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Topic · Cardiology and Cardiovascular Medicine

Takotsubo Cardiomyopathy and Associated Phenomena

Takotsubo Cardiomyopathy and Associated Phenomena is a research topic within Cardiology and Cardiovascular Medicine. Science Explorer counts 11k research works in it since 1950. 10.3% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the pathophysiology, clinical features, and outcomes of stress-induced cardiomyopathy, also known as Takotsubo Syndrome. It delves into the role of neurohumoral features, catecholamine cardiotoxicity, and the brain-heart axis in the development of this condition. Additionally, it investigates the association with neurogenic pulmonary edema, cardiac troponin elevation, myocardial stunning, and its occurrence after subarachnoid hemorrhage.

  • Stress-Induced Cardiomyopathy
  • Takotsubo Syndrome
  • Neurohumoral Features
  • Apical Ballooning Syndrome
  • Catecholamine Cardiotoxicity
  • Neurogenic Pulmonary Edema
  • Cardiac Troponin Elevation
  • Brain-Heart Axis
  • Myocardial Stunning
  • Subarachnoid Hemorrhage
Research works
11k
fractional, since 1950
In the world top 10%
1.2k
per year above
Top-10% rate
10.3%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+18%
the tick is no change
Largest producer
United States
44% of the 10 largest, 2022-now
Takotsubo Cardiomyopathy and Associated Phenomena

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Takotsubo Cardiomyopathy and Associated Phenomena research?

By volume, the United States and China publish the most (879 and 270 works in 2022-now).

By volume, 2022-now

  1. 1 United States 879 works
  2. 2 China 270 works
  3. 3 Japan 183 works
  4. 4 Italy 147 works
  5. 5 India 122 works
  6. 6 United Kingdom 110 works
  7. 7 Germany 92 works
  8. 8 Spain 80 works
  9. 9 France 60 works
  10. 10 Türkiye 59 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 43.9%China: 13.5%Japan: 9.2%Italy: 7.3%6 others listed: 26.1%44%largest
United States879 · 43.9%China270 · 13.5%Japan183 · 9.2%Italy147 · 7.3%6 others listed523 · 26.1%

Shares of the rows listed above, not of the whole node.

Which institutions lead Takotsubo Cardiomyopathy and Associated Phenomena research?

By volume in 2022-now, Mayo Clinic publishes the most Takotsubo Cardiomyopathy and Associated Phenomena research, followed by Harvard University and Cleveland Clinic.

By volume, 2022-now

  1. 1 Mayo ClinicUnited States 34 works
  2. 2 Harvard UniversityUnited States 23 works
  3. 3 Cleveland ClinicUnited States 17 works
  4. 4 New York Medical CollegeUnited States 15 works
  5. 5 All India Institute of Medical SciencesIndia 14 works
  6. 6 Mount Sinai Health SystemUnited States 13 works
  7. 7 Capital Medical UniversityChina 12 works
  8. 8 Northwell HealthUnited States 11 works
  9. 9 Albert Einstein College of MedicineUnited States 11 works
  10. 10 University of GothenburgSweden 11 works

Who are the leading researchers in Takotsubo Cardiomyopathy and Associated Phenomena?

The most-cited researchers publishing on Takotsubo Cardiomyopathy and Associated Phenomena include John J.V. McMurray, Emelia J. Benjamin and Valery L. Feigin.

  1. 1 John J.V. McMurray United Kingdom 349k citations
  2. 2 Emelia J. Benjamin United States 341k citations
  3. 3 Valery L. Feigin New Zealand 341k citations
  4. 4 Stephan Windecker Switzerland 338k citations
  5. 5 Mika Kivimäki United Kingdom 318k citations
  6. 6 Graeme J. Hankey Australia 316k citations
  7. 7 Gregory Y.H. Lip United Kingdom 311k citations
  8. 8 Salim Yusuf Canada 294k citations
  9. 9 Josef Coresh United States 272k citations
  10. 10 Victoria Delgado Netherlands 269k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Takotsubo Cardiomyopathy and Associated Phenomena?

The most cited paper in Takotsubo Cardiomyopathy and Associated Phenomena is "Fourth Universal Definition of Myocardial Infarction (2018)" (Kristian A. Thygesen, Joseph S. Alpert, Allan S. Jaffe et al., 2018), with 3,843 citations. Next come "Guidelines for the Management of Aneurysmal Subarachnoid Hemorrhage" (3,551) and "Neurohumoral Features of Myocardial Stunning Due to Sudden Emotional Stress" (3,132).

Most cited papers
#PaperReleasedCitations
1 Fourth Universal Definition of Myocardial Infarction (2018) Kristian A. Thygesen, Joseph S. Alpert, Allan S. Jaffe et al. · Circulation Open access 16 Oct 2018 3,843
2 Guidelines for the Management of Aneurysmal Subarachnoid Hemorrhage Edward Sander Connolly, Alejandro A. Rabinstein, Juan Ricardo Carhuapoma et al. · Stroke Open access 4 May 2012 3,551
3 Neurohumoral Features of Myocardial Stunning Due to Sudden Emotional Stress Ilan Shor Wittstein, David R. Thiemann, João A.C. Lima et al. · New England Journal of Medicine Open access 9 Feb 2005 3,132
4 Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy Christian Templin et al. · New England Journal of Medicine Open access 2 Sep 2015 2,598
5 Depression Following Myocardial Infarction Nancy Frasure‐Smith · JAMA 20 Oct 1993 1,951
All 99 most cited papers, with filters and sorting

Where is Takotsubo Cardiomyopathy and Associated Phenomena research done?

The largest centres of Takotsubo Cardiomyopathy and Associated Phenomena research in 2022-now are New York (United States), Beijing (China), Tokyo (Japan) and London (United Kingdom). Among places with at least 20 works in it, it is an unusually large share of all research in Cleveland.

Largest cities, 2022-now

  1. 1 New YorkUnited States 48 works
  2. 2 BeijingChina 46 works
  3. 3 TokyoJapan 39 works
  4. 4 LondonUnited Kingdom 32 works
  5. 5 RomeItaly 30 works
  6. 6 MadridSpain 27 works
  7. 7 BostonUnited States 27 works
  8. 8 ClevelandUnited States 27 works
  9. 9 AthensGreece 22 works
  10. 10 ChicagoUnited States 20 works

Where it is the local speciality

  1. ClevelandUS · 27.2 works7.0×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Takotsubo Cardiomyopathy and Associated Phenomena than the world average.

See Takotsubo Cardiomyopathy and Associated Phenomena on the map

Where is the best place to study Takotsubo Cardiomyopathy and Associated Phenomena?

Among universities, judged by research, Harvard University, University of Gothenburg and Università Cattolica del Sacro Cuore score highest, combining citation excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%mean 12.83%fractional works in this field (log) →share of work in the world top 10% →Università Cattolica…University of ZurichUniversity of Gothen…Harvard University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Citation excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Harvard UniversityUnited States 69.311.2%3.0×23 -18.1%
2University of GothenburgSweden 68.416.8%9.6×11 +45.9%
3Università Cattolica del Sacro CuoreItaly 65.021.3%8.1×8 +57.3%
4University of ZurichSwitzerland 57.317.0%5.1×9 +2.2%
5Capital Medical UniversityChina 55.315.8%4.7×12 +116.1%
6New York Medical CollegeUnited States 47.06.7%26.4×14 +93.7%
7Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 45.812.9%4.2×11 +73.4%
8Albert Einstein College of MedicineUnited States 42.85.9%13.5×11 +41.1%
9National and Kapodistrian University of AthensGreece 40.510.8%7.1×9 +348.1%
10Yale UniversityUnited States 37.59.9%3.3×9 +17.9%

Universities only. The score blends citation excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Takotsubo Cardiomyopathy and Associated Phenomena, country by country

Is Takotsubo Cardiomyopathy and Associated Phenomena research growing?

Output in 2022-2025 was 18% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Takotsubo Cardiomyopathy and Associated Phenomena.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Takotsubo Cardiomyopathy and Associated Phenomena as a percentage of every work published that year, 0.010% in 2024.

still counting0.0050%0.010%0.015%Takotsubo Cardiomyopathy and Associated Phenomena0.012% in 202519801990200020102020

Fractional works of Takotsubo Cardiomyopathy and Associated Phenomena over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Takotsubo Cardiomyopathy and Associated Phenomena10.4% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

Discussion

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