryl−Aryl Bond Formation One Century after the Discovery of the Ullmann Reaction" (3,659).

Most cited papers
#PaperReleasedCitations
1 An overview of N-heterocyclic carbenes Matthew N. Hopkinson, Christian Paolo Richter, Michael Schedler et al. · Nature Jun 2014 4,281
2 Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation Denise A. Colby, Robert George Bergman, Jonathan A. Ellman · Chemical Reviews ReviewOpen access 13 May 2009 3,695
3 Aryl−Aryl Bond Formation One Century after the Discovery of the Ullmann Reaction Jwanro Hassan, Marc Sévignon, Christel Gozzi et al. · Chemical Reviews Review 8 Mar 2002 3,659
4 Aryl−Aryl Bond Formation by Transition-Metal-Catalyzed Direct Arylation Dino Alberico, Mark E. Scott, Mark Lautens · Chemical Reviews Review 2007 3,637
5 Stable Carbenes Didier Bourissou, Olivier Guerret, François P. Gabbaı̈ et al. · Chemical Reviews Review 22 Dec 1999 3,607
All 100 most cited papers, with filters and sorting

Where is Cyclopropane Reaction Mechanisms research done?

The largest centres of Cyclopropane Reaction Mechanisms research in 2022-now are Beijing (China), Shanghai (China), Guangzhou (China) and Hangzhou (China). Among places with at least 20 works in it, it is an unusually large share of all research in Xinxiang, Ghaziabad and Changzhou.

Largest cities, 2022-now

  1. 1 BeijingChina 163 works
  2. 2 ShanghaiChina 124 works
  3. 3 GuangzhouChina 80 works
  4. 4 HangzhouChina 76 works
  5. 5 NanjingChina 72 works
  6. 6 TianjinChina 57 works
  7. 7 ChengduChina 56 works
  8. 8 MoscowRussia 51 works
  9. 9 XinxiangChina 45 works
  10. 10 WuhanChina 40 works

Where it is the local speciality

  1. XinxiangCN · 44.6 works50×
  2. GhaziabadIN · 26.8 works18×
  3. ChangzhouCN · 22.0 works15×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Cyclopropane Reaction Mechanisms than the world average.

See Cyclopropane Reaction Mechanisms on the map

Where is the best place to study Cyclopropane Reaction Mechanisms?

Among universities, judged by research, Henan Normal University, Nankai University and Southern University of Science and Technology score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 21.12%fractional works in this field (log) →share of work in the world top 10% →Nankai UniversitySouthern University …Henan Normal Univers…École Polytechnique …
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Henan Normal UniversityChina 81.221.3%72.9×39 +120.1%
2Nankai UniversityChina 79.727.1%17.2×32 +1.8%
3Southern University of Science and TechnologyChina 73.922.4%11.7×17 +54.8%
4École Polytechnique Fédérale de LausanneSwitzerland 69.715.0%15.0×17 +4.3%
5Wuhan UniversityChina 63.933.9%3.3×13 +27.5%
6Indian Institute of Science BangaloreIndia 62.928.5%12.2×13 +55.0%
7Nanjing Tech UniversityChina 59.218.7%12.9×17 +40.3%
8Northeast Normal UniversityChina 58.620.2%26.6×15 +29.7%
9Sichuan UniversityChina 58.213.1%5.8×35 -7.6%
10Sun Yat-sen UniversityChina 55.611.0%5.1×29 +4.3%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Cyclopropane Reaction Mechanisms, country by country

Is Cyclopropane Reaction Mechanisms research growing?

Output in 2022-2025 was 4% lower than in 2018-2021, peaking in 2016.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Cyclopropane Reaction Mechanisms as a percentage of every work published that year, 0.012% in 2024.

still counting0.020%0.040%0.060%Cyclopropane Reaction Mechanisms0.012% in 202519801990200020102020

Fractional works of Cyclopropane Reaction Mechanisms over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Cyclopropane Reaction Mechanisms9.8% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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