Amyotrophic Lateral Sclerosis Research
Amyotrophic Lateral Sclerosis Research is a research topic within Neurology. Science Explorer counts 21k research works in it since 1950. 25.4% of them reached the world's top 10% most cited for their field and year.
This cluster of papers focuses on the molecular mechanisms, genetics, and pathology of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD). It covers topics such as TDP-43, FUS/TLS, C9ORF72 mutations, neurodegeneration of motor neurons, RNA processing, progranulin deficiency, ubiquitin-positive inclusions, and the genetic underpinnings of these diseases.
- TDP-43
- FUS/TLS
- C9ORF72
- mutations
- neurodegeneration
- motor neurons
- RNA processing
- progranulin
- ubiquitin-positive inclusions
- genetics
- Research works
- 21k fractional, since 1950
- In the world top 10%
- 5.2k per year above
- Top-10% rate
- 25.4% share of its works in the world top 10%
- Growth, 2013–17 → 2018–22
- +26% the tick is no change
This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.
Which countries lead Amyotrophic Lateral Sclerosis Research research?
By volume, the United States and China publish the most (1.1k and 538 works in 2022–2025).
By volume, 2022–2025
- 1 United States 1.1k works
- 2 China 538 works
- 3 Italy 361 works
- 4 United Kingdom 344 works
- 5 Japan 244 works
- 6 Germany 225 works
- 7 Canada 168 works
- 8 Australia 161 works
- 9 Spain 150 works
- 10 France 146 works
How concentrated that is
The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.
Shares of the rows listed above, not of the whole node.
Which institutions lead Amyotrophic Lateral Sclerosis Research research?
By volume in 2022–2025, University College London publishes the most Amyotrophic Lateral Sclerosis Research research, followed by University of Sheffield and University of Pennsylvania.
By volume, 2022–2025
- 1 University College LondonUnited Kingdom 29 works
- 2 University of SheffieldUnited Kingdom 24 works
- 3 University of PennsylvaniaUnited States 23 works
- 4 German Center for Neurodegenerative DiseasesGermany 21 works
- 5 University of California, San FranciscoUnited States 20 works
- 6 Massachusetts General HospitalUnited States 20 works
- 7 Harvard UniversityUnited States 20 works
- 8 Johns Hopkins UniversityUnited States 18 works
- 9 The University of SydneyAustralia 17 works
- 10 InsermFrance 17 works
Who are the leading researchers in Amyotrophic Lateral Sclerosis Research?
The most-cited researchers publishing on Amyotrophic Lateral Sclerosis Research include Ettore Beghi, John Hardy and Ronald C. Petersen.
- 1 Ettore Beghi Italy 4.6k citations
- 2 John Hardy United Kingdom 4k citations
- 3 Ronald C. Petersen United States 4k citations
- 4 Kaj Blennow Sweden 3.4k citations
- 5 David S. Knopman United States 3.2k citations
- 6 Clifford R. Jack United States 3.1k citations
- 7 Henrik Zetterberg Sweden 3.1k citations
- 8 David A. Bennett United States 3k citations
Ranked by citations received across their whole record, among researchers with at least three works on this topic.
Where is Amyotrophic Lateral Sclerosis Research research done?
The largest centres of Amyotrophic Lateral Sclerosis Research research in 2022–2025 are London (United Kingdom), Beijing (China), Tokyo (Japan) and Paris (France). Among places with at least 20 works in it, it is an unusually large share of all research in Sheffield and Bonn.
Largest cities, 2022–2025
Where it is the local speciality
- SheffieldGB · 29.8 works9.3×
- BonnDE · 25.9 works7.7×
Location quotient: how much more of its research is in Amyotrophic Lateral Sclerosis Research than the world average.
Where is the best place to study Amyotrophic Lateral Sclerosis Research?
Among universities, judged by research, University of Sheffield, University College London and University of Massachusetts Chan Medical School score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.
One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.
| # | University | Score | Top 10% | Specialisation | Works | Growth |
|---|---|---|---|---|---|---|
| 1 | University of SheffieldUnited Kingdom | 71.3 | 29.2% | 10.6× | 24 | +27.9% |
| 2 | University College LondonUnited Kingdom | 65.2 | 34.6% | 4.7× | 29 | +27.6% |
| 3 | University of Massachusetts Chan Medical SchoolUnited States | 64.0 | 44.9% | 13.4× | 9 | +43.0% |
| 4 | Trinity College DublinIreland | 63.9 | 29.9% | 8.4× | 12 | +119.8% |
| 5 | Karolinska InstitutetSweden | 63.5 | 31.3% | 6.6× | 13 | +111.9% |
| 6 | Universität UlmGermany | 62.1 | 27.6% | 20.3× | 14 | +50.9% |
| 7 | Macquarie UniversityAustralia | 59.2 | 30.8% | 6.2× | 10 | +714.3% |
| 8 | Harvard UniversityUnited States | 56.3 | 33.5% | 3.6× | 20 | +68.1% |
| 9 | The University of SydneyAustralia | 55.1 | 31.5% | 4.0× | 17 | +95.7% |
| 10 | University of California, San FranciscoUnited States | 54.9 | 22.5% | 7.1× | 20 | +45.8% |
Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.
Is Amyotrophic Lateral Sclerosis Research research growing?
Output in 2018–2022 was 26% higher than in 2013–2017, peaking in 2025. The fastest-growing topics are Amyotrophic Lateral Sclerosis Research.
The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.
Which topics inside it are moving
Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.