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Topic · Virology

HIV Research and Treatment

HIV Research and Treatment is a research topic within Virology. Science Explorer counts 58k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on various aspects of HIV/AIDS, including immune activation, vaccine development, viral reservoirs, antiretroviral therapy, and the immune response to HIV infection. It also covers topics related to neurocognitive disorders associated with HIV, antibodies targeting HIV, and the development of potential therapeutic interventions.

  • HIV
  • AIDS
  • vaccine
  • antibodies
  • immune activation
  • neurocognitive disorders
  • viral reservoir
  • T cell
  • antiretroviral therapy
  • immune response
Research works
58k
fractional, since 1950
In the world top 10%
5.8k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-20%
the tick is no change
Largest producer
United States
48% of the 10 largest, 2022-now
HIV Research and Treatment

Which countries lead HIV Research and Treatment research?

By volume, the United States and China publish the most (2.1k and 775 works in 2022-now).

By volume, 2022-now

  1. 1 United States 2.1k works
  2. 2 China 775 works
  3. 3 India 231 works
  4. 4 United Kingdom 230 works
  5. 5 France 220 works
  6. 6 Italy 197 works
  7. 7 South Africa 183 works
  8. 8 Spain 162 works
  9. 9 Canada 156 works
  10. 10 Germany 138 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 48.4%China: 17.5%India: 5.2%United Kingdom: 5.2%6 others listed: 23.8%48%largest
United States2,149 · 48.4%China775 · 17.5%India231 · 5.2%United Kingdom230 · 5.2%6 others listed1,057 · 23.8%

Shares of the rows listed above, not of the whole node.

Which institutions lead HIV Research and Treatment research?

By volume in 2022-now, University of North Carolina at Chapel Hill publishes the most HIV Research and Treatment research, followed by National Institutes of Health and Harvard University.

By volume, 2022-now

  1. 1 University of North Carolina at Chapel HillUnited States 136 works
  2. 2 National Institutes of HealthUnited States 105 works
  3. 3 Harvard UniversityUnited States 92 works
  4. 4 Johns Hopkins UniversityUnited States 72 works
  5. 5 Emory UniversityUnited States 43 works
  6. 6 InsermFrance 42 works
  7. 7 Centre National de la Recherche ScientifiqueFrance 42 works
  8. 8 University of California San DiegoUnited States 41 works
  9. 9 Capital Medical UniversityChina 40 works
  10. 10 University of California, San FranciscoUnited States 38 works

Who are the leading researchers in HIV Research and Treatment?

The most-cited researchers publishing on HIV Research and Treatment include Christopher J L Murray, Eric S. Lander and Rob Knight.

  1. 1 Christopher J L Murray United States 583k citations
  2. 2 Eric S. Lander United States 524k citations
  3. 3 Rob Knight United States 468k citations
  4. 4 Simon Iain Hay United States 452k citations
  5. 5 George Davey Smith United Kingdom 435k citations
  6. 6 Ali H. Mokdad United States 429k citations
  7. 7 Guido Kroemer France 386k citations
  8. 8 Jost Bruno Jonas Germany 350k citations
  9. 9 Shizuo Akira Japan 342k citations
  10. 10 Cyrus Cooper United Kingdom 342k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in HIV Research and Treatment?

The most cited paper in HIV Research and Treatment is "AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility" (Garrett M. Morris, Ruth Huey, William Lindstrom et al., 2009), with 25,864 citations. Next come "Prevention of HIV-1 Infection with Early Antiretroviral Therapy" (7,006) and "1993 Revised Classification System for HIV Infection and Expanded Surveillance Case Definition for AIDS Among Adolescents and Adults" (4,364).

Most cited papers
#PaperReleasedCitations
1 AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility Garrett M. Morris, Ruth Huey, William Lindstrom et al. · Journal of Computational Chemistry Open access 27 Apr 2009 25,864
2 Prevention of HIV-1 Infection with Early Antiretroviral Therapy Myron S. Cohen et al. · New England Journal of Medicine Open access 18 Jul 2011 7,006
3 1993 Revised Classification System for HIV Infection and Expanded Surveillance Case Definition for AIDS Among Adolescents and Adults Kenneth G. Castro, Jill Ward, Laurence Slutsker et al. · Clinical Infectious Diseases Oct 1993 4,364
4 Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection David D. Ho, Avidan Uriel Neumann, Alan S. Perelson et al. · Nature 1995 4,310
5 Reduction of Maternal-Infant Transmission of Human Immunodeficiency Virus Type 1 with Zidovudine Treatment Edward M. Connor, RHODA S. SPERLING, Richard D. Gelber et al. · New England Journal of Medicine Open access 3 Nov 1994 3,755
All 100 most cited papers, with filters and sorting

Where is HIV Research and Treatment research done?

The largest centres of HIV Research and Treatment research in 2022-now are Beijing (China), Chapel Hill (United States), Paris (France) and London (United Kingdom). Among places with at least 20 works in it, it is an unusually large share of all research in Kampala, Bethesda and Chapel Hill.

Largest cities, 2022-now

  1. 1 BeijingChina 170 works
  2. 2 Chapel HillUnited States 135 works
  3. 3 ParisFrance 118 works
  4. 4 LondonUnited Kingdom 112 works
  5. 5 New YorkUnited States 102 works
  6. 6 BethesdaUnited States 98 works
  7. 7 BaltimoreUnited States 93 works
  8. 8 AtlantaUnited States 90 works
  9. 9 SeattleUnited States 77 works
  10. 10 PhiladelphiaUnited States 74 works

Where it is the local speciality

  1. KampalaUG · 46.7 works17×
  2. BethesdaUS · 98.3 works14×
  3. Chapel HillUS · 135.5 works12×
← less than its size predicts1×more →

Location quotient: how much more of its research is in HIV Research and Treatment than the world average.

See HIV Research and Treatment on the map

Where is the best place to study HIV Research and Treatment?

Among universities, judged by research, Harvard University, Rockefeller University and University of California, San Francisco score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%mean 13.33%fractional works in this field (log) →share of work in the world top 10% →Rockefeller UniversityHarvard UniversityUniversity of Califo…Johns Hopkins Univer…
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Harvard UniversityUnited States 68.719.8%5.5×92 -32.7%
2Rockefeller UniversityUnited States 67.020.6%41.5×14 +38.1%
3University of California, San FranciscoUnited States 56.016.5%10.2×38 -39.9%
4Johns Hopkins UniversityUnited States 55.411.6%8.8×72 -29.9%
5Cornell UniversityUnited States 50.215.2%5.2×36 -4.8%
6University of California San DiegoUnited States 48.611.4%8.0×41 -35.3%
7University of North Carolina at Chapel HillUnited States 47.44.1%14.5×136 -36.2%
8Emory UniversityUnited States 46.713.0%10.1×43 -29.6%
9Capital Medical UniversityChina 44.810.1%7.1×40 +49.6%
10University of WashingtonUnited States 43.711.0%6.3×38 -18.3%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in HIV Research and Treatment, country by country

Is HIV Research and Treatment research growing?

Output in 2022-2025 was 20% lower than in 2018-2021, peaking in 2014.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is HIV Research and Treatment as a percentage of every work published that year, 0.023% in 2024.

still counting0.050%0.10%0.15%HIV Research and Treatment0.024% in 202519801990200020102020

Fractional works of HIV Research and Treatment over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%HIV Research and Treatment9.8% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

Questions people ask

Who is researching a cure for HIV?

By volume in 2022-now, University of North Carolina at Chapel Hill publishes the most HIV Research and Treatment research, followed by National Institutes of Health and Harvard University. By volume, the United States and China publish the most (2.1k and 775 works in 2022-now).

How much research is there on HIV, and is it growing?

Output in 2022-2025 was 20% lower than in 2018-2021, peaking in 2014.

Is HIV Research and Treatment research growing?
All 1,273 questions in the Question Catalogue

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