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Company · Palo Alto · United States

System Biosciences (United States)

systembio.comROR OpenAlex
World rank, all time
#33,202
of 34,923
Rank in United States
#6,964
of 7,310
Research works
132
▲ 130% vs 2018-21
Citations
8.8k
66.8 per fractional work
Top-10% rate
14.4%
all institutions 10.0%
vs its own fields
1.10×
1.00× is exactly expected
Open access
44%
world 40%
International
14%
world 18%
System Biosciences (United States)

Which fields of science does System Biosciences (United States) work in?

In 2022-now, 46% of research at System Biosciences (United States) is in Health Sciences, 30% in Life Sciences. Its largest fields are Medicine (46%), Biochemistry, Genetics and Molecular Biology (25%), Computer Science (12%). It does 1.6× the world's share of Health Sciences.

Health Sciences: 10 fractional works · 46.2% of its workMedicine: 10 fractional works · 45.6% of its workOncology: 4 fractional works · 15.9% of its workRadiology, Nuclear Medicine and Imaging: 1 fractional works · 5.8% of its workCardiology and Cardiovascular Medicine: 1 fractional works · 4.5% of its workPulmonary and Respiratory Medicine: 1 fractional works · 4.0% of its workSurgery: 1 fractional works · 3.7% of its workRheumatology: 0 fractional works · 1.6% of its workPsychiatry and Mental health: 0 fractional works · 1.5% of its workUrology: 0 fractional works · 1.5% of its workPublic Health, Environmental and Occupational Health: 0 fractional works · 1.4% of its workPhysiology: 0 fractional works · 1.3% of its workHematology: 0 fractional works · 1.1% of its workEpidemiology: 0 fractional works · 0.9% of its workHealth Informatics: 0 fractional works · 0.6% of its workNephrology: 0 fractional works · 0.5% of its workPathology and Forensic Medicine: 0 fractional works · 0.5% of its workGenetics: 0 fractional works · 0.3% of its workNeurology: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.3% of its workHealth Professions: 0 fractional works · 0.4% of its workHealth Information Management: 0 fractional works · 0.4% of its workSmaller subfields together: 0 fractional works · 0.0% of its workVeterinary: 0 fractional works · 0.3% of its workSmall Animals: 0 fractional works · 0.3% of its workLife Sciences: 7 fractional works · 29.7% of its workBiochemistry, Genetics and Molecular Biology: 6 fractional works · 24.7% of its workMolecular Biology: 4 fractional works · 18.8% of its workBiophysics: 0 fractional works · 2.0% of its workBiotechnology: 0 fractional works · 1.2% of its workCancer Research: 0 fractional works · 1.2% of its workCell Biology: 0 fractional works · 0.7% of its workBiochemistry: 0 fractional works · 0.5% of its workGenetics: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.2% of its workAgricultural and Biological Sciences: 1 fractional works · 2.5% of its workPlant Science: 0 fractional works · 1.6% of its workFood Science: 0 fractional works · 0.8% of its workSmaller subfields together: 0 fractional works · 0.1% of its workImmunology and Microbiology: 0 fractional works · 2.2% of its workImmunology: 0 fractional works · 2.2% of its workNeuroscience: 0 fractional works · 0.3% of its workPhysical Sciences: 5 fractional works · 23.1% of its workComputer Science: 3 fractional works · 12.3% of its workArtificial Intelligence: 1 fractional works · 4.9% of its workComputer Vision and Pattern Recognition: 1 fractional works · 3.3% of its workComputer Networks and Communications: 0 fractional works · 1.6% of its workInformation Systems: 0 fractional works · 0.9% of its workHardware and Architecture: 0 fractional works · 0.8% of its workSignal Processing: 0 fractional works · 0.8% of its workEngineering: 2 fractional works · 8.2% of its workBiomedical Engineering: 1 fractional works · 3.7% of its workElectrical and Electronic Engineering: 0 fractional works · 1.7% of its workAutomotive Engineering: 0 fractional works · 0.8% of its workComputational Mechanics: 0 fractional works · 0.8% of its workMechanical Engineering: 0 fractional works · 0.8% of its workAerospace Engineering: 0 fractional works · 0.5% of its workMaterials Science: 0 fractional works · 1.9% of its workBiomaterials: 0 fractional works · 0.8% of its workMaterials Chemistry: 0 fractional works · 0.8% of its workCeramics and Composites: 0 fractional works · 0.4% of its workEnvironmental Science: 0 fractional works · 0.8% of its workEcological Modeling: 0 fractional works · 0.8% of its workSocial Sciences: 0 fractional works · 0.9% of its workDecision Sciences: 0 fractional works · 0.9% of its workInformation Systems and Management: 0 fractional works · 0.9% of its workALL ITS WORKSystemBiosciences…22fractional works, 2022-now
Life Sciences30%Physical Sciences23%Health Sciences46%Social Sciences1%

Each ring splits the one inside it: the four domains of science, their fields, their subfields. Size is fractional works in 2022-now. Every slice is a page; the interactive view zooms down to single topics and colours each by how much more of it this institution does than the world.

Its 4 domains and 12 fields, with their numbers
    1. Medicine1045.6%
    2. Health Professions00.4%
    3. Veterinary00.3%
    1. Biochemistry, Genetics and Molecular Biology624.7%
    2. Agricultural and Biological Sciences12.5%
    3. Immunology and Microbiology02.2%
    4. Neuroscience00.3%
    1. Computer Science312.3%
    2. Engineering28.2%
    3. Materials Science01.9%
    4. Environmental Science00.8%
    1. Decision Sciences00.9%
All of science, and how each field's share has moved since 1950: the Science domain explorer

Field profile

Location quotient across every field it publishes in: outside the ring is more than an institution of this size would be expected to publish, inside it is less.

Agricultural and Biological Sciences: 0.53× its world share, 1 worksAgricultural and Bio…Biochemistry, Genetics and Molecular Biology: 4.64× its world share, 6 worksBiochemistry, Geneti…Immunology and Microbiology: 2.20× its world share, 0 worksImmunology and Micro…Neuroscience: 0.18× its world share, 0 worksNeuroscienceComputer Science: 1.58× its world share, 3 worksComputer ScienceEngineering: 0.55× its world share, 2 worksEngineeringEnvironmental Science: 0.15× its world share, 0 worksEnvironmental ScienceMaterials Science: 0.53× its world share, 0 worksMaterials ScienceHealth Professions: 0.16× its world share, 0 worksHealth ProfessionsMedicine: 2.37× its world share, 10 worksMedicineVeterinary: 1.82× its world share, 0 worksVeterinaryDecision Sciences: 0.93× its world share, 0 worksDecision Sciences1×world share
more than its size predictsabout as predictedless

Rings at 0.5×, 1× and 2×. Widest outward: Biochemistry, Genetics and Molecular Biology, 4.6×. Every wedge is a field page.

All 12 fields, with their numbers
  1. Biochemistry, Genetics and Molecular Biology4.64×6 works
  2. Medicine2.37×10 works
  3. Immunology and Microbiology2.20×0 works
  4. Veterinary1.82×0 works
  5. Computer Science1.58×3 works
  6. Decision Sciences0.93×0 works
  7. Engineering0.55×2 works
  8. Agricultural and Biological Sciences0.53×1 works
  9. Materials Science0.53×0 works
  10. Neuroscience0.18×0 works
  11. Health Professions0.16×0 works
  12. Environmental Science0.15×0 works

Who are the top researchers at System Biosciences (United States)?

Ranked on the quality score, Fangting Wu, Travis J. Antes and Nandita Sarkar lead among researchers whose main affiliation is System Biosciences (United States).

  1. 1 Fangting Wu United States · #428,074 worldwide 3.6k citations · 39 works
  2. 2 Travis J. Antes United States · #2,250,442 worldwide 1.6k citations · 59 works
  3. 3 Nandita Sarkar United States · #4,211,054 worldwide 256 citations · 17 works
  4. 4 Amirali Afshari United States · #5,432,329 worldwide 102 citations · 18 works
All ranked researchers at System Biosciences (United States)

What are the most cited papers from System Biosciences (United States)?

The most cited paper from System Biosciences (United States) is "Isolation of a candidate human hematopoietic stem-cell population." (Claire Baum, Irving L. Weissman, Atsushi Tsukamoto et al., 1992), with 1,098 citations. Next come "Allosteric inhibition of lysyl oxidase–like-2 impedes the development of a pathologic microenvironment" (872) and "Optimized Codon Usage and Chromophore Mutations Provide Enhanced Sensitivity with the Green Fluorescent Protein" (454).

Most cited papers
#PaperReleasedCitations
1 Isolation of a candidate human hematopoietic stem-cell population. Claire Baum, Irving L. Weissman, Atsushi Tsukamoto et al. · Proceedings of the National Academy of Sciences Open access Apr 1992 1,098
2 Allosteric inhibition of lysyl oxidase–like-2 impedes the development of a pathologic microenvironment Vivian Barry-Hamilton et al. · Nature Medicine Sep 2010 872
3 Optimized Codon Usage and Chromophore Mutations Provide Enhanced Sensitivity with the Green Fluorescent Protein Ting Yang, Linzhao Cheng, Steven R. Kain · Nucleic Acids Research Open access Nov 1996 454
4 Negative regulation of lncRNA GAS5 by miR-21 Zhiren Zhang, Zhe Zhu, Kounosuke Watabe et al. · Cell Death and Differentiation Open access 9 Aug 2013 423
5 Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX–ENL Catherine Lavau, Stephen J. Szilvassy, Robert Slany et al. · The EMBO Journal Open access 15 Jul 1997 410
All 60 most cited papers, with filters and sorting

Which keywords describe research at System Biosciences (United States)?

By fractional works in 2022-now, weighted toward what it does more of than the world: Breast Cancer, Chemotherapy, Machine Learning, Deep Learning, Immunotherapy, HER2, Trastuzumab and Monoclonal Antibodies.

▲ more of its work than of the world's◆ about the world's share▼ less than the world's

Size is fractional works in 2022-now in the topics tagged with each word; colour is the word's share of this institution's work against its share of the world's. The 11 words are chosen for being large and distinctive. Each links to the topic it comes from most.

All 11 words, with their numbers
  1. Machine Learning2▲ 2.9×9 topics
  2. Deep Learning2▲ 2.8×11 topics
  3. Breast Cancer2▲ 27×2 topics
  4. Chemotherapy2▲ 9.4×2 topics
  5. Immunotherapy1▲ 7.8×7 topics
  6. HER21▲ 164×1 topic
  7. Trastuzumab1▲ 104×1 topic
  8. Quality of Life1▲ 3.3×3 topics
  9. Metastatic Breast Cancer1▲ 76×2 topics
  10. Monoclonal Antibodies1▲ 52×2 topics
  11. Therapeutic Antibodies1▲ 67×2 topics

Which research topics does System Biosciences (United States) publish most on?

By volume in 2022-now: HER2/EGFR in Cancer Research, Monoclonal and Polyclonal Antibodies Research, Cancer Treatment and Pharmacology and CAR-T cell therapy research.

HER2/EGFR in Cancer Rese…1HER2/EGFR in Cancer Research: 1 fractional worksMonoclonal and Polyclonal Antibodies Research: 1 fractional worksCancer Treatment and Pha…1Cancer Treatment and Pharmacology: 1 fractional worksCAR-T cell therapy resea…0CAR-T cell therapy research: 0 fractional worksNanofabrication and Lithography Techniques: 0 fractional worksCardiac electrophysiology and arrhythmias: 0 fractional worksPulmonary Hypertension R…0Pulmonary Hypertension Research and Treatments: 0 fractional worksSingle-cell and spatial transcriptomics: 0 fractional worksCell Image Analysis Techniques: 0 fractional worksAI in cancer detection0AI in cancer detection: 0 fractional works
OncologyRadiology, Nuclear Medicine and ImagingBiomedical EngineeringCardiology and Cardiovascular Medicine4 others

Area is fractional works; colour is the subfield each topic belongs to.

  1. 1 HER2/EGFR in Cancer Research Oncology 1 works
  2. 2 Monoclonal and Polyclonal Antibodies Research Radiology, Nuclear Medicine and Imaging 1 works
  3. 3 Cancer Treatment and Pharmacology Oncology 1 works
  4. 4 CAR-T cell therapy research Oncology 0 works
  5. 5 Nanofabrication and Lithography Techniques Biomedical Engineering 0 works
  6. 6 Cardiac electrophysiology and arrhythmias Cardiology and Cardiovascular Medicine 0 works
  7. 7 Pulmonary Hypertension Research and Treatments Pulmonary and Respiratory Medicine 0 works
  8. 8 Single-cell and spatial transcriptomics Molecular Biology 0 works
  9. 9 Cell Image Analysis Techniques Biophysics 0 works
  10. 10 AI in cancer detection Artificial Intelligence 0 works

How open and international is its research?

Against the world's own shares: the tick on each track. Both are shares of its output, so they sit on one scale and can be read against each other as well as against the world.

openly available44.2%not open55.8%

World: 40% of research is openly available.

with international co-authors14.3%domestic only85.7%

World: 18% is written across borders.

How has System Biosciences (United States)'s research output changed?

Output in 2022-2025 was 130% higher than in 2018-2021.

still counting1990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is System Biosciences (United States) as a percentage of every work published that year, 0.000019% in 2024.

still counting0.0010%0.0020%System Biosciences (United States)0.00012% in 20251990200020102020

Fractional works of System Biosciences (United States) over all fractional works that year. How the balance of science has shifted.

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